Tiago Dantas started his scientific career in 2007 as an Erasmus student investigating centrosome biology in the lab of Prof. Ciaran Morrison at the National University of Ireland in Galway. Tiago was then awarded a fellowship from FCT to continue his work in Prof. Morrison’s lab as a PhD student. His dissertation focused on the crosstalk between centrosomal proteins and the DNA damage response.
After receiving his PhD in 2012, Tiago joined the lab of Prof. Richard Vallee at Columbia University in New York, where he was funded by the AHA/ASA to study the importance of ciliogenesis and molecular motors in neural stem cell proliferation. In addition, he studied the involvement of Dyneins in human disease.
In 2018, Tiago joined IBMC/i3S to start his own line of research, focusing on the poorly characterized form of Dynein, known as Dynein-2, which is essential for retrograde intraflagellar transport inside cilia and many cell signaling pathways. His team is also interested in understanding the ciliary-dependent signaling mechanisms that regulate cell cycle progression and proliferation of neural stem cells during brain development.
- Carla Abreu, PhD (Assistant Investigator)
- José Bernardo Gama, PhD (Postdoc)
- Diogo Rodrigues, MSc (PhD student)
- Vanessa Teixeira (Co-supervised PhD student from the Gassmann Lab)
- Ana Rita Castro, BSc (Master Student)
- Tiago Xavier Ribeiro, MSc (Researcher)
- Maria João Castro, BSc (Master Student)
- André Sousa, BSc (PhD candidate)
- Joana Gonçalves, BSc (Visiting Student)
Alumni Team members:
- Carmen Vieira, BSc, MSc (Master project 2018-2019)
- Telma Oliveira BSc (Final year project - 2018)
- Marcos Machado, BSc (Visiting Student 2020)
- Luísa Fonseca, BSc (Final year project-2020)
Current Project Funding:
TD was initially supported by the Porto Neurosciences and Neurologic Disease Research Initiative at I3S (Norte-01-0145-FEDER-000008)
TD is also an Editorial Board member of the Communications Biology Journal (Nature Publishing Group): https://www.nature.com/commsbio/about/editorial-board#Dantas
DOI: 10.1016/j.devcel.2020.03.011 SCOPUS: 85083116287.
Gonçalves J.C., Dantas T.J., Vallee R.B.,
DOI: 10.1083/jcb.201806112 SCOPUS: 85062391953.
Doobin D.J., Kemal S., Dantas T.J., Vallee R.B.,
DOI: 10.1038/ncomms12551 SCOPUS: 84984636132.
Doobin D.J., Dantas T.J., Vallee R.B.,
DOI: 10.1080/15384101.2016.1252591 SCOPUS: 84995519777.
Dantas T.J., Carabalona A., Hu D.J.K., Vallee R.B.,
DOI: 10.1002/cm.21293 SCOPUS: 84962588361.
Yi J., Khobrekar N.V., Dantas T.J., Zhou J., Vallee R.B.,
DOI: 10.1016/bs.mcb.2015.06.014 SCOPUS: 84940704542.
Baffet A.D., Carabalona A., Dantas T.J., Doobin D.D., Hu D.J., Vallee R.B.,
DOI: 10.1016/bs.mcb.2015.06.013 SCOPUS: 84940676248.
Taylor S.P., Dantas T.J., Duran I., Wu S., Lachman R.S., Nelson S.F., Cohn D.H., Vallee R.B., Krakow D., Bamshad M.J., Shendure J., Nickerson D.A.,
DOI: 10.1038/ncomms8092 SCOPUS: 84935907084.
Daly O.M., Gaboriau D., Karakaya K., King S., Dantas T.J., Lalor P., Dockery P., Krämer A., Morrison C.G.,
DOI: 10.1242/jcs.186221 SCOPUS: 84968735321.
Conroy P.C., Saladino C., Dantas T.J., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.4161/cc.21986 SCOPUS: 84868020395.
Dantas T.J., Daly O.M., Conroy P.C., Tomas M., Wang Y., Lalor P., Dockery P., Ferrando-May E., Morrison C.G.,
DOI: 10.1371/journal.pone.0068487 SCOPUS: 84879770210.
Wang Y., Dantas T.J., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.4161/cc.23516 SCOPUS: 84874594469.
Dantas T.J., Wang Y., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.1083/jcb.201012093 SCOPUS: 79955516456.
de Carvalho A.L.R.T., Strikoudis A., Liu H.Y., Chen Y.W., Dantas T.J., Vallee R.B., Correia-Pinto J., Snoeck H.W.,
DOI: 10.1242/dev.171652 SCOPUS: 85060395959.