Where Ideas Grow
Rui Freitas
PhD Student

Selected Publications

Freitas R., Peixoto A., Ferreira E., Miranda A., Santos L.L., Ferreira J.A.,
Immunomodulatory glycomedicine: Introducing next generation cancer glycovaccines. Biotechnology Advances65:, 2023. [Journal: Review] [CI: 4] [IF: 16 (*)]
DOI: 10.1016/j.biotechadv.2023.108144 SCOPUS: 85151687107.


Gaiteiro C., Soares J., Relvas-Santos M., Peixoto A., Ferreira D., Paulo P., Brandão A., Fernandes E., Azevedo R., Palmeira C., Freitas R., Miranda A., Osório H., Prieto J., Lima L., Silva A.M.N., Santos L.L., Ferreira J.A.,
Glycoproteogenomics characterizes the CD44 splicing code associated with bladder cancer invasion. Theranostics12(7):3150-3177, 2022. [Journal: Article] [CI: 9] [IF: 12,4]
DOI: 10.7150/thno.67409 SCOPUS: 85128304436.


Freitas R., Relvas-Santos M., Azevedo R., Soares J., Fernandes E., Teixeira B., Santos L.L., Silva A.M.N., Ferreira J.A.,
Single-pot enzymatic synthesis of cancer-associated MUC16: O -glycopeptide libraries and multivalent protein glycoconjugates: A step towards cancer glycovaccines. New Journal of Chemistry45(20):9197-9211, 2021. [Journal: Article] [CI: 5] [IF: 3,9]
DOI: 10.1039/d0nj06021f SCOPUS: 85106745147.


Peixoto A., Ferreira D., Azevedo R., Freitas R., Fernandes E., Relvas-Santos M., Gaiteiro C., Soares J., Cotton S., Teixeira B., Paulo P., Lima L., Palmeira C., Martins G., Oliveira M.J., Silva A.M.N., Santos L.L., Ferreira J.A.,
Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer. Journal of Experimental & Clinical Cancer Research40(1):, 2021. [Journal: Article] [CI: 12] [IF: 12,7]
DOI: 10.1186/s13046-021-01988-6 SCOPUS: 85107613140.


Fernandes E., Freitas R., Ferreira D., Soares J., Azevedo R., Gaiteiro C., Peixoto A., Oliveira S., Cotton S., Relvas-Santos M., Afonso L.P., Palmeira C., Oliveira M.J., Ferreira R., Silva A.M.N., Santos L.L., Ferreira J.A.,
Nucleolin-sle a glycoforms as E-selectin ligands and potentially targetable biomarkers at the cell surface of gastric cancer cells. Cancers12(4):, 2020. [Journal: Article] [CI: 18] [IF: 6,6]
DOI: 10.3390/cancers12040861 SCOPUS: 85083212499.


Fernandes E., Sores J., Cotton S., Peixoto A., Ferreira D., Freitas R., Reis C.A., Santos L.L., Ferreira J.A.,
Esophageal, gastric and colorectal cancers: Looking beyond classical serological biomarkers towards glycoproteomics-assisted precision oncology. Theranostics10(11):4903-4928, 2020. [Journal: Review] [CI: 36] [IF: 11,6]
DOI: 10.7150/thno.42480 SCOPUS: 85083755628.


Fernandes E., Ferreira D., Peixoto A., Freitas R., Relvas-Santos M., Palmeira C., Martins G., Barros A., Santos L.L., Sarmento B., Ferreira J.A.,
Glycoengineered nanoparticles enhance the delivery of 5-fluoroucil and paclitaxel to gastric cancer cells of high metastatic potential. International Journal of Pharmaceutics570:, 2019. [Journal: Article] [CI: 27] [IF: 4,8]
DOI: 10.1016/j.ijpharm.2019.118646 SCOPUS: 85071863114.