Where Ideas Grow
Joana Silva
Junior Researcher

Joana Silva is a Junior Researcher in the Molecular Biomaterials Group at i3S. Her research work focuses on the development of supramolecular hydrogels combining peptides and natural polymers for different applications, for instance, cell culture, in vitro 3D models and regenerative medicine.

Joana graduated from the Faculty of Engineering of the University of Porto (FEUP) with a Master's degree in BioEngineering – Biomedical Engineering (2012). Her Master's thesis was entitled “Evaluation of different synthetic ligands ability to promote cell migration of ES-derived neural stem cells: a step forward to the development of molecularly-designed hydrogels for neural stem cell transplantation”. After finishing her studies, she joined the Institute of Biomedical Engineering in Porto (INEB) as a Research Assistant working on the design of fibrin hydrogels in the framework of spinal cord injury. In 2021, she earned her Ph.D. in Organic Chemistry from the University of Manchester (UK). Her thesis was entitled “Combining synthesis and industrial biotechnology for high-throughput biomaterials functionalization”.

With an interdisciplinary background, Joana’s areas of expertise include hydrogel biomaterials, drug delivery, cell culture, organic chemistry, and characterization and functionalization of biomaterials. 

Selected Publications

Silva J., Azevedo H.S.,
Bioengineered Hyaluronan Hydrogels for the Delivery of Molecular and Cellular Therapies. Advanced Therapeutics7(1):, 2024. [Journal: Review] [IF: 4,6 (*)]
DOI: 10.1002/adtp.202300182 SCOPUS: 85172304979.


Silva J., Spiess R., Marchesi A., Flitsch S.L., Gough J.E., Webb S.J.,
Enzymatic elaboration of oxime-linked glycoconjugates in solution and on liposomes. Journal of Materials Chemistry B10(26):5016-5027, 2022. [Journal: Article] [IF: 7]
DOI: 10.1039/d2tb00714b SCOPUS: 85132783925.


Fallows T.W., McGrath A.J., Silva J., McAdams S.G., Marchesi A., Tuna F., Flitsch S.L., Tilley R.D., Webb S.J.,
High-throughput chemical and chemoenzymatic approaches to saccharide-coated magnetic nanoparticles for MRI. Nanoscale Advances1(9):3597-3606, 2019. [Journal: Article] [CI: 5]
DOI: 10.1039/c9na00376b SCOPUS: 85072200908.


Craven F.L., Silva J., Segarra-Maset M.D., Huang K., Both P., Gough J.E., Flitsch S.L., Webb S.J.,
'One-pot' sequential enzymatic modification of synthetic glycolipids in vesicle membranes. Chemical Communications54(11):1347-1350, 2018. [Journal: Article] [CI: 11] [IF: 6,2]
DOI: 10.1039/c7cc09148f SCOPUS: 85041411055.


Silva J., Bento A.R., Barros D., Laundos T.L., Sousa S.R., Quelhas P., Sousa M.M., Pêgo A.P., Amaral I.F.,
Fibrin functionalization with synthetic adhesive ligands interacting with a6ß1 integrin receptor enhance neurite outgrowth of embryonic stem cell-derived neural stem/progenitors. Acta Biomaterialia59:243-256, 2017. [Journal: Article] [CI: 16] [IF: 6,4]
DOI: 10.1016/j.actbio.2017.07.013 SCOPUS: 85023776762.


Laundos T.L., Silva J., Assunção M., Quelhas P., Monteiro C., Oliveira C., Oliveira M.J., Pêgo A.P., Amaral I.F.,
Rotary orbital suspension culture of embryonic stem cell-derived neural stem/progenitor cells: impact of hydrodynamic culture on aggregate yield, morphology and cell phenotype. Journal of Tissue Engineering and Regenerative Medicine11(8):2227-2240, 2017. [Journal: Article] [CI: 5] [IF: 4,1]
DOI: 10.1002/term.2121 SCOPUS: 84975769766.