Where Ideas Grow
Mariana Nunes
PhD Student

I am currently a PhD student in Differentiation and Cancer Group and in the Doutoral Progrma in Pathology and Molecular Genetic in the Institute of Biomedical Sciences Abel Salazar of the University of Porto.

In 2019, I obtained a master’s degree in Oncology by Institute of Biomedical Sciences Abel Salazar from University of Porto. My Master´s Dissertation “First line drug testing in ovarian cancer cell lines manipulated for Mesothelin expression", was performed under scientific supervision of Doctor Sara Ricardo and Doctor Leonor David in Differentiation and Cancer Group at i3S. 

In 2016, I completed by Bachelor´s degree in Biology at the University of Aveiro with an internship in Genomics Unit at Biocant (University of Coimbra).

Selected Publications

Nunes M., Abreu M.H., Bartosch C., Ricardo S.,
Recycling the purpose of old drugs to treat ovarian cancer. International Journal of Molecular Sciences21(20):1-24, 2020. [Journal: Review] [CI: 12] [IF: 5,9]
DOI: 10.3390/ijms21207768 SCOPUS: 85093658021.


Nunes M., Silva P.M.A., Coelho R., Pinto C., Resende A., Bousbaa H., Almeida G.M., Ricardo S.,
Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein. Frontiers in Oncology11:, 2021. [Journal: Article] [CI: 9] [IF: 5,7]
DOI: 10.3389/fonc.2021.752127 SCOPUS: 85118608070.


Nunes M., Pacheco F., Coelho R., Leitão D., Ricardo S., David L.,
Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer. International Journal of Molecular Sciences23(3):, 2022. [Journal: Article] [IF: 5,6]
DOI: 10.3390/ijms23031016 SCOPUS: 85122857215.


Coelho R., Ricardo S., Amaral A.L., Huang Y.L., Nunes M., Neves J.P., Mendes N., López M.N., Bartosch C., Ferreira V., Portugal R., Lopes J.M., Almeida R., Heinzelmann-Schwarz V., Jacob F., David L.,
Regulation of invasion and peritoneal dissemination of ovarian cancer by mesothelin manipulation. Oncogenesis9(6):, 2020. [Journal: Article] [CI: 27] [IF: 7,5]
DOI: 10.1038/s41389-020-00246-2 SCOPUS: 85087314253.


Félix C., Libório S., Nunes M., Félix R., Duarte A.S., Alves A., Esteves A.C.,
Lasiodiplodia theobromae as a producer of biotechnologically relevant enzymes. International Journal of Molecular Sciences19(2):, 2018. [Journal: Article] [CI: 19] [IF: 4,2]
DOI: 10.3390/ijms19020029 SCOPUS: 85041037451.


Pinto C., Custódio V., Nunes M., Songy A., Rabenoelina F., Courteaux B., Clément C., Gomes A.C., Fontaine F.,
Understand the potential role of aureobasidium pullulans, a resident microorganism from grapevine, to prevent the infection caused by Diplodia seriata. Frontiers in Microbiology9(DEC):, 2018. [Journal: Article] [CI: 37] [IF: 4,3]
DOI: 10.3389/fmicb.2018.03047 SCOPUS: 85058299482.


Nunes M., Silva P.M.A., Coelho R., Pinto C., Resende A., Bousbaa H., Almeida G.M., Ricardo S.,
Corrigendum: Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein(Front. Oncol., (2021), 11, (752127), 10.3389/fonc.2021.752127). Frontiers in Oncology12:, 2022. [Journal: Erratum] [IF: 4,7]
DOI: 10.3389/fonc.2022.853608 SCOPUS: 85124947543.


Magalhães A.C., Ricardo S., Moreira A.C., Nunes M., Tavares M., Pinto R.J., Gomes M.S., Pereira L.,
InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays. Pathogens11(3):, 2022. [Journal: Article] [CI: 3] [IF: 3,7]
DOI: 10.3390/pathogens11030313 SCOPUS: 85126676736.


Duarte D., Nunes M., Ricardo S., Vale N.,
Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action. Biomolecules12(10):, 2022. [Journal: Article] [CI: 8] [IF: 5,5]
DOI: 10.3390/biom12101490 SCOPUS: 85140479665.


Nunes M., Duarte D., Vale N., Ricardo S.,
Pitavastatin and Ivermectin Enhance the Efficacy of Paclitaxel in Chemoresistant High-Grade Serous Carcinoma. Cancers14(18):, 2022. [Journal: Article] [CI: 6] [IF: 5,2]
DOI: 10.3390/cancers14184357 SCOPUS: 85138730639.