Manuela Brás

Biointerfaces and Nanotechnology

Platform Head

Manuela Brás was born on March 6th, 1972 (Lisboa). She graduated in Metallurgical and Materials Engineering (1995) and obtained her MSc in Biomedical Engineering (2001) both in the Faculdade de Engenharia da Universidade do Porto (FEUP). Her first job was in the mechanical industry (A. Brito Engrenagens, Lda) where she was the head of the Quality department. She started her work at INEB in 1996 with a fellowship provided by the FCT, as a laboratory technician. In 1999, she was hired by INEB. Actually, she is the Head of Biointerfaces and Nanotechnology scientific platform, at i3S. In March of 2023, she obtained her Ph.D. in Biomedical Engineering at FEUP, with the thesis “Mechanobiology of cancer cells using atomic force microscopy”.

Selected Publications

Brás M.M., Sousa A., Cruz T.B., Michalewski J., Leite M., Sousa S.R., Granja P.L., Radmacher M.,

Microrheological comparison of melanoma cells by atomic force microscopy. Journal of Biological Physics:, 2024. [Journal: Article] [IF: 1,8 (*)]
DOI: 10.1007/s10867-023-09648-w SCOPUS: 85182626029.

Brás M., Zemla J., Farré R.,

Tissue Preparation. Mechanics of Cells and Tissues in Diseases: Biomedical Applications: Volume 22:91-104, 2023. [Book: Book Chapter]
DOI: 10.1515/9783110989380-008 SCOPUS: 85152351881.

Brás M.M., Sousa S.R., Carneiro F., Radmacher M., Granja P.L.,

Mechanobiology of Colorectal Cancer. Cancers14(8):, 2022. [Journal: Review] [CI: 3] [IF: 5,2]
DOI: 10.3390/cancers14081945 SCOPUS: 85127970497.

Brás M.M., Cruz T.B., Maia A.F., Oliveira M.J., Sousa S.R., Granja P.L., Radmacher M.,

Mechanical Properties of Colorectal Cancer Cells Determined by Dynamic Atomic Force Microscopy: A Novel Biomarker. Cancers14(20):, 2022. [Journal: Article] [CI: 5] [IF: 5,2]
DOI: 10.3390/cancers14205053 SCOPUS: 85140627715.

Brás M.M., Radmacher M., Sousa S.R., Granja P.L.,

Melanoma in the Eyes of Mechanobiology. Frontiers in Cell and Developmental Biology8:, 2020. [Journal: Review] [CI: 15] [IF: 6,7]
DOI: 10.3389/fcell.2020.00054 SCOPUS: 85081104695.

Selvaggio G., Canato S., Pawar A., Monteiro P.T., Guerreiro P.S., Manuela Brás M., Janody F., Chaouiya C.,

Hybrid epithelial–mesenchymal phenotypes are controlled by microenvironmental factors. Cancer Research80(11):2407-2420, 2020. [Journal: Article] [CI: 29] [IF: 12,7]
DOI: 10.1158/0008-5472.CAN-19-3147 SCOPUS: 85085904168.

Seabra C.L., Nunes C., Brás M., Gomez-Lazaro M., Reis C.A., Gonçalves I.C., Reis S., Martins M.C.L.,

Lipid nanoparticles to counteract gastric infection without affecting gut microbiota. European Journal of Pharmaceutics and Biopharmaceutics127:378-386, 2018. [Journal: Article] [CI: 28] [IF: 4,7]
DOI: 10.1016/j.ejpb.2018.02.030 SCOPUS: 85044023662.

Felgueiras H.P., Murthy N.S., Sommerfeld S.D., Brás M.M., Migonney V., Kohn J.,

Competitive Adsorption of Plasma Proteins Using a Quartz Crystal Microbalance. ACS Applied Materials and Interfaces8(21):13207-13217, 2016. [Journal: Article] [CI: 42] [IF: 7,5]
DOI: 10.1021/acsami.5b12600 SCOPUS: 84973402590.

Sousa S.R., Manuela Brás M., Moradas-Ferreira P., Barbosa M.A.,

Dynamics of fibronectin adsorption on TiO ₂ surfaces. Langmuir23(13):7046-7054, 2007. [Journal: Article] [CI: 66] [IF: 4]
DOI: 10.1021/la062956e SCOPUS: 34547242561.