Where Ideas grow
Aureliana Filipa Sousa
Project Leader

Aureliana Sousa has a PhD in Biomedical Sciences (ICBAS) developed at Instituto de Biologia Celular e Molecular (IBMC) on the area of cell cycle finished in 2012 under the supervision of Prof. Claudio Sunkel.

Her postdoctoral project started in 2013 at Instituto de Engenharia Biomédica (INEB) with the project "Bioprinted celullarized hydrogels for in situ skin regeneration" (FCT Post-doctoral grant) under the supervision of Pedro L. Granja at the Biocarrier - Biomaterials for Multistage Drug & Cell Delivery Group in collaboration with Manchester University, UK.

Since then, she has officially supervised 12 graduate students (1 PhD, 11 Msc) and has been the responsible of tutoring/mentoring the work of 13 graduate students (3 PhD, 10 Msc). She has been involved in obtaining and participating in funded research projects (1 as principal investigator, 2 as a team leader and 5 as PhD team member).

She is now a PhD Junior Researcher at Instituto de Inovação e Investigação em Saúde (i3S) and her major focus in on studying the interplay between bioinspired biomaterials and cells focusing on the development of 3D microenvironments towards the development of Regenerative Medicine strategies.

Over the years she has gained expertise in developing new biomaterial-based strategies for bone and skin tissue engineering using state-of-the art emerging biofabrication techniques, such as extrusion 3D bioprinting, wet-spinning and electrospinning.

She authored 9 articles in international peer-reviewed journals and 2 book chapters. Her work has been disseminated through 21 oral and 15 poster communications in international scientific meetings.

Selected Publications

Marques C.F., Olhero S.M., Torres P.M.C., Abrantes J.C.C., Fateixa S., Nogueira H.I.S., Ribeiro I.A.C., Bettencourt A., Sousa A., Granja P.L., Ferreira J.M.F.,
Novel sintering-free scaffolds obtained by additive manufacturing for concurrent bone regeneration and drug delivery: Proof of concept. Materials Science and Engineering C94:426-436, 2019. [Journal: Article] [CI: 7] [IF: 5,9]
DOI: 10.1016/j.msec.2018.09.050 SCOPUS: 85053772854. .

Pereira R.F., Sousa A., Barrias C.C., Bártolo P.J., Granja P.L.,
A single-component hydrogel bioink for bioprinting of bioengineered 3D constructs for dermal tissue engineering. Materials Horizons5(6):1100-1111, 2018. [Journal: Article] [CI: 16] [IF: 14,4]
DOI: 10.1039/c8mh00525g SCOPUS: 85055847804. .

Neves S.C., Gomes D.B., Sousa A., Bidarra S.J., Petrini P., Moroni L., Barrias C.C., Granja P.L.,
Biofunctionalized pectin hydrogels as 3D cellular microenvironments. Journal of Materials Chemistry B3(10):2096-2108, 2015. [Journal: Article] [CI: 42] [IF: 4,9]
DOI: 10.1039/c4tb00885e SCOPUS: 84923913719. .

Fonseca K.B., Gomes D.B., Lee K., Santos S.G., Sousa A., Silva E.A., Mooney D.J., Granja P.L., Barrias C.C.,
Injectable MMP-sensitive alginate hydrogels as hMSC delivery systems. Biomacromolecules15(1):380-390, 2014. [Journal: Article] [CI: 60] [IF: 5,8]
DOI: 10.1021/bm4016495 SCOPUS: 84892606344. .

Dias J.R., Baptista-Silva S., Sousa A., Oliveira A.L., Bártolo P.J., Granja P.L.,
Biomechanical performance of hybrid electrospun structures for skin regeneration. Materials Science and Engineering C93:816-827, 2018. [Journal: Article] [CI: 5] [IF: 5]
DOI: 10.1016/j.msec.2018.08.050 SCOPUS: 85054091151. .

Bouissou A., Vérollet C., Sousa A., Sampaio P., Wright M., Sunkel C.E., Merdes A., Raynaud-Messina B.,
γ-Tubulin ring complexes regulate microtubule plus end dynamics. Journal of Cell Biology187(3):327-334, 2009. [Journal: Article] [CI: 47] [IF: 9,6]
DOI: 10.1083/jcb.200905060 SCOPUS: 75549091741. .

Sousa A., Reis R., Sampaio P., Sunkel C.E.,
The Drosophila CLASP homologue, mast/orbit regulates the dynamic behaviour of interphase microtubules by promoting the pause state. Cell Motility and the Cytoskeleton64(8):605-620, 2007. [Journal: Article] [CI: 36] [IF: 2,5]
DOI: 10.1002/cm.20208 SCOPUS: 34547120685. .

Dias J.R., Baptista-Silva S., Oliveira C.M.T.d., Sousa A., Oliveira A.L., Bártolo P.J., Granja P.L.,
In situ crosslinked electrospun gelatin nanofibers for skin regeneration. European Polymer Journal95:161-173, 2017. [Journal: Article] [CI: 16] [IF: 3,7]
DOI: 10.1016/j.eurpolymj.2017.08.015 SCOPUS: 85026912199. .

Caldeira J., Sousa A., Sousa D.M., Barros D.,
Extracellular matrix constitution and function for tissue regeneration and repair. Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair:29-72, 2018. [Book: Chapter] [CI: 4]
DOI: 10.1016/B978-0-08-100803-4.00002-4 SCOPUS: 85038852388. .