People
Ana Maria Valentim
Laboratory Animal Science
Post-Doc Researcher
Researcher with a degree in Biology and a PhD in Veterinarian Sciences. After one year of post-doctoral research in the effects of anaesthesia in rodents, a two year FCT project as a Principal Investigator was funded regarding the effects of anaesthesia in zebrafish using behavioural tasks, morphology, genetics, cellular alterations and oxidative stress evaluation (IBMC, UTAD, CNBC). Currently, an individual post-doctoral fellowship is underway with the aim of optimizing zebrafish anaesthesia using a clinical and animal welfare perspective. Besides the line of research of laboratory animals anaesthesia refinement, the finding of better euthanasia methods and other issues in laboratory animal science are also topics of interest. Trainer in the Laboratory Animal Science course FELASA (cat C) at IBMC.

Selected Publications
Morphological and behavioral responses of zebrafish after 24 h of ketamine embryonic exposure. Toxicology and Applied Pharmacology321:27-36, 2017. [Journal: Article] [CI: 3] [IF: 3,8 (*)]
DOI: 10.1016/j.taap.2017.02.013 SCOPUS: 85013752088

Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology234(4):549-558, 2017. [Journal: Article] [CI: 3] [IF: 3,3 (*)]
DOI: 10.1007/s00213-016-4491-7 SCOPUS: 85001555685

Report of workshop on euthanasia for zebrafish - a matter of welfare and science. Zebrafish14(6):547-551, 2017. [Journal: Article] [CI: 1] [IF: 2,2 (*)]
DOI: 10.1089/zeb.2017.1508 SCOPUS: 85036516157

A new anaesthetic protocol for adult zebrafish (Danio rerio): Propofol combined with lidocaine. PLoS ONE11(1):, 2016. [Journal: Article] [CI: 3] [IF: 2,8]
DOI: 10.1371/journal.pone.0147747 SCOPUS: 84959205162

Euthanizing zebrafish legally in Europe: Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?. EMBO Reports17(12):1688-1689, 2016. [Journal: Note] [IF: 8,6]
DOI: 10.15252/embr.201643153 SCOPUS: 84995451033

Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement. Laboratory Animals50(6):476-488, 2016. [Journal: Article] [CI: 1] [IF: 1,5]
DOI: 10.1177/0023677216670686 SCOPUS: 85014491998

Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task. Applied Animal Behaviour Science189:91-97, 2017. [Journal: Article] [IF: 1,8 (*)]
DOI: 10.1016/j.applanim.2017.01.012 SCOPUS: 85011556791

The memory stages of a spatial Y-maze task are not affected by a low dose of ketamine/midazolam. European Journal of Pharmacology712(1-3):39-47, 2013. [Journal: Article] [CI: 3] [IF: 2,7]
DOI: 10.1016/j.ejphar.2013.04.027 SCOPUS: 84878219774

Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations. Anesthesiology113(5):1099-1108, 2010. [Journal: Article] [CI: 35] [IF: 5,5]
DOI: 10.1097/ALN.0b013e3181f79c7c SCOPUS: 78049352411