The main topic of my research is the modulation of inflammation in tissue repair/regeneration, namely through the design of immunomodulatory microenvironments. At i3S I lead the Microenvironments for New Therapies (MiNT) group. MiNT bioengineers microenvironments that promote tissue regeneration/functional restoration through modulation of the host response.
My participation in research projects financially supported by a diversity of sources (e.g, European Commission), has fostered collaborations with China, USA, Brazil, France, Germany, Italy, Netherlands, Spain and Switzerland.
At the post-graduate level I have taken a leading role in launching undergraduate and post-doctoral programmes (e.g. the Doctoral Programme in Biomedical Engineering, in 1996, one of the first to operate in Portugal). Until 2020 I was the Director of the International Doctoral Programme on Molecular and Cellular Biotechnology Applied to Health Sciences (now in its 8th edition), that provides research training in bioengineering in top level institutions. I have been always strongly committed to provide advanced training in the area of biomaterials.
Among several awards is the George Winter Award of the European Society for Biomaterials (ESB), the ESB award for outstanding work of an established researcher, received in 2001. I am also the recipient of the Klaas de Groot 2020 Award, the ESB award for scientists who have shown a distinct ability to provide excellent mentorship and guidance to young researchers, helping them to establish their own independent career. I am a Fellow of the International Union of Societies for Biomaterials Science and Engineering. Since December 2020 I am the Secretary of the International Union of Societies for Biomaterials Science and Engineering (IUSBSE).
Former postdocs and students have leading positions in research institutes, both in Portugal and abroad (e.g. China, USA, Brazil and Spain). I was a founding member of Instituto de Engenharia Biomédica (INEB) set up in 1989, which is part of the i3S consortium.
Positions - From 2015 to December 2019, and following an application led by me, I was the Director of the I3S (Instituto de Investigação e Inovação em Saúde) of Porto University. I3S is the largest R&D research institute in Portugal, with >1300 investigators, 460 of them holding a PhD degree.. Until 2020 I was Full Professor at the Instituto de Ciências Biomédicas Abel Salazar (ICBAS) of the University of Porto. Since 2021 I am Emeritus Professor of University of Porto. I have taken leading positions in Portugal, namely as President (1992 to 1994) and Chairman of the Engineering Sciences Scientific Council (2002 to 2005) of the national agency for research (first JNICT and then FCT).
I have published more than 280 papers in refereed journals (Scopus data base), most of them in leading journals in biomaterials science. Associated to these are > 8800 citations and a h index of 52.
Web page: https://www.i3s.up.pt/research-group?x=32