Where Ideas grow
Susana Santos
Project Leader
Susana G. Santos (Orcid: http://orcid.org/0000-0002-8604-2978) is an Assistant Investigator at i3S-INEB. She did her basic degree in Biology and masters in Molecular Microbiology, at the University of Aveiro, before moving to the University of Porto to do her PhD as part of the G.A.B.B.A. program.She performed her PhD studies in the area of immunology, particularly Major Histocompatibility Complex in T cell biology, in a collaboration between ICBAS and IBMC at the University of Porto, Portugal and the College of Life Sciences at the University of Dundee, in Scotland, UK. After her PhD she worked on the biology of dendritic cells in the Medical School, at St Andrews University and later became a Medical Research Council (MRC) Career Development Fellow, at the MRC-Protein Phosphorylation Unit, at the College of Life Sciences in Dundee, studying different signalling pathways in the immune system. At the end of 2008 she moved back to Porto to work at INEB, as a Ciência 2007 fellow. She has been working on the relation between inflammation and tissue regeneration. Her current research interests are in modulating the immune and inflammatory responses to promote tissue repair/regeneration, and investigating the role of extracellular vesicles (including exosomes) in cell crosstalk during inflammation resolution and tissue regeneration.

Selected Publications

Silva A.M., Teixeira J.H., Almeida M.I., Gonçalves R.M., Barbosa M.A., Santos S.G.,
Extracellular Vesicles: Immunomodulatory messengers in the context of tissue repair/regeneration. European Journal of Pharmaceutical Sciences98:86-95, 2017. [Journal: Article] [CI: 46] [IF: 3,5]
DOI: 10.1016/j.ejps.2016.09.017 SCOPUS: 85000351063.


Cunha C., Almeida C.R., Almeida M.I., Silva A.M., Molinos M., Lamas S., Pereira C.L., Teixeira G.Q., Monteiro A.T., Santos S.G., Gonçalves R.M., Barbosa M.A.,
Systemic delivery of bone marrow mesenchymal stem cells for in situ intervertebral disc regeneration. Stem Cells Translational Medicine6(3):1029-1039, 2017. [Journal: Article] [CI: 17] [IF: 4,9]
DOI: 10.5966/sctm.2016-0033 SCOPUS: 85017568310.


Silva A.M., Almeida M.I., Teixeira J.H., Maia A.F., Calin G.A., Barbosa M.A., Santos S.G.,
Dendritic Cell-derived Extracellular Vesicles mediate Mesenchymal Stem/Stromal Cell recruitment. Scientific Reports7(1):, 2017. [Journal: Article] [CI: 27] [IF: 4,1]
DOI: 10.1038/s41598-017-01809-xh SCOPUS: 85019240385.


Oliveira M.I., Pinto M.L., Gonçalves R.M., Martins M.C.L., Santos S.G., Barbosa M.A.,
Adsorbed Fibrinogen stimulates TLR-4 on monocytes and induces BMP-2 expression. Acta Biomaterialia49:296-305, 2017. [Journal: Article] [CI: 15] [IF: 6,4]
DOI: 10.1016/j.actbio.2016.11.034 SCOPUS: 85007016045.


Vasconcelos D.M., Gonçalves R.M., Almeida C.R., Pereira I.O., Oliveira M.I., Neves N., Silva A.M., Ribeiro A.C., Cunha C., Almeida A.R., Ribeiro C.C., Gil A.M., Seebach E., Kynast K.L., Richter W., Lamghari M., Santos S.G., Barbosa M.A.,
Fibrinogen scaffolds with immunomodulatory properties promote inαvivo bone regeneration. Biomaterials111:163-178, 2016. [Journal: Article] [CI: 32] [IF: 8,4]
DOI: 10.1016/j.biomaterials.2016.10.004 SCOPUS: 84991771953.


Teixeira J.H., Silva A.M., Almeida M.I., Barbosa M.A., Santos S.G.,
Circulating extracellular vesicles: Their role in tissue repair and regeneration. Transfusion and Apheresis Science55(1):53-61, 2016. [Journal: Review] [CI: 17] [IF: 1,3]
DOI: 10.1016/j.transci.2016.07.015 SCOPUS: 84979696966.


Barbosa J.P., Neves A.R., Silva A.M., Barbosa M.A., Salette Reis M., Santos S.G.,
Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells. International Journal of Nanomedicine11:3501-3516, 2016. [Journal: Article] [CI: 20] [IF: 4,3]
DOI: 10.2147/IJN.S108694 SCOPUS: 84982733205.


Almeida M.I., Silva A.M., Vasconcelos D.M., Almeida C.R., Caires H., Pinto M.T., Calin G.A., Santos S.G., Barbosa M.A.,
miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis. Oncotarget7(1):7-22, 2016. [Journal: Article] [CI: 44] [IF: 5,2]
DOI: 10.18632/ONCOTARGET.6589 SCOPUS: 84969765513.


Teresa Pinto A., Laranjeiro Pinto M., Patrícia Cardoso A., Monteiro C., Teixeira Pinto M., Filipe Maia A., Castro P., Figueira R., Monteiro A., Marques M., Mareel M., Dos Santos S.G., Seruca R., Adolfo Barbosa M., Rocha S., JoséOliveira M.,
Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities. Scientific Reports6:, 2016. [Journal: Article] [CI: 65] [IF: 4,3]
DOI: 10.1038/srep18765 SCOPUS: 84954288518.


Vasconcelos D.M., Santos S.G., Lamghari M., Barbosa M.A.,
The two faces of metal ions: From implants rejection to tissue repair/regeneration. Biomaterials84:262-275, 2016. [Journal: Review] [CI: 52] [IF: 8,4]
DOI: 10.1016/j.biomaterials.2016.01.046 SCOPUS: 84979085747.