Where Ideas Grow
Daniela Felício
PhD Student

Daniela Felício graduated in Biomedical Sciences at the University of Algarve (UAlg-FMCB) in 2019, with a final grade of 16/20. She performed a research project entitled "Ankylosing Spondylitis: Identification of polymorphisms in the HLA-B*27 allele and possible dietary susceptibility" at the BIOSKEL Group (CCMar, UAlg) under the supervision of Drs. Márcio Simão (CCMAR) and António Camacho (S. José Hospital, Lisbon), obtaining a classification of 19/20. The results of this projects were presented as poster communications at two meetings; with one original paper in preparation. Daniela completed her Master's degree in Molecular Genetics and Biomedicine at NOVA University Lisbon (UNL-FCT) in 2022, with a final grade of 18/20. Her master thesis entitled "Functional characterization of a novel TTBK2 variant in spinocerebellar ataxia type 11" was performed in the UnIGENe group at i3S-IBMC, under the supervision of Drs. Mariana Santos (i3S-IBMC) and Margarida Caldas Braga (UNL-FCT), receiving a classification of 19/20. This work was supported by a grant from Ataxia UK and focused on the cellular and molecular mechanisms underlying a novel missense variant in cerebellar ataxia using a CRISPR/Cas9 cell model. This work resulted in the publication of one abstract in conference proceedings (Eur J Hum Genet); two posters and one oral presentation; and one original paper in preparation. Currently, she is a Research Fellow (MSc) in Population Genetics and Evolution group (i3S-Ipatimup), working under the project 0702_MIGRAINEE_2_E - “Análisis y correlación entre la epigenética y la actividad cerebral para evaluar el riesgo de migraña crónica y episódica en mujeres” supported by the European Regional Development Fund (INTERREG V A España Portugal (POCTEP)). Her main role in this project is to evaluate non-coding variants effect on gene expression and migraine susceptibility.