Tiago Dantas started his scientific career in 2007 as an Erasmus student investigating centrosome biology in the lab of Prof. Ciaran Morrison at the National University of Ireland in Galway. Tiago was then awarded a fellowship from FCT to continue his work in Prof. Morrison’s lab as a PhD student. His dissertation focused on the crosstalk between centrosomal proteins and the DNA damage response.
After receiving his PhD in 2012, Tiago joined the lab of Prof. Richard Vallee at Columbia University in New York, where he was funded by the AHA/ASA to study the importance of ciliogenesis and molecular motors in neural stem cell proliferation. In addition, he studied the involvement of Dyneins in human disease.
In 2018, Tiago joined IBMC/i3S to start his own line of research, focusing on the poorly characterized form of Dynein, known as Dynein-2, which is essential for retrograde intraflagellar transport inside cilia and many cell signaling pathways. His team is also interested in understanding the ciliary-dependent signaling mechanisms that regulate cell cycle progression and proliferation of neural stem cells during brain development.
- Carla Manuela Castro Abreu, PhD (Associate Researcher)
- Diogo Rodrigues, MSc (PhD student)
- Ana Rita De-Castro, MSc (PhD student)
- Tiago Xavier Ribeiro, MSc (PhD student)
- Vanessa Teixeira, (Co-supervised PhD student from the Gassmann Lab)
- Célia Azevedo Soares, MD, PhD (Clinical Genetics and Neurodevelopment expert)
- Maria João De-Castro, BSc, MSc (PhD candidate)
- Francisco Santos, BSc, MSc (PhD candidate)
- Luísa Fonseca, BSc (Master Student)
- Francisca Bryant-Jorge Dias BSc (Master Student)
- Maria Francisca Sousa (Bachelor Student - Final year project)
Alumni Team members:
- Carmen Vieira, BSc, MSc (Master project 2018-2019)
- Telma Oliveira BSc (Final year project - 2018)
- Marcos Machado, BSc (Visiting Student 2020)
- José Bernardo Gama, PhD (Postdoc 2019-2020)
- Joana Gonçalves, BSc (Visiting Student 2020-2021)
- Mariana Sousa, BSc (Summer Student 2022)
FCT projects: 2022.01955.PTDC and 2022.01964.PTDC
Individual positions funded: CEECIND/00771/2017 (six-year contract) to T.D., CEECIND/01985/2018 (six-year contract) to C.A., SFRH/BD/143985/2019 to D.R., 2021.04761.BD to T.R., UI/BD/152865/2022 to A.C. and BIIverao/i3S/18072207/2022 to M.S.
FCT project POCI-01-0145-FEDER-029471
In 2018, TD was also supported by the Porto Neurosciences and Neurologic Disease Research Initiative at I3S (Norte-01-0145-FEDER-000008)
Since 2018, TD is an Editorial Board member of the Communications Biology Journal (Nature Publishing Group): https://www.nature.com/commsbio/about/editorial-board#Dantas
TD edited and organized the “Centrosomes and Cilia” collection, which is now online at Communications Biology: https://www.nature.com/collections/iadheaabic
Since 2020, TD is an Editorial Board Member of the journal Frontiers in Cellular Neuroscience
Since 2018, TD is an Invited Professor at the Faculty of Medicine of the University of Porto, where he teaches the Neurodevelopment class in the Neurobiology Masters Degree
Selected as an expert by the EU Commission to evaluate Marie S. Curie Actions (Postdoctoral fellowship applications) in 2021 and 2022
Examiner/evaluating member of the Jury in the defense of 6 Master and 2 PhD theses
DOI: 10.1083/jcb.202010178 SCOPUS: 85123025569.
Abreu C.M.C., Dantas T.J.,
DOI: 10.1038/s42003-021-02243-6 SCOPUS: 85107421637.
DOI: 10.1038/s42003-020-01519-7 SCOPUS: 85098475975.
Khobrekar N.V., Quintremil S., Dantas T.J., Vallee R.B.,
DOI: 10.1016/j.devcel.2020.03.011 SCOPUS: 85083116287.
Gonçalves J.C., Dantas T.J., Vallee R.B.,
DOI: 10.1083/jcb.201806112 SCOPUS: 85062391953.
Doobin D.J., Kemal S., Dantas T.J., Vallee R.B.,
DOI: 10.1038/ncomms12551 SCOPUS: 84984636132.
Doobin D.J., Dantas T.J., Vallee R.B.,
DOI: 10.1080/15384101.2016.1252591 SCOPUS: 84995519777.
Dantas T.J., Carabalona A., Hu D.J.K., Vallee R.B.,
DOI: 10.1002/cm.21293 SCOPUS: 84962588361.
Yi J., Khobrekar N.V., Dantas T.J., Zhou J., Vallee R.B.,
DOI: 10.1016/bs.mcb.2015.06.014 SCOPUS: 84940704542.
Baffet A.D., Carabalona A., Dantas T.J., Doobin D.D., Hu D.J., Vallee R.B.,
DOI: 10.1016/bs.mcb.2015.06.013 SCOPUS: 84940676248.
Taylor S.P., Dantas T.J., Duran I., Wu S., Lachman R.S., Nelson S.F., Cohn D.H., Vallee R.B., Krakow D., Bamshad M.J., Shendure J., Nickerson D.A.,
DOI: 10.1038/ncomms8092 SCOPUS: 84935907084.
Daly O.M., Gaboriau D., Karakaya K., King S., Dantas T.J., Lalor P., Dockery P., Krämer A., Morrison C.G.,
DOI: 10.1242/jcs.186221 SCOPUS: 84968735321.
Conroy P.C., Saladino C., Dantas T.J., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.4161/cc.21986 SCOPUS: 84868020395.
Dantas T.J., Daly O.M., Conroy P.C., Tomas M., Wang Y., Lalor P., Dockery P., Ferrando-May E., Morrison C.G.,
DOI: 10.1371/journal.pone.0068487 SCOPUS: 84879770210.
Wang Y., Dantas T.J., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.4161/cc.23516 SCOPUS: 84874594469.
Dantas T.J., Wang Y., Lalor P., Dockery P., Morrison C.G.,
DOI: 10.1083/jcb.201012093 SCOPUS: 79955516456.
de Carvalho A.L.R.T., Strikoudis A., Liu H.Y., Chen Y.W., Dantas T.J., Vallee R.B., Correia-Pinto J., Snoeck H.W.,
DOI: 10.1242/dev.171652 SCOPUS: 85060395959.