VIII National RNA Meeting: ptRNA2019

24 - 25 January 2019 | i3S, Porto

 

 

Welcome

The VIII Portuguese Meeting: ptRNA2019 will bring together at the i3S, Porto, national and international scientists interested on RNA. The meeting aims to promote scientific discussions and synergies in the most recent advances and cutting-edge technologies in RNA, gathering established and young scientists from the country, and also leading international guest speakers. The meeting will feature talks from invited speakers and from young scientists, as well as talks selected from submitted abstracts, a poster session, award to the best poster, and also activities to promote discussion and interaction between the participants. The topics will include RNA and chromatin dynamics, RNA processing, RNA modifications, RNA stability and decay, non-coding RNAs, tRNAs biology, RNA function in gene expression regulation in health and disease.

Looking forward to welcoming you to the beautiful city of Porto!

 

 

Organization

Organizing Committee

Alexandra Moreira, i3S/IBMC, ICBAS, Porto
Margarida Gama-Carvalho, BIoISI-FCUL, Lisboa
Isabel Pereira-Castro, i3S/IBMC, Porto
Jaime Freitas, i3S/IBMC, Porto

 

 

Scientific Committee

Carmo-Fonseca, IMM, Lisboa
Manuel Santos, iBiMED, Aveiro
Cecília Arraiano, UNL, Lisboa
Leonor Cancela, Universidade do Algarve, Faro
Carla Oliveira, i3S/IPATIMUP, Porto
Peter Jordan, INSA, Lisboa
Isabel Sá Nogueira, UCIBIO/FCT-NOVA, Lisboa
Margarida Gama-Carvalho, BIoISI-FCUL, Lisboa
Raquel Chaves, UTAD, Vila Real
Luísa Romão, INSA, Lisboa
Francisco Enguita, IMM, Lisboa
Alekos Athanasiadis, IGC, Oeiras
Alexandra Moreira, i3S/IBMC, ICBAS, Porto

 

Program

Thursday | 24 January 2019

 

15:00-15:15 Registration

 

15:30-15:45 WELCOME ADDRESS

Alexandra Moreira, i3S / IBMC, ICBAS, Porto

 

15:45-16:30 KEYNOTE LECTURE

A novel class of regulatory antisense non-coding RNAs

Carmo Fonseca, IMM, Lisboa

 

16:30-17:00 Coffee Break

 

17:00-18:00  SESSION I – RNA in microorganisms

Chair: Leonor Cancela, Universidade do Algarve, Faro

 

Cecília Arraiano, ITQB, UNL, Lisbon

 

RNAs in Bacillus subtilis: Transcription and beyond

Isabel Sá-Nogueira, UCIBIO/FCT-NOVA, Lisbon

 

Systems biology approaches identify host microRNAs controlling infection by bacterial pathogens.

Ana Eulálio, Biocant, Cantanhede

 

18:00-18:30 - ROUND TABLE

History of ptRNA; Introduction of ptRNA as a platform for scientific discussions on RNA Biology in Portugal; Identification of all the Portuguese scientists, including young scientists, with a special interest in RNA Biology.

 

Carmo-Fonseca, IMM, Lisboa

Cecília Arraiano, ITQB, UNL, Lisboa

Leonor Cancela, Universidade do Algarve, Faro

Manuel Santos, iBiMed, Universidade de Aveiro, Aveiro

Margarida Gama-Carvalho, BIoISI-FCUL, Lisboa

Alexandra Moreira, i3S/ IBMC, ICBAS, Porto

 

20:00 Social dinner

 

 


 

Friday | 25 January 2019 

 

KEYNOTE LECTURE

9:00 - 9:30 tRNA modifying enzymes as guardians of proteome homeostasis

Manuel Santos, iBiMed, Univ Aveiro

 

9:30-10:30 SESSION II - RNA in Eukaryotes

Chair: Carmo-Fonseca, IMM, Lisboa

 

Alternative modes of gene expression

Alexandra Moreira, i3S / IBMC, Porto

 

On the significance of alternative splicing in plants: A role for SR proteins in the response to abiotic stress.

