Where Ideas grow

18th Portugaliæ Genetica
Genetic Diversity in Structure and Regulation

22 & 23 March 2018

Welcome to the 18th Edition of Portugaliæ Genetica!


This year's edition is devoted to the broad theme "Genetic diversity in structure and regulation" and we have prepared a transversal programme covering exciting topics bridging population genetics, evolution and functional genomics, including the impact of genetic diversity on health and disease. We truly hope this event will contribute to promote collaboration between researchers across these fields!


The Organizing Committee

Abstract Book | Download PDF 



The meeting will be held at i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, in Auditorium Corino de Andrade.



The i3S consortium, headed by the UPorto, brings together four institutions and researchers from several schools of the UPorto, thus consolidating an extensive collaboration between all institutions that spans many years.
I3S stems from the long-term collaboration between IBMC, INEB and IPATIMUP and encompasses joint projects, co-supervision of PhD students, sharing of large equipment and employment of research staff under coordinated policies. Six schools of the UPorto (FMUP, ICBAS, FMDUP, FCUP, FEUP and FFUP) and three hospitals (CH S João, CH Porto and IPO) also contribute to the activities of i3S. This wide participation of schools, research institutions and hospitals in a research institute is unique in Portugal and is a valuable asset for science and technology development, while creating an environment that feeds real breakthrough research and translation of discoveries into the clinic. The new building - completed in 2015 - is also a key element in the creation of this vibrant environment. This intricate network that is i3S focuses on three Integrative Programs: Cancer, Host Interaction and Response, and Neurobiology and Neurologic Disorders.



Rua Alfredo Allen, 208; 4200-135 Porto, Portugal
Tel: +351 220 408 800 | Site: http://www.i3s.up.pt/ | E-mail: events@i3s.up.pt
GPS coordinates: 41º 10' 30.008'' N, 8º 36' 12.488'' W.



Events Management Office
Rua Alfredo Allen 208 | 4200-135 Porto, Portugal
Email: events@i3s.up.pt
Tel: +351 220 408 811 | Cell/ Mobile: +351 964 013 945


Scientific and Organizing Committee
Luisa Azevedo
Maria João Prata
Pedro Rodrigues

João Morais Cabral

Sandra Martins
Manuela Oliveira



Genetic diversity in structure and regulation


Thursday | 22nd March 2018


09.00 Registration


09.30 Opening session 


SESSION 1 Genome Evolution

Chair: Alexandra Lopes | i3S/ Ipatimup


09.45 Sex chromosome evolution in non-model organisms
Beatriz Vicoso | Institute of Science and Technology Austria, IST Austria


10.35 Coffee break


11.00 The feedback loop between ageing and aneuploidy
Elsa Logarinho | i3S/ IBMC, Porto, Portugal


11.30 When secondary comes first: the role of DNA secondary structures in mitochondrial genomes
Filipe Pereira | CIIMAR, Porto, Portugal


12.00 Mitochondrial DNA evolutionary breakpoints are associated with non-B DNA conformations

João Carneiro | CIIMAR, Porto, Portugal

12.10 Contrasting molecular adaption in Slo1 and Slo3 channel subfamilies

Alberto Vicens | University of Vigo, Spain


12.20 Poster session and Lunch


SESSION 2 Genome Regulation

Chair: Miguel Arenas | University of Vigo, Spain


14.30 The impact of genetic variation on protein post-translation regulation in cancer
Pedro Beltrão | EMBL-EBI, Wellcome Genome Campus, Cambridge, UK


15.20 Exploring the role of non-coding mutations in pancreatic diseases through the analysis of the zebrafish pancreas regulome
José Bessa | i3S/ IBMC, Porto, Portugal


15.50 Coffee break


16.20 Chasing the elusive origins of novel enhancers
Élio Sucena | IGC and FCUL, Oeiras, Portugal


16.50 A non-coding repeat insertion in DAB1 causes the neurodegenerative disease SCA37
Isabel Silveira | i3S/ IBMC, Porto, Portugal



Friday | 23rd March 2018


SESSION 3 Genome Interaction and Response

Chair: Maria João Prata | i3S/ Ipatimup


09.30 Genetic and evolutionary determinants of immune variability: a population genetics view of the response to infection
Maxime Rotival | Institut Pasteur, Paris, France


10.20 Coffee break


10.45 An interactomics approach to DJ-1 function and role in oxidative stress
Bruno Manadas | CNC, University of Coimbra, Portugal


11.15 Function and dynamics of low complexity regions in proteins
Sandra Macedo-Ribeiro | i3S/ IBMC, Porto, Portugal


11.45 Accounting for Protein Stability in Sequence Evolution: Applications to Phylogenetics

Miguel Arenas | University of Vigo, Spain

11.55 Metagenomic composition analysis of ancient DNA samples

Diogo Pratas | University of Aveiro, Portugal


12.05 Poster session and Lunch


SESSION 4 Genome Legacy

Chair: António Amorim | i3S/ Ipatimup


14.00 Archaeovirology - viruses as a window to the past
Anti Sajantilla | University of Helsinki, Finland


14.50 RADseq a cheap and promising NGS tool to access the evolutionary history of livestock populations
Albano Beja-Pereira | CIBIO-InBIO and FCUP, Porto, Portugal


15.20 Coffee break


15.50 Diagnosis of inborn errors of metabolism: merging genomics with metabolomics
Hugo Rocha | INSA, Porto, Portugal


16.20 Genetic diversity in Mycobacterium tuberculosis: linking genotypes to phenotypes
Margarida Santos Saraiva | i3S/ IBMC, Porto, Portugal


16.50 Closing session


Abstract Submission

The call for abstracts will be open until 2nd March 2018 (notification of acceptance on 9th March 2018).


The meeting will include 4 selected talks and poster sessions as part of the program, during which contributors will have the opportunity to introduce and attract attention to their work. Candidates can select their preference for an oral or poster presentation.


The participants should use the layout provided here:


Abstracts Guidelines:
- Title is limited to 150 characters (including spaces).
- Abstracts are limited to 1500 characters (including spaces; authors and affiliations excluded).
- Define all non-standard abbreviations at first use.
- Images can not be included in the abstract.
- Abstracts should be submitted through the web interface.



i3S members & students - €50
External members - €80


Registration Deadline: 14th March 2018

Payment Deadline: 16th March 2018

Registration fee includes coffee breaks, lunch and conference material.




Payment Details
Please identify your name clearly and the Registration ID when ordering the transfer and send us a copy of the transfer receipt to events@i3s.up.pt.
The receipts will be issued only if requested and amendments will not be accepted.
Full payment of costs should be made in EURO (payments in any other currency will not be accepted).
Currency exchanges or bank fees have to be paid by the registrant. In case of cancellation, the registration fee will not be refunded.



Bank Details
Bank Holder Name: IPATIMUP
Bank: Santander Totta
Address: Rua Damião de Góis, 301; 4050- 227 Porto
IBAN: PT50 0018 0001 0020 1600 4406 3
NIB: 0018 0001 0020 1600 4406 3
Account number: 000100201600440
IPATIMUP VAT number: 502 246 308



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