Where Ideas grow

Organoids and other advanced tissue models for biomedical research

20 September 2018 | Auditorium Corino de Andrade, i3S


This meeting addresses a key issue in today’s biomedical research: how non-animal model systems can be developed to meet the needs for translationally relevant research in the era of precision and personalized medicine, whilst at the same time accounting for societal pressure to replace animal experiments.


Coordinators: Anna Olsson and Margarida Saraiva




10.00 Opening

Pedro Rodrigues, Vice-Rector for Research and Innovation, University of Porto


10.10 - 10.50 Presentation by

Roos Masereeuw, Professor of Experimental Pharmacology, Utrecht University


10.50 - 11.10 Coffee break


11.10 - 12.10 Presentations by

Cristina Barrías, Coordinator of the Bioengineered 3D Microenvironments group, i3S

Margarida Saraiva, Coordinator of the Immune Regulation group, i3S


12.10 - 13.00 Roundtable with invited industry and policymaker representatives

Moderator: Anna Olsson, i3S


Roos Masereeuw

Professor Roos Masereeuw is an expert on developing humanized in vitro systems that functionally mimic (patients) organs, which includes the use of innovative technologies for 3-dimensional organ cultures such as microfluidics (organs-on-chip technology). These experimental tools should aid in translating molecular interactions into therapeutic effects. Based on the unique, patented, human renal cell lines with a high predictive value for drug and waste product transport and metabolism, her team is developing a bioartificial kidney, a kidney-on-a-chip device suitable for in vitro toxicity testing and research into the renal tubular secretion and reabsorption machinery. She holds the chair in Experimental Pharmacology at the University of Utrecht.

Cristina Barrias

Dr. Cristina Barrias works in biomaterials for regenerative medicine, at the bioengineering/biomedicine interface. Her research is focused on the development of molecularly-designed hydrogels as extracellular matrix mimics, and on their application as advanced vehicles for cell-based regenerative therapies and as 3D cell culture models. She completed her Ph.D. at the University of Porto in 2005 and in 2009 she was hired as a researcher at INEB, where she is the deputy coordinator of the Biocarrier group since 2014.

Margarida Saraiva

Dr. Margarida Saraiva received a Ph.D. from the University of Cambridge and pursued her post-doctoral studies at the National Institute for Medical Research (NIMR), Mill Hill, London, both in the area of the immune response to pathogens. In mid-2007, Margarida Saraiva returned to Portugal and joined ICVS-3B’s (Univ. of Minho) to set up her own research program, focused on the study of tuberculosis (TB). In 2013, Margarida Saraiva was awarded a FCT- associated investigator position and in mid-2015, secured a group leader position in a major research institute in Porto, IBMC-i3S, where her team is continuing our research lines on immune regulation by IL-10 and M. tuberculosis.


Registration until 3rd September 2018 | Payment deadline: 3rd September 2018



UP members (20 €)

Other participants (30 €)


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Email: events@i3s.up.pt | Tel: +351 220 408 811