Paula Duque, IGC, Oeiras

 

Mechanistic aspects of nonsense-mediated mRNA decay in human cells

Luísa Romão, INSA, Lisbon

 

10:30-11:00 Coffee Break

 

11:00-11:40 SPECIAL SESSION

Four selected talks of Ph.D. students and junior post-docs

 

12:00-13:00  KEYNOTE LECTURE / i3S FRIDAY NOON SEMINAR 

Regulation of 3’UTR-mediated protein-protein interactions.

Christine Mayr, Memorial Sloan Kettering Cancer Center, New York, USA

 

13:00-13:45 Lunch

 

13:45-14:45 POSTER SESSION

 

14:45-15:45 SESSION III - RNA in disease and bioinformatics

Chair: Peter Jordan, INSA, Lisboa

 

CELF2 at the core of a prognostic alternative splicing signature in colorectal cancer.

Nuno Morais, IMM, Lisbon

 

Common RNA-dependent pathways for motor-neuron degeneration in spinocerebellar muscular atrophy and amyotrophic lateral sclerosis.

Margarida Gama Carvalho, BIoISI-FCUL, Lisbon

 

Regulation of the CDH1 locus: intronic sequences command CDH1 expression

Carla Oliveira, i3S, Porto

 

15:45-16:15 SESSION IV - Young PIs in ptRNA 

Chair: Cecília Arraiano, ITQB, UNL, Lisboa

 

LncRNAs in breast cancer.

Bruno Jesus, iBiMED, Aveiro

 

Conflicts between RNA and DNA at human telomeres.

Claus Azzalin, IMM, Lisbon

 

16:15-16:45 Coffee break

 

16:45-17:30 SESSION IV - Young PIs in ptRNA 

Chair: Cecília Arraiano, ITQB, UNL, Lisboa

 

tRNA modifying enzymes: novel proteostasis players in human cells.

Ana Soares, iBiMED, Aveiro

 

Genome-wide analysis of the nascent RNApolII transcriptome during Drosophila development

Rui Martinho, iBiMED, Aveiro and IMM, Lisboa

 

Single-molecule imaging of transcription at damaged chromatin.

Sérgio de Almeida, IMM, Lisbon

 

17:30-18:15 KEYNOTE LECTURE

Restricting the extent of transcription across the mammalian genome to prevent the formation of pathological RNA.

Nick Proudfoot, University of Oxford, Oxford, UK

 

18:15-18:30 Awards to the best poster and Closing remarks

18:30 Porto d’ honra

 

Speakers

Alexandra Moreira

Alexandra Moreira

i3S/IBMC, Porto, Portugal

 

Alexandra Moreira obtained her D.Phil in Molecular Biology from Wolfson College at the University of Oxford in 1997. Her doctorate studies were conducted under Nick Proudfoot supervision at the Sir William Dunn School of Pathology, University of Oxford where she investigated the mRNA 3’ end formation mechanism of the human C2 complement. She then moved back to Porto to work as a postdoctoral fellow with Claudio Sunkel at the IBMC, and in 2003 formed the Group of Cell Activation and Gene Expression. Alexandra Moreira founded the Portuguese RNA Biology work group in 2004. She is currently a Professor in Molecular Biology and holds a Principal Investigator position at ICBAS, University of Porto. Together with her research activities, Alexandra Moreira is a member of the Scientific Board of the Molecular and Cell Biology PhD Program, University Porto, and organizes several yearly courses for PhD Programs. Since 2012 Alexandra Moreira is the Leader of the Group Gene Regulation at IBMC-i3S. The objective of her research group is to understand the molecular mechanisms involved in the integration between RNAPII transcription and alternative pre-mRNA processing, with a focus on polyadenylation, and on those events that are physiologically relevant in Eukaryotes.

