Where Ideas grow

19th Portugaliæ Genetica
Phenotypic Manifestation of Genetic Heterogeneity

12-13 March 2020 | i3S, Porto, Portugal


The 19th Edition of Portugaliæ Genetica is devoted to the broad theme "Phenotypic Manifestation of Genetic Heterogeneity" and will have a transversal programme covering exciting topics bridging population genetics, evolution and functional genomics with health applications. In particular, it will cover inter and intra-species genetic diversity and its impact in diseases such as cancer, autism and neurodegenerative diseases; the role of genome evolution in phenotypic outcomes and interspecies bridging in disease modelling. The event hopes to contribute to the promotion of collaboration between researchers across these fields.



The meeting will be held at i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, in Auditorium Corino de Andrade.


The i3S consortium, headed by the UPorto, brings together four institutions and researchers from several schools of the UPorto, thus consolidating an extensive collaboration between all institutions that spans many years.
I3S stems from the long-term collaboration between IBMC, INEB and IPATIMUP and encompasses joint projects, co-supervision of PhD students, sharing of large equipment and employment of research staff under coordinated policies. Six schools of the UPorto (FMUP, ICBAS, FMDUP, FCUP, FEUP and FFUP) and three hospitals (CH S João, CH Porto and IPO) also contribute to the activities of i3S. This wide participation of schools, research institutions and hospitals in a research institute is unique in Portugal and is a valuable asset for science and technology development, while creating an environment that feeds real breakthrough research and translation of discoveries into the clinic. The new building - completed in 2015 - is also a key element in the creation of this vibrant environment. This intricate network that is i3S focuses on three Integrative Programs: Cancer, Host Response and Interaction, and Neurobiology and Neurologic Disease.



Rua Alfredo Allen, 208; 4200-135 Porto, Portugal
Tel: +351 220 408 800 | Site: http://www.i3s.up.pt/ | E-mail: events@i3s.up.pt
GPS coordinates: 41º 10' 30.008'' N, 8º 36' 12.488'' W.


Organizing Committee (i3S/Ipatimup):
Iva Gomes | Manuela Oliveira | Mónica Marques | Verónica Gomes


Scientific Committee (i3S/Ipatimup):
Iva Gomes | Luísa Azevedo


Invited Scientific Committee (i3S/IBMC):
Elsa Logarinho | José Bessa


Preliminary Program and confirmed speakers


Thursday | 12th March 2019

SESSION 1 Phenotypic outcomes of genome evolution

Manuel Irimia (CRG, Barcelona, Spain)

Phenotypes Lost and the Anthropocene
Filipe Castro (CIIMAR, Porto, Portugal)

Genetic and environmental determinants of phenotypic variation in complex traits
Patrícia Beldade (Faculdade de Ciências da Universidade de Lisboa e Instituto Gulbenkian de Ciência, Portugal)


SESSION 2 Intra-species heterogeneity

Genomic evolution of cancer models: Perils and opportunities
Uri Ben-David (Tel Aviv University, Israel)

Pedro Esteves (CIBIO-InBIO, Porto, Portugal)
Albano Beja-Pereira (CIBIO-InBIO)



Friday | 13th March 2019

SESSION 3 Impact of genetic heterogeneity in diseases

Angel Carracedo (University of Santiago de Compostela, Spain)
José Carlos Machado (IPATIMUP/i3S, Porto, Portugal)

Rodent malaria models: Insights into parasite biology and implications on vaccines design
Joana Tavares (i3S)


SESSION 4 Interspecies bridging in disease modeling

Zebrafish as a Model in the Study of Human Diseases
Laura Sanchéz (University of Santiago de Compostela, Spain)

Drug and target discovery for neurodegenerative diseases using a multi-species approach
Patricia Maciel (University of Minho, Braga, Portugal)

Quality and validity in animal research
Anna Olsson (i3S)


Abstract Submission

The call for abstracts will be open until 3rd of February (notification of acceptance until the 18th of February).

The meeting will include poster sessions and the selection of 4 abstracts for short oral communications as part of the program, during which contributors will have the opportunity to introduce and attract attention to their research. During submission of abstracts, candidates can select their preference for oral or poster presentation format.


The participants should use the layout provided here:


The best poster will be awarded prize money sponsored by Pfizer.

Abstracts Guidelines:
- Title is limited to 150 characters (including spaces)
- Abstracts are limited to 1500 characters (including spaces; authors and affiliations excluded) - Define all non-standard abbreviations at first use
- Images cannot be included in the abstract
- Abstracts should be submitted through the web interface


Registration fee includes coffee breaks, lunches and conference material.

i3S members & students - €60
External members - €80


Registration Deadline: 21st February 2020
Payment Deadline: 24th February 2020













Events Management Unit | Rua Alfredo Allen 208 | 4200-135 Porto, Portugal
Email: events@i3s.up.pt | Tel: +351 220 408 800