Where Ideas grow
Carla Cunha
Research Scientist

Carla Cunha is an Assistant Researcher at i3S. She obtained her PhD in Biology in 2007 by the Faculty of Sciences from the University of Porto, as a fellow of the GABBA PhD programme. Since then, she has been working on the area of Biomedical Engineering in Italy, USA and Australia. Research interests are centred on the combined used of stem cells and biomaterials for tissue engineering strategies in different target tissues. In particular, research has focused on nerve reconstruction, including development of in vitro 3D scaffolds made of functionalized self-assembling peptides for culture of neural stem cells and in vivo nerve regeneration strategies. Later on, osteochondral tissue engineering strategies were pursuit, with several novel biomaterials being tested in vitro and applied into osteochondral animal model defects. In 2012 she moved to Portugal to join INEB to focus in the intervertebral disc.

Selected Publications

Silva A.J., Ferreira J.R., Cunha C., Corte-Real J.V., Bessa-Gonçalves M., Barbosa M.A., Santos S.G., Gonçalves R.M.,
Macrophages down-regulate gene expression of intervertebral disc degenerative markers under a proinflammatory microenvironment. Frontiers in Immunology10(JUL):, 2019. [Journal: Article] [CI: 7] [IF: 5,1]
DOI: 10.3389/fimmu.2019.01508 SCOPUS: 85069037178.

Cunha C., Silva A.J., Pereira P., Vaz R., Gonçalves R.M., Barbosa M.A.,
The inflammatory response in the regression of lumbar disc herniation. Arthritis Research and Therapy20(1):, 2018. [Journal: Review] [CI: 18] [IF: 4,1]
DOI: 10.1186/s13075-018-1743-4 SCOPUS: 85056278077.

Silva A.M., Almeida M.I., Teixeira J.H., Ivan C., Oliveira J., Vasconcelos D., Neves N., Ribeiro-Machado C., Cunha C., Barbosa M.A., Calin G.A., Santos S.G.,
Profiling the circulating miRnome reveals a temporal regulation of the bone injury response. Theranostics8(14):3902-3917, 2018. [Journal: Article] [CI: 7] [IF: 8,1]
DOI: 10.7150/thno.24444 SCOPUS: 85049180465.

Cunha C., Almeida C.R., Almeida M.I., Silva A.M., Molinos M., Lamas S., Pereira C.L., Teixeira G.Q., Monteiro A.T., Santos S.G., Gonçalves R.M., Barbosa M.A.,
Systemic delivery of bone marrow mesenchymal stem cells for in situ intervertebral disc regeneration. Stem Cells Translational Medicine6(3):1029-1039, 2017. [Journal: Article] [CI: 17] [IF: 4,9]
DOI: 10.5966/sctm.2016-0033 SCOPUS: 85017568310.

Cunha C., Lamas S., Gonçalves R.M., Barbosa M.A.,
Joint analysis of IVD herniation and degeneration by rat caudal needle puncture model. Journal of Orthopaedic Research35(2):258-268, 2017. [Journal: Article] [CI: 13] [IF: 3,4]
DOI: 10.1002/jor.23114 SCOPUS: 85005992195.

Cunha C., Panseri S., Sandri M., Marcacci M., Tampieri A.,
Inspired by nature: Bio-inspired artificial scaffolds and the quest to replicate biology. Materials Today15(5):223, 2012. [Journal: Note] [CI: 4] [IF: 6,1]
DOI: 10.1016/S1369-7021(12)70098-6 SCOPUS: 84861656518.