 

 


 

Ana Eulálio

Ana Eulálio

Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal

 

Ana Eulálio obtained her PhD in Biochemistry from the University of Coimbra, Portugal, in 2006. She then worked as a postdoctoral fellow at the Max-Planck Institute for Development Biology at Tübingen, Germany, Max-Planck Institute for Infection Biology in Berlin, Germany and at the International Centre for Genetic Engineering and Biotechnology, Trieste, Italy, focusing on various aspects of microRNA mechanisms and function. She was a Group Leader at the Institute for Molecular Infection Biology (IMIB) of the University of Würzburg in Germany. Presently she is a Group Leader at the Center for Neuroscience and Cell Biology (CNC), University of Coimbra. The main goal of Ana Eulálio’s research is to identify host ncRNAs - specifically, microRNAs and long ncRNAs - that regulate and/or are regulated during infection by human bacterial pathogens and to characterize the impact of bacteria on cellular mRNA processing, stability and surveillance pathways of the host.

 

 


 

Ana Raquel Soares

Ana Raquel Soares

Institute of Biomedicine – iBiMED, University of Aveiro, Portugal

 

Ana Raquel Soares is an associate researcher at the Institute of Biomedicine – University of Aveiro, specialized in RNA biology, RNA interference, post-transcriptional regulation and protein quality control. She did her PhD between CNC-UC, University of Aveiro and GiGA research center at Liège, where she studied the impact of microRNAs in vertebrate development and identified a novel class of small non-coding RNAs derived from tRNAs. During her post-doc, she turned to tRNA biology and was involved in the development of an animal model (zebrafish) of translation errors. Currently, Ana Soares is the PI of two funded FCT projects that aim at identifying novel proteostasis-related genes through high content screenings and testing their potential as therapeutic targets, and also in the characterization of protein aggregation through aging at the cellular and organismal level and its relevance for disease onset.

 

 


 

Bruno Bernardes de Jesus

Bruno Bernardes de Jesus

Institute of Biomedicine – iBiMED, University of Aveiro, Portugal

 

Bruno Bernardes de Jesus is currently an Assistant Professor at the Institute of Biomedicine – iBiMED, University of Aveiro, Portugal. Bruno obtained his PhD in Molecular and Cellular Biology at the University Louis Pasteur in Strasbourg, France in 2008. Bruno studied the impact of cancer and aging of mutations in the DNA repair factor XPC at the Functional Genomic Department – J-M Egly, IGBMC. From 2009 to 2013 Bruno was a postdoctoral fellow at CNIO, Madrid, in the group of Maria Blasco, where he investigated the potential applications of telomerase therapies in tissue healing and lifespan extension. From 2014 to 2018 Bruno was an iFCT at iMM, associated with the group of Maria Carmo-Fonseca. There he described the participation of long non-coding RNAs (lncRNAs) during stemness and aging. Bruno Bernardes de Jesus has been mainly focused on understanding molecular aspects of disease progression and aging, using several experimental models spanning from in vitro biochemical studies and cell culture models. His principal research interests are aging, stem cell biology, telomerase, cancer, lncRNAs.

 

 


 

Carla Oliveira

Carla Oliveira

i3S/ Ipatimup, Porto, Portugal

 

Carla Oliveira obtained her PhD in Human Biology/GABBA/ Faculty of Medicine, University of Porto (IPATIMUP & Univ. Cambridge). She did her postdoctoral studies in IPATIMUP, Porto, INSERM, Paris, and the University of British Columbia, Vancouver. She was an Invited researcher at Max Planck Institute, Tübingen. Currently she is an Affiliated Professor in Faculty of Medicine, University of Porto and Group Leader of the Expression Regulation in Cancer Group at i3S/IPATIMUP since 2013. Carla Oliveira is recognized internationally for her work in E-cadherin/CDH1-related diseases. She disclosed molecular and clinical aspects of worldwide series of families and sporadic gastric cancer cases, found novel germline causative defects and defined somatic events in tumours with impact for patient management and therapy. She pioneered the identification of an association between the presence of germline CDH1 mutations and developmental malformations. Carla Oliveira scientific aim is to disclose the missing heritability in Hereditary Gastric Cancer. For this, her team is exploring the noncoding genome. She also aims at finding biomarkers with clinical utility for earlier detection of sporadic and hereditary gastric cancer and to define better treatment regimens. She is the National Representative of the European Reference Network ERN-GENTURIS.

