PhasAGE Kick-Off Meeting
5th February 2021 | ONLINE EVENT
Liquid-liquid phase separation (LLPS) has recently emerged as a fundamental strategy for intracellular organization with relevance for the regulation of multiple biological processes, including DNA replication and repair, transcription, signaling and synapse formation. Importantly, aberrant phase transitions have been consistently associated with diseases such as cancer and neurodegeneration.
The Twinning project “PhasAGE: Excellence Hub on Phase Transitions in Aging and Age-Related Disorders” aims at strengthening the excellence, knowledge and innovation potential of i3S in the emerging field of biomolecular phase transitions. The consortium, headed by i3S, includes recognized experts on biological phase separation from Belgium (Peter Tompa and Ludo van Den Bosch, VIB), Spain (Salvador Ventura, Universitat Autònoma de Barcelona) and Italy (Silvio Tosatto, Università di Padova).
We would like to invite you to attend the public session of the Kick-off Meeting on February 5 2021.
5th February 2021
PhasAGE Closed Session
(PhasAGE Participants Only)
10:00 to 13:00 CET (Belgium, Spain, Italy, France)
9:00 to 12:00 GMT (Portugal, United Kingdom
PhasAGE Public Session
14:15 to 17:30 CET (Belgium, Spain, Italy, France)
13:15 to 16:30 GMT (Portugal, United Kingdom)
CET Time (GMT=CET-1)
14:15-14:30 - Welcome and overview of PhasAGE project (Sandra Ribeiro – Project Coordinator)
14:30-15:10 - Plenary Talk: Molecular mechanisms controlling phase separation of neurodegeneration-linked RNA-binding proteins (Dorothee Dormann, LMU Muenchen, Germany)
15:10-15:40 - Kinetics and nucleation of liquid-liquid phase separation (Peter Tompa, VIB, Belgium)
15:40-16:00 - Coffee Break
16:00-16:30 - Role of phase separation and stress granule dynamics in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (Ludo Van Den Bosch, VIB, Belgium)
16:30-17:00 - Role of alternative splicing in phase separation and pathogenic aggregation of hnRNPDL (Salvador Ventura, UAB, Spain)
17:00-17:30 - Protein interactions in droplets (Monika Fuxreiter, UniPD, Italy)
Registration is free but mandatory.
Registration deadline: 4th February 2021, at 15:00 (GMT)
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