People
Ana Xavier de Carvalho
Cytoskeletal Dynamics

Ana Carvalho graduated in Biochemistry from the Faculty of Sciences of the University of Porto. She did her doctoral studies on mitosis with Prof. Bill Earnshaw at the Wellcome Trust Centre for Cell Biology in Edinburgh, UK. Her postdoctoral work focused on the study of cytokinesis and was carried out in Prof. Karen Oegema's group at the Ludwig Institute for Cancer Research in San Diego, USA. In 2012, she moved to the Institute for Molecular and Cell Biology in Porto as a Principal Investigator.

Selected Publications
Carvalho A., Desai A., Oegema K.,
Structural Memory in the Contractile Ring Makes the Duration of Cytokinesis Independent of Cell Size. Cell137(5):926-937, 2009. [Journal: Article] [CI: 114] [IF: 31,2]
DOI: 10.1016/j.cell.2009.03.021 SCOPUS: 65849336045. .

De Carvalho A., Maiato H., Maia A., Ribeiro S., Pontes P., Bickmore W., Earnshaw W., Sambade C.,
Reed-sternberg cells form by abscission failure in the presence of functional aurora B kinase. PLoS ONE10(5):, 2015. [Journal: Article] [CI: 7] [IF: 3,1]
DOI: 10.1371/journal.pone.0124629 SCOPUS: 84929096316. .

Silva A., Osório D., Pereira A., Maiato H., Pinto I., Rubinstein B., Gassmann R., Telley I., Carvalho A.,
Robust gap repair in the contractile ring ensures timely completion of cytokinesis. Journal of Cell Biology215(6):789-799, 2016. [Journal: Article] [CI: 3] [IF: 8]
DOI: 10.1083/jcb.201605080 SCOPUS: 85009223214. .

Thieleke-Matos C., Osório D., Carvalho A., Morais-de-Sá E.,
Emerging Mechanisms and Roles for Asymmetric Cytokinesis. International Review of Cell and Molecular Biology332:297-345, 2017. [Book Series: Chapter] [IF: 3,6]
DOI: 10.1016/bs.ircmb.2017.01.004 SCOPUS: 85014702979. .

Mangal S., Sacher J., Kim T., Osório D., Motegi F., Carvalho A., Oegema K., Zanin E.,
TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis. Journal of Cell Biology217(3):837-848, 2018. [Journal: Article] [CI: 4] [IF: 8,8 (*)]
DOI: 10.1083/jcb.201706021 SCOPUS: 85042867550. .

Davies T., Jordan S., Chand V., Sees J., Laband K., Carvalho A., Shirasu-Hiza M., Kovar D., Dumont J., Canman J.,
High-Resolution Temporal Analysis Reveals a Functional Timeline for the Molecular Regulation of Cytokinesis. Developmental Cell30(2):209-223, 2014. [Journal: Article] [CI: 27] [IF: 9,7]
DOI: 10.1016/j.devcel.2014.05.009 SCOPUS: 84904886021. .

Lewellyn L., Carvalho A., Desai A., Maddox A., Oegema K.,
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. Journal of Cell Biology193(1):155-169, 2011. [Journal: Article] [CI: 39] [IF: 10,3]
DOI: 10.1083/jcb.201008138 SCOPUS: 79955513613. .

Carvalho A., Olson S., Gutierrez E., Zhang K., Noble L., Zanin E., Desai A., Groisman A., Oegema K.,
Acute drug treatment in the early C. elegans embryo. PLoS ONE6(9):, 2011. [Journal: Article] [CI: 45] [IF: 4,1]
DOI: 10.1371/journal.pone.0024656 SCOPUS: 80052849441. .