 

 


 

Cecília Arraiano

Cecília Arraiano

Instituto de Tecnologia Química e Biológica, Oeiras, Portugal

 

Cecilia Arraiano obtained her PhD in Genetics from the University of Georgia, USA. She is currently a Research Coordinator at the Instituto de Tecnologia Química e Biológica of the Universidade NOVA de Lisboa, where she heads the Control of Gene Expression Group. She is a member of EMBO and the European Academy of Microbiology, and the Former President of the Portuguese Genetics Society. The main research aim of Cecília Arraiano has been to elucidate factors determinant for the control of gene expression, focusing in the study of RNA degradation mechanisms and the characterization of enzymes that mediate RNA decay in microorganisms. Cecília Arraiano have studied the RNase II family ribonucleases in the maturation, degradation, and quality control of mRNAs and functional non-coding small RNAs. Her studies have been applied to areas of Biotechnological interest and Health and she has been involved in European Projects on Synthetic Biology. Her present work involves not only the understanding of the mechanism of action of RNases and their RNA targets, but also studies on microbial virulence and survival, and the use of synthetic biology to reprogramme bacteria for biotechnology use.

 

 


 

Christine Mayr

Christine Mayr

Memorial Sloan Kettering Cancer Center, New York, USA

 

Christine Mayr is a Member of the Cancer Biology and Genetics Program at Memorial Sloan Kettering Cancer Center and Assistant Professor at Weill Cornell Medical College. Christine Mayr obtained her MD from the Free University, Berlin and her PhD in Immunology in 2001 from the Humboldt University, Berlin, Germany. She moved to the USA in 2005 to work as a postdoctoral fellow with David Bartel at the Whitehead Institute, MIT, Cambridge, MA. There she performed seminal work showing that in cancer cells there is a widespread 3’UTR shortening by alternative cleavage and polyadenylation. Since 2009 she is a Group Leader at the Sloan-Kettering Institute where she is making outstanding contributions to the field. In particular, she has shown that the expression of alternative 3’UTR isoforms is a cell type-specific mechanism, and also that 3’UTRs can regulate protein localization and protein function. Christine Mayr has been awarded with several prizes and honors, including the Merit Award of the American Society of Clinical Oncology, the Kimmel Scholar Award, the Science Signaling Breakthrough of 2013, the Damon Runyon-Rachleff Innovation Award, the NIH Director’s Pioneer Award and the Pershing Square Sohn Prize for Young Investigators in Cancer Research.

 

 


 

Claus Azzalin

Claus Azzalin

Instituto de Medicina Molecular – iMM, Lisboa, Portugal

 

Claus Azzalin did his PhD in Genetics and Molecular Biology (2000), Università degli Studi di Pavia (Italy). He did his Postdoctoral studies at Memorial Sloan-Kettering Cancer (USA, 2001-2002) and in the Swiss Institute for Experimental Cancer Research (Switzerland, 2002-2008) where he discovered that the telomere regions produce RNA with a repetitive sequence that was named TERRA (TElomeric Repeat-containing RNA). He was a group leader in the Eidgenössische Technische Hochschule Zürich (Switzerland) before joining the iMM in 2016. His group employs molecular biology, cell biology and biochemistry to understand how telomeres execute their protective functions and how telomeric dysfunctions are mechanistically linked to pathological conditions. In particular, his group studies how the telomeric long noncoding RNA TERRA participates in maintaining proper telomere structure and functions in both normal and diseased human cells.

