Where Ideas Grow
Cláudia Machado
Technician

Cláudia graduated in Pathologic, Cytological and Thanatological Anatomy, at School of Allied Health, from Polytechnic Institute of Porto (2015). During this time, she enrolled in several curricular internships in a hospitalar environment (CHSJ, HPH, CHUC), acquiring competences in histology, human anatomy, molecular biology and pathology. In 2019, she obtained her Master degree in Biostatistics and Bioinformatics applied to Health, where she did her master thesis in the proteomic profile of cellular response to biomaterials, for periodontal tissue regeneration, under the supervision of Doctor Cristina Ribeiro at i3S. She acquired competences in bioimage and bioinformatic analysis and statistics. From 2016 to 2021 she was a Research Technician at INEB/i3S. She joined the Histology and Electron Microscopy Service (HEMS) in 2021. 

Selected Publications

Castro A.L., Ribeiro-Machado C., Oliveira C.M., Teixeira G.Q., Neidlinger-Wilke C., Pereira P., Vaz R., Barbosa M.A., Gonçalves R.M.,
Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation. Arthritis Research and Therapy24(1):, 2022. [Journal: Article] [CI: 8] [IF: 4,9]
DOI: 10.1186/s13075-021-02690-w SCOPUS: 85123112980.


Moura S.R., Abreu H., Cunha C., Ribeiro-Machado C., Oliveira C., Barbosa M.A., Marques H., Almeida M.I.,
Circulating micrornas correlate with multiple myeloma and skeletal osteolytic lesions. Cancers13(21):, 2021. [Journal: Article] [CI: 3] [IF: 6,6]
DOI: 10.3390/cancers13215258 SCOPUS: 85117161310.


Ferreira J.R., Teixeira G.Q., Neto E., Ribeiro-Machado C., Silva A.M., Caldeira J., Leite Pereira C., Bidarra S., Maia A.F., Lamghari M., Barbosa M.A., Gonçalves R.M.,
Il-1ß-pre-conditioned mesenchymal stem/stromal cells’ secretome modulates the inflammatory response and aggrecan deposition in the intervertebral disc. European Cells and Materials41:431-453, 2021. [Journal: Article] [CI: 17] [IF: 4,3]
DOI: 10.22203/eCM.v041a28 SCOPUS: 85105699150.


Cunha C., Pereira C.L., Ferreira J.R., Ribeiro-Machado C., Grad S., Santos S.G., Gonçalves R.M.,
Therapeutic strategies for IVD regeneration through hyaluronan/SDF-1-based hydrogel and intravenous administration of MSCs. International Journal of Molecular Sciences22(17):, 2021. [Journal: Article] [CI: 6] [IF: 6,2]
DOI: 10.3390/ijms22179609 SCOPUS: 85114252859.


Cunha C., Teixeira G.Q., Ribeiro-Machado C., Pereira C.L., Ferreira J.R., Molinos M., Santos S.G., Barbosa M.A., Goncalves R.M.,
Modulation of the in vivo inflammatory response by pro-versus anti-inflammatory intervertebral disc treatments. International Journal of Molecular Sciences21(5):, 2020. [Journal: Article] [CI: 15] [IF: 5,9]
DOI: 10.3390/ijms21051730 SCOPUS: 85081025374.


Lourenço A.H., Torres A.L., Vasconcelos D.P., Ribeiro-Machado C., Barbosa J.N., Barbosa M.A., Barrias C.C., Ribeiro C.C.,
Osteogenic, anti-osteoclastogenic and immunomodulatory properties of a strontium-releasing hybrid scaffold for bone repair. Materials Science and Engineering C99:1289-1303, 2019. [Journal: Article] [CI: 54] [IF: 5,9]
DOI: 10.1016/j.msec.2019.02.053 SCOPUS: 85061929662.


Silva A.M., Almeida M.I., Teixeira J.H., Ivan C., Oliveira J., Vasconcelos D., Neves N., Ribeiro-Machado C., Cunha C., Barbosa M.A., Calin G.A., Santos S.G.,
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response. Theranostics8(14):3902-3917, 2018. [Journal: Article] [CI: 10] [IF: 8,1]
DOI: 10.7150/thno.24444 SCOPUS: 85049180465.


Henriques Lourenço A., Neves N., Ribeiro-Machado C., Sousa S.R., Lamghari M., Barrias C.C., Trigo Cabral A., Barbosa M.A., Ribeiro C.C.,
Injectable hybrid system for strontium local delivery promotes bone regeneration in a rat critical-sized defect model. Scientific Reports7(1):, 2017. [Journal: Article] [CI: 40] [IF: 4,1]
DOI: 10.1038/s41598-017-04866-4 SCOPUS: 85023187921.


Pereira C.L., Teixeira G.Q., Ribeiro-Machado C., Caldeira J., Costa M., Figueiredo F., Fernandes R., Aguiar P., Grad S., Barbosa M.A., Goncalves R.M.,
Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling. Scientific Reports6:, 2016. [Journal: Article] [CI: 40] [IF: 4,3]
DOI: 10.1038/srep33836 SCOPUS: 84988672665.