Where Ideas grow
Ana Maria Valentim
Junior Researcher
Researcher with a degree in Biology and a PhD in Veterinarian Sciences. After one year of post-doctoral research in the effects of anaesthesia in rodents, a two year FCT project as a Principal Investigator was funded regarding the effects of anaesthesia in zebrafish using behavioural tasks, morphology, genetics, cellular alterations and oxidative stress evaluation (IBMC, UTAD, CNBC). After an individual post-doctoral fellowship, she is currently a PI of the three-year project ZEBREFINE funded by FCT with the aim of optimizing zebrafish anaesthesia by improving clinical outcomes, avoiding side-effects, and improving animal welfare. Besides the line of research of laboratory animals anaesthesia refinement, the finding of better euthanasia methods and other issues in laboratory animal science are also topics of interest. Trainer in the Laboratory Animal Science course FELASA (cat C) at IBMC.

Selected Publications

Félix L., Serafim C., Martins M., Valentim A., Antunes L., Matos M., Coimbra A.,
Morphological and behavioral responses of zebrafish after 24αh of ketamine embryonic exposure. Toxicology and Applied Pharmacology321:27-36, 2017. [Journal: Article] [CI: 11] [IF: 3,6]
DOI: 10.1016/j.taap.2017.02.013 SCOPUS: 85013752088. .

Félix L., Antunes L., Coimbra A., Valentim A.,
Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology234(4):549-558, 2017. [Journal: Article] [CI: 10] [IF: 3,2]
DOI: 10.1007/s00213-016-4491-7 SCOPUS: 85001555685. .

Köhler A., Collymore C., Finger-Baier K., Geisler R., Kaufmann L., Pounder K., Schulte-Merker S., Valentim A., Varga Z., Weiss J., Strähle U.,
Report of workshop on euthanasia for zebrafish - a matter of welfare and science. Zebrafish14(6):547-551, 2017. [Journal: Article] [CI: 1] [IF: 1,7]
DOI: 10.1089/zeb.2017.1508 SCOPUS: 85036516157. .

Valentim A., Félix L., Carvalho L., Diniz E., Antunes L.,
A new anaesthetic protocol for adult zebrafish (Danio rerio): Propofol combined with lidocaine. PLoS ONE11(1):, 2016. [Journal: Article] [CI: 12] [IF: 2,8]
DOI: 10.1371/journal.pone.0147747 SCOPUS: 84959205162. .

Valentim A., van Eeden F., Strähle U., Olsson I.,
Euthanizing zebrafish legally in Europe: Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?. EMBO Reports17(12):1688-1689, 2016. [Journal: Note] [CI: 3] [IF: 8,6]
DOI: 10.15252/embr.201643153 SCOPUS: 84995451033. .

Martins T., Valentim A., Pereira N., Antunes L.,
Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement. Laboratory Animals50(6):476-488, 2016. [Journal: Article] [CI: 5] [IF: 1,5]
DOI: 10.1177/0023677216670686 SCOPUS: 85014491998. .

Guedes S., Valentim A., Antunes L.,
Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task. Applied Animal Behaviour Science189:91-97, 2017. [Journal: Article] [CI: 2] [IF: 1,5]
DOI: 10.1016/j.applanim.2017.01.012 SCOPUS: 85011556791. .

Valentim A., Ribeiro P., Olsson I., Antunes L.,
The memory stages of a spatial Y-maze task are not affected by a low dose of ketamine/midazolam. European Journal of Pharmacology712(1-3):39-47, 2013. [Journal: Article] [CI: 5] [IF: 2,7]
DOI: 10.1016/j.ejphar.2013.04.027 SCOPUS: 84878219774. .

Valentim A., Di Giminiani P., Ribeiro P., Rodrigues P., Olsson I., Antunes L.,
Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations. Anesthesiology113(5):1099-1108, 2010. [Journal: Article] [CI: 35] [IF: 5,5]
DOI: 10.1097/ALN.0b013e3181f79c7c SCOPUS: 78049352411. .