 

 


 

Isabel de Sá-Nogueira

Isabel de Sá-Nogueira

UCIBIO/FCT-Universidade Nova de Lisboa, Portugal

 

Isabel de Sá-Nogueira is an Associate Professor at Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (FCT-NOVA), Principal Investigator at UCIBIO, REQUIMTE (FCT-NOVA) and Leader of the Microbial Genetics Laboratory. She received a PhD in Biology (Molecular Biology) from FCT-NOVA in 1991. Her postdoctoral research was carried out at Emory University, Atlanta USA, in 1992. When Isabel Sá-Nogueira returned to Portugal she started an independent line of research and in 1996 became head of the Microbial Genetics Laboratory at Instituto de Tecnologia Química e Biológica (ITQB-NOVA). In 2009 she moved her research group to FCT-NOVA. In 2015 she was elected President of the Portuguese Society of Genetics. Her main field of research is Molecular Microbiology and Microbial Genetics, in particular the control gene expression of carbohydrate metabolism and transport in bacteria. Her main area of interest is to understand how the transcriptional and translational regulatory networks interact with other cellular components such as the metabolic system.

 

 


 

Luísa Romão

Luísa Romão

Instituto Nacional de Saúde Dr. Ricardo Jorge – INSA, Lisboa, Portugal

 

Luísa Romão is the Head of the mRNA Metabolism Group of the Human Genetics Department, at the Portuguese National Institute of Health Doutor Ricardo Jorge (INSA). In 2010, she joined the Center for Biodiversity, Functional & Integrative Genomics at Faculdade de Ciências of Universidade de Lisboa, where, since 2014, she is also an Invited Professor. In 2015, she was elected President of the Portuguese Society of Human Genetics for the year of 2017. As a Group Leader, Luísa Romão is interested in studying mechanisms of post-transcriptional control of gene expression in human health and disease. Half of the research in her lab is focused on mRNA surveillance mechanisms, namely nonsense-mediated decay (NMD) and the other half is interested in the mechanisms of mRNA translational control in human cells and its importance in diseases such as cancer.

 

 


 

Manuel Santos

Manuel Santos

iBiMED, University of Aveiro, Portugal

 

Manuel Santos graduated in Biology in 1988 in Coimbra, did his postdoctoral studies in the United Kingdom at the University of Kent, in France at the IBMC-Strasbourg and in the USA at HHMI-Salt Lake City. He returned to Portugal in 1999 and set up the Aveiro RNA Biology laboratory in 2000. Since then, he developed a research program on the experimental evolution of genetic code alterations, focusing on the biology of protein synthesis fidelity. He studies yeast and human tRNAs, RNA modifying enzymes and aminoacyl-tRNA synthetases. Other studies focus on the role of codon decoding fidelity on protein aggregation and evolution of the genetic code. Manuel Santos also set up the Aveiro Genomics platform and since 2014 coordinates the GenomePT consortium. Manuel Santos was awarded with a Wellcome Trust Career Development Fellowship in 1995, an EMBO Young Investigator Award in 2001 and his research has been funded by EMBO, HFSP, FCT and the EU FP7.

 

 


 

Margarida Gama-Carvalho

Margarida Gama-Carvalho

Instituto de Biossistemas e Ciências Integrativas – BioISI, Faculdade de Ciências, Universidade de Lisboa, Portugal

 

Margarida Gama-Carvalho has a PhD in Biomedical Sciences, Cell and Molecular Biology at the Faculty of Medicine, University of Lisbon. She worked as a postdoctoral researcher at the Dana Farber Cancer Institute in the USA. Since 2011 she is an Assistant Professor at the Faculty of Sciences, Dept. of Chemistry and Biochemistry, University of Lisbon. Presently, she is the Head of the Gene Expression and Regulation Group in the Institute for Biosystems and Integrative Sciences (BioISI), Faculty of Sciences, University of Lisbon. The main goal of Margarida Gama-Carvalho’s Group is to explore the regulation of eukaryotic gene expression programs at the transcriptional and post-transcriptional levels and their connection to signaling pathways, using a combination of cell and molecular biology studies with transcriptomics and bioinformatic approaches.

