Where Ideas Grow
Paulo Silva
I finished my graduation in Applied Biology at the University of Minho, Braga, Portugal in 2002, where I worked with the wine contamination yeast Brettanomyces bruxellensis and published the results in the American Journal of Enology and Viticulture, awarded the Best Enology Paper in 2005 by the American Society of Enology and Viticulture. I then pursued a Ph.D. at the Department of Biology, University of Minho, Braga, Portugal, focusing on biochemical and molecular mechanisms underlying salt stress tolerance in the olive tree (Olea europaea) and poplar (Populus euphratica), which resulted in the publication of 8 papers in peer-reviewed journals. I have always been passionate about both computers and biology since early childhood. I started exploring computers at a young age on the Sinclair ZX Spectrum, and continued throughout the years by self-teaching several programming languages (such as BASIC, Pascal and C), as well as playing with various operating systems, including Linux. In 2010, to bring together my passion for biology and computers, I enrolled on a M.Sc. in Bioinformatics at the University of Leicester, UK. My research project was undertaken at the European Bioinformatics Institute in Cambridge, UK, in collaboration with the NIH-NHGRI (National Human Genome Research Institute, part of the National Institutes of Health, USA), where I developed an ontology based on the annotations present in the Genome-Wide Association Studies Online Catalogue of the NHGRI, and was awarded the AstraZeneca Prize for Best Independent Research Project at the end of my training. Currently, I am working as a bioinformatician at the Centre for Predictive and Preventive Genetics (CGPP) at i3s, where I am optimizing the analysis of NGS data in the context of genetic testing and diagnosis of rare neurological disorders.