Where Ideas grow
Bianca Lourenço
Research Scientist

Bianca Lourenço obtained her MSc in Biomedical Engineering from University of Minho and her PhD from University of Porto. During her master research studies at 3B’s Research Group and the Tissue Regeneration Group at University of Twente (The Netherlands), working under the supervision of Prof. João Mano and Dr. Aart van Apeldoorn, respectively, she developed a fundamental study on cell-material interactions using primary cell cultures on bioinspired superhydrophobic surfaces. Afterwards, she joined Dr. Pedro Granja's group at INEB and was awarded with a FCT scholarship to pursue a PhD in biomaterials, nanomedicine and cancer biology fields under his supervision and co-supervision of Dr. Carla Oliveira (i3S/IPATIMUP) and Dr. Claudia Fischbach from Cornell University (USA). Her graduate research in the Biocarrier Group and The Fischbach Lab focused on the development of bioengineered 3D in vitro models through innovative tissue engineering approaches to deconstruct the role of extracellular matrix microenvironment in gastric cancer. Currently, she seeks to develop advanced cell culture methodologies to improve cell-material interactions of polymeric bioabsorbable meshes for regenerative medicine.

Selected Publications

Lourenço B.N., dos Santos T., Oliveira C., Barrias C.C., Granja P.L.,
Bioengineering a novel 3D in vitro model of gastric mucosa for stomach permeability studies. Acta Biomaterialia82:68-78, 2018. [Journal: Article] [CI: 1] [IF: 6,6]
DOI: 10.1016/j.actbio.2018.10.007 SCOPUS: 85055110280. .

Lourenço B.N., Springer N.L., Ferreira D., Oliveira C., Granja P.L., Fischbach C.,
CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling. Integrative biology : quantitative biosciences from nano to macro10(3):145-158, 2018. [Journal: Article] [CI: 8] [IF: 2,8]
DOI: 10.1039/c7ib00179g SCOPUS: 85044245768. .

Dos Santos T.D., Lourenço B.N., Coentro J., Granja P.L.,
Cell-based in vitro models for gastric permeability studies. Concepts and Models for Drug Permeability Studies: Cell and Tissue based In Vitro Culture Models:41-56, 2015. [Book: Chapter] [CI: 4]
DOI: 10.1016/B978-0-08-100094-6.00004-3 SCOPUS: 84966925973. .

Lourenço B.N., Marchioli G., Song W., Reis R.L., van Blitterswijk C.A., Karperien M., van Apeldoorn A., Mano J.F.,
Wettability influences cell behavior on superhydrophobic surfaces with different topographies. Biointerphases7(1-4):1-11, 2012. [Journal: Article] [CI: 57] [IF: 1,9]
DOI: 10.1007/s13758-012-0046-6 SCOPUS: 84868354037. .

Ferreira D.P.S., Lourenço B.N., Rodrigues F.J.O., Mendes P.M.,
Design of efficient wireless links for invasive biomedical microdevices. Proceedings of the 7th IASTED International Conference on Biomedical Engineering, BioMED 20102:27-31, 2010. [Conference Proceeding: Conference Paper]
SCOPUS: 79953832979. .