Ana Spencer
NanoBiomaterials for Targeted Therapies
PhD Student
Ana Spencer obtained a BSc in Biochemistry (2015) and MSc in Molecular Genetics and Biomedicine (2017) from the Faculty of Sciences and Technology of the New University of Lisbon. Now, she is a PhD student under the supervision of Dr. Ana Paula Pêgo and Dr Victoria Leiro, focused on the development of a new targeted delivery vector for spinal cord injury.
Selected Publications
Summers H.D., Gomes C.P., Varela-Moreira A., Spencer A.P., Gomez-Lazaro M., Pêgo A.P., Rees P.,
Leiro V., Spencer A.P., Magalhães N., Pêgo A.P.,
Spencer A.P., Torrado M., Custódio B., Silva-Reis S.C., Santos S.D., Leiro V., Pêgo A.P.,
Pereira Gomes C., Leiro V., Ferreira Lopes C.D., Spencer A.P., Pêgo A.P.,
Leiro V., Garcia J.P., Moreno P.M.D., Spencer A.P., Fernandez-Villamarin M., Riguera R., Fernandez-Megia E., Paula Pêgo A.,
Data-driven modeling of the cellular pharmacokinetics of degradable chitosan-based nanoparticles. Nanomaterials11(10):, 2021. [Journal: Article] [CI: 2] [IF: 5,7]
DOI: 10.3390/nano11102606 SCOPUS: 85116167889.
DOI: 10.3390/nano11102606 SCOPUS: 85116167889.
Leiro V., Spencer A.P., Magalhães N., Pêgo A.P.,
Versatile fully biodegradable dendritic nanotherapeutics. Biomaterials281:, 2022. [Journal: Article] [CI: 4] [IF: 14]
DOI: 10.1016/j.biomaterials.2021.121356 SCOPUS: 85122615698.
DOI: 10.1016/j.biomaterials.2021.121356 SCOPUS: 85122615698.
Spencer A.P., Torrado M., Custódio B., Silva-Reis S.C., Santos S.D., Leiro V., Pêgo A.P.,
Breaking barriers: Bioinspired strategies for targeted neuronal delivery to the central nervous system. Pharmaceutics12(2):, 2020. [Journal: Review] [CI: 14] [IF: 6,3]
DOI: 10.3390/pharmaceutics12020192 SCOPUS: 85079861582.
DOI: 10.3390/pharmaceutics12020192 SCOPUS: 85079861582.
Pereira Gomes C., Leiro V., Ferreira Lopes C.D., Spencer A.P., Pêgo A.P.,
Fine tuning neuronal targeting of nanoparticles by adjusting the ligand grafting density and combining PEG spacers of different length. Acta Biomaterialia78:247-259, 2018. [Journal: Article] [CI: 18] [IF: 6,6]
DOI: 10.1016/j.actbio.2018.08.005 SCOPUS: 85051662392.
DOI: 10.1016/j.actbio.2018.08.005 SCOPUS: 85051662392.
Leiro V., Garcia J.P., Moreno P.M.D., Spencer A.P., Fernandez-Villamarin M., Riguera R., Fernandez-Megia E., Paula Pêgo A.,
Biodegradable PEG-dendritic block copolymers: Synthesis and biofunctionality assessment as vectors of siRNA. Journal of Materials Chemistry B5(25):4901-4917, 2017. [Journal: Article] [CI: 17] [IF: 4,8]
DOI: 10.1039/c7tb00279c SCOPUS: 85021637380.
DOI: 10.1039/c7tb00279c SCOPUS: 85021637380.