 

 


 

Maria Carmo-Fonseca

Maria Carmo-Fonseca

iMM, Lisboa, Portugal

 

Maria Carmo-Fonseca obtained her PhD in Cell Biology in 1988 at the Faculty of Medicine of the University of Lisbon and did her postdoctoral research at EMBL, Heidelberg, Germany. She is a Full Professor at the Faculty of Medicine, University of Lisbon. Since 2002 she serves as Executive Director of the Institute of Molecular Medicine (iMM) in Lisbon and since 2014 she iMM President. She has been awarded several prizes and honors including the Gulbenkian Science Award in 2007 and Prémio Pessoa in 2010. Carmo Fonseca is a member of several scientific organizations including EMBO, the Portuguese Academy of Sciences and the Portuguese Academy of Medicine. Carmo-Fonseca’s laboratory aims to discover molecular pathways and mechanisms implicating RNA in human health and disease. Her laboratory has made outstanding contributions to the field of RNA splicing and transcription dynamics, and its role in the regulation of gene expression, by microscopy state-of-the-art methodologies. Ongoing projects in Carmo-Fonseca’s laboratory make use of a multidisciplinary approach that combines live-cell microscopy, computational modeling, molecular biology, biochemistry, and bioinformatics, to explore new medical applications for RNA.

 

 


 

Nicholas Proudfoot

Nicholas Proudfoot

Sir William Dunn School of Pathology, University of Oxford, UK

 

Nicholas Proudfoot is a renowned molecular biologist who has made outstanding contributions to the field of mRNA processing in eukaryotes. He started his scientific career working on mRNA sequencing in 1973 at LMB Cambridge and discovered the AAUAAA poly(A) signal as a graduate student with George Brownlee. In 1989 he took a postdoc position in the USA with Tom Maniatis at Caltech and Harvard, where he cloned and sequenced various globin genes, discovering globin pseudogenes. Nick Proudfoot started his laboratory at the Sir William Dunn School of Pathology, University of Oxford in 1981, where he is a Professor. He was a Fellow and Tutor in Biochemistry at Brasenose College from 1982-2003. Nick Proudfoot has won several prizes and awards, including a Royal Society/Wolfson Research Merit Award, he is an EMBO member, and a Fellow of the Royal Society (FRS). He has co-organized seven four-yearly spaced workshops at Oxford on “Eukaryotic RNA 3’ ends formation and function”. These have provided a major forum for the field as it has developed over the last 40 years. Most recent studies from his laboratory lead to a genomic perspective of how transcription and RNA processing are coupled mechanisms. Nick Proudfoot’s work has been crucial in advancing our current understanding of mRNA.

 

 


 

Nuno Barbosa-Morais

Nuno Barbosa-Morais

Instituto de Medicina Molecular – iMM, Lisboa, Portugal

 

Nuno Barbosa-Morais did his PhD in Biomedical Sciences in 2007 at the Lisbon Medical School with Maria Carmo-Fonseca, with most of the associated research actually taking place at the University of Cambridge with Samuel Aparicio. His PhD work involved bioinformatics studies on the complexity of splicing and gene expression and his efforts include studies on the evolution of splicing factors and the RNA binding of splicing factors. Nuno Barbosa-Morais was a Research Associate in the Computational Biology Group from the University of Cambridge, led by Simon Tavaré and based at the CRUK Cambridge Research Institute, from 2006 to 2010 and a Senior Postdoctoral Fellow with Ben Blencowe at the University of Toronto from 2010 to 2013, being involved in the analysis of mRNA-seq data for the inference of tissue- and species-specific alternative splicing patterns. Nuno Barbosa-Morais was awarded a Postdoctoral Fellowship from the Canadian Institutes of Health Research and a Marie Curie International Outgoing Fellowship. From 2013 to 2015 he was an Honorary Senior Research Fellow at the Nuffield Department of Obstetrics and Gynaecology of the University of Oxford. He established his research group at the iMM in 2015 as an EMBO Installation and an FCT Investigator Grantee.

