Researcher with a degree in Biology and a PhD in Veterinary Sciences on the effects of anaesthesia in rodents. As zebrafish research increased without the proper development of zebrafish welfare and husbandry, Ana started to study the effects of anaesthesia in zebrafish development and adulthood to refine the use of anaesthetic protocols. This line of research has been funded by leading two FCT projects (in collaboration with UTAD and CNC) and an individual post-doctoral fellowship. She has also been studying analgesia protocols in adult zebrafish, funded by the American College of Laboratory Animal Medicine (ACLAM). After being involved in a project to reduce zebrafish stress using fortified diets led by SPAROS, she currently has a CEEC contract (Scientific Employment Stimulus) to improve zebrafish analgesic protocols, which are still not used in many invasive procedures. In addition to the line of research on refinement of the laboratory animal anaesthesia and analgesia, the development of better euthanasia methods, husbandry conditions, and behaviour are also topics of interest. Trainer in Laboratory Animal Science courses, namely the advanced course at i3S. Board member of the Zebrafish Husbandry Association (ZHA, Int.) and member of the Association for the Study of Animal Behaviour ethical committee.
Selected Publications
Behavioural Aversion and Cortisol Level Assessment When Adult Zebrafish Are Exposed to Different Anaesthetics. Biology11(10):, 2022. [Journal: Article] [CI: 15] [IF: 4,2]
DOI: 10.3390/biology11101433 SCOPUS: 85140355980
Jorge S., Ferreira J.M., Olsson I.A.S., Valentim A.M.
Adult Zebrafish Anesthesia: A Study of Efficacy and Behavioral Recovery of Different Anesthetics. Zebrafish18(5):330-337, 2021. [Journal: Article] [CI: 20] [IF: 2,2]
DOI: 10.1089/zeb.2021.0023 SCOPUS: 85117356675
Félix L.M., Antunes L.M., Coimbra A.M., Valentim A.M.
Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology234(4):549-558, 2017. [Journal: Article] [CI: 53] [IF: 3,2]
DOI: 10.1007/s00213-016-4491-7 SCOPUS: 85001555685
Köhler A., Collymore C., Finger-Baier K., Geisler R., Kaufmann L., Pounder K.C., Schulte-Merker S., Valentim A., Varga Z.M., Weiss J., Strähle U.
Report of workshop on euthanasia for zebrafish - a matter of welfare and science. Zebrafish14(6):547-551, 2017. [Journal: Article] [CI: 35] [IF: 1,7]
DOI: 10.1089/zeb.2017.1508 SCOPUS: 85036516157
Valentim A.M., Félix L.M., Carvalho L., Diniz E., Antunes L.M.
A new anaesthetic protocol for adult zebrafish (Danio rerio): Propofol combined with lidocaine. PLoS ONE11(1):, 2016. [Journal: Article] [CI: 64] [IF: 2,8]
DOI: 10.1371/journal.pone.0147747 SCOPUS: 84959205162
Valentim A.M., van Eeden F.J., Strähle U., Olsson I.A.S.
Euthanizing zebrafish legally in Europe: Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?. EMBO Reports17(12):1688-1689, 2016. [Journal: Note] [CI: 32] [IF: 8,6]
DOI: 10.15252/embr.201643153 SCOPUS: 84995451033
Martins T., Valentim A.M., Pereira N., Antunes L.M.
Anaesthesia and analgesia in laboratory adult zebrafish: A question of refinement. Laboratory Animals50(6):476-488, 2016. [Journal: Article] [CI: 61] [IF: 1,5]
DOI: 10.1177/0023677216670686 SCOPUS: 85014491998
Félix L., Correia R., Sequeira R., Ribeiro C., Monteiro S., Antunes L., Silva J., Venâncio C., Valentim A.
Ms-222 and propofol sedation during and after the simulated transport of nile tilapia (Oreochromis niloticus). Biology10(12):, 2021. [Journal: Article] [CI: 22] [IF: 5,2]
DOI: 10.3390/biology10121309 SCOPUS: 85121573998
Guedes S.R., Valentim A.M., Antunes L.M.
Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task. Applied Animal Behaviour Science189:91-97, 2017. [Journal: Article] [CI: 17] [IF: 1,5]
DOI: 10.1016/j.applanim.2017.01.012 SCOPUS: 85011556791
Valentim A.M., Di Giminiani P., Ribeiro P.O., Rodrigues P., Olsson I.A.S., Antunes L.M.
Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations. Anesthesiology113(5):1099-1108, 2010. [Journal: Article] [CI: 45] [IF: 5,5]
DOI: 10.1097/ALN.0b013e3181f79c7c SCOPUS: 78049352411