 

 


 

Paula Duque

Paula Duque

Instituto Gulbenkian de Ciência – IGC, Oeiras, Portugal

 

Paula Duque obtained her PhD in physiology and biochemistry at the University of Lisbon, having conducted part of her doctoral work at the Hort Research Institute in Auckland, New Zealand. Her postdoctoral studies were conducted at The Rockefeller University in New York, first in Nam-Hai Chua’s laboratory on stress signaling in the plant model Arabidopsis thaliana and then with Magda Konarska on the mechanisms of mRNA splicing human cells. Since 2007, she is a Group Leader at the Instituto Gulbenkian de Ciência (IGC), Oeiras, and her research group uses Arabidopsis as a model system and combines reverse genetics, physiology, and biochemistry to investigate how plants perceive and respond to environmental cues at the molecular level. Her major line of work is addressing the biological relevance of alternative splicing in plant systems and has revealed regulatory circuits that link plant development and environmental responses to this key posttranscriptional regulatory mechanism. Paula Duque has won several awards and is an EMBO member.

 

 


 

Rui Martinho

Rui Martinho

iBiMED, Aveiro and IMM, Lisboa, Portugal

 

Rui Martinho joined the Gulbenkian Ph.D. program in Biomedical Sciences (PGDBM) in 1995, where he did his PhD research with Antony Carr at the MRC-Cell Mutation Unit, Sussex University, UK, on DNA-dependent checkpoints in fission yeast. His postdoctoral research was done in the laboratory of Ruth Lehmann at the Skirball Institute, New York University, USA, where he worked with Drosophila primordial germ cells transcriptional regulation. Currently, Rui Martinho is a Group Leader at the Department of Biomedical Sciences and Medicine in the University of Algarve where he takes advantage of Drosophila melanogaster as a model system to study germ-line development, tissue morphogenesis, and cell division during development. Since tumorigenesis is frequently associated with loss of tissue integrity and misregulation of cell proliferation, his work will give a contribution into a better understanding of molecular and cellular processes associated with the onset and development of cancer.

 

 


 

Sérgio de Almeida

Sérgio de Almeida

Instituto de Medicina Molecular - iMM, Lisboa, Portugal

 

Sérgio de Almeida obtained his PhD in Biomedical Sciences from the University of Porto in 2007 under the supervision of Professor Maria de Sousa. He then joined the Instituto de Medicina Molecular (iMM), Lisboa, as a postdoctoral fellow to study mechanisms of gene expression regulation in the Carmo-Fonseca Laboratory. In 2013 he was awarded an FCT Investigator Grant and started his own group at the iMM, Lisboa, to study epigenetics and tumor biology. In the same year, he joined the Faculdade de Medicina da Universidade de Lisboa as an Assistant Professor. Sérgio de Almeida authors several original research papers, including publications in high-impact journals such as Nature Structural and Molecular Biology, eLife, NAR, Cell Reports, Molecular Cell or Genome Research. His work was cited over 1000 times and received national and international awards, such as the 2005 LabMed Science Award, the 2011 Pfizer Award and the 2015 Sociedade Portuguesa de Genética Humana Award.

 

Abstract Submission

Abstract Submission

Call for abstracts will close on the 17th December 2018 and the participants should use the layout provided here: 

 

The meeting will include one special section with four talks selected from the abstracts. These will give young scientists the opportunity to highlight their work.

A lively poster session will also be included in the meeting and the best poster presentation will be awarded a prize kindly provided by the RNA Society.
 

 

 

 

 

 

Registration

Registration

Registration will close on the 31st December 2018.

Registration fee includes coffee breaks, lunch on the 25th January, and meeting material. Social dinner is not included in the registration fee and it has an extra cost of 25€.

 

Fees:

Students - university degree, MSc and PhD students (40 €)*

Regular registration (60 €)

Payment deadline: 7th January 2019

* Students should enclose a document confirming their status in the registration form.

 

 

 

 

Grants:

Limited financial assistance is provided by the RNA Society in the form of travel grants for young scientists

·    The travel grants will cover the cost of travel (train or bus), accommodation and registration fees.

·    Travel grant are restricted to PhD students and postdocs that conduct basic research.

·    The organizers will select the recipients of the travels grants based on: the submitted abstract and a letter specifying the motivation for applying, the reasons for requiring financial support and the impact the event will have on the applicant's career. The motivation letter should have 1000 characters maximum (with spaces included) and it should be submitted online together with the registration form until December 17th 2018.

·    The awardees will be notified until January 8th, 2019.

 

 

MORE INFORMATION:

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