Where Ideas Grow
Filipa Ferreira
Animal Welfare and Ethics Review Body
Team Member

I finished my degree in Anatomical Pathology in 2006. In 2008, I started my Master in Molecular Therapies where I studied the role of Transthyretin (TTR) in the peripheral nerve and bone biology in the Nerve Regeneration Group. In 2010, I started my PhD in Biomedical Sciences where the main goal was to characterize genes with unknown function highly expressed in the spinal cord and the dorsal root ganglion. Since 2016, I integrated the Animal Facility to engage the developement of mouse models by CRISPR-Cas9, cryopreservation of mouse embryos and other services provided by the facility.

Selected Publications

Fleming C.E., Mar F.M., Franquinho F., Saraiva M.J., Sousa M.M.,
Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity. Journal of Neuroscience29(10):3220-3232, 2009. [Journal: Article] [CI: 86] [IF: 7,2]
DOI: 10.1523/JNEUROSCI.6012-08.2009 SCOPUS: 63849199799.


Mar F.M., Franquinho F., Fleming C.E., Sousa M.M.,
Transthyretin in peripheral nerve regeneration. Future Neurology4(6):723-730, 2009. [Journal: Review] [CI: 3]
DOI: 10.2217/fnl.09.50 SCOPUS: 75249088053.


Franquinho F., Nogueira-Rodrigues J., Duarte J.M., Esteves S.S., Carter-Su C., Monaco A.P., Molnár Z., Velayos-Baeza A., Brites P., Sousa M.M.,
The dyslexia-susceptibility protein kiaa0319 inhibits axon growth through smad2 signaling. Cerebral cortex (New York, N.Y. : 1991)27(3):1732-1747, 2017. [Journal: Article] [CI: 22] [IF: 6,3]
DOI: 10.1093/cercor/bhx023 SCOPUS: 85021858395.


Miranda C.O., Teixeira C.A., Liz M.A., Sousa V.F., Franquinho F., Forte G., Di Nardo P., Pinto-Do-Ó P., Sousa M.M.,
Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease. Stem Cells29(11):1738-1751, 2011. [Journal: Article] [CI: 23] [IF: 7,8]
DOI: 10.1002/stem.724 SCOPUS: 80054957115.


Nunes A.F., Liz M.A., Franquinho F., Teixeira L., Sousa V., Chenu C., Lamghari M., Sousa M.M.,
Neuropeptide y expression and function during osteoblast differentiation - Insights from transthyretin knockout mice. FEBS Journal277(1):263-275, 2010. [Journal: Article] [CI: 34] [IF: 3,1]
DOI: 10.1111/j.1742-4658.2009.07482.x SCOPUS: 73649127668.


Liz M.A., Mar F.M., Franquinho F., Sousa M.M.,
Aboard transthyretin: From transport to cleavage. IUBMB Life62(6):429-435, 2010. [Journal: Review] [CI: 50] [IF: 4,3]
DOI: 10.1002/iub.340 SCOPUS: 77953605034.


Franquinho F., Liz M.A., Nunes A.F., Neto E., Lamghari M., Sousa M.M.,
Neuropeptide y and osteoblast differentiation - The balance between the neuro-osteogenic network and local control: Review Article. FEBS Journal277(18):3664-3674, 2010. [Journal: Review] [CI: 47] [IF: 3,1]
DOI: 10.1111/j.1742-4658.2010.07774.x SCOPUS: 77956337408.


Nunes A.F., Montero M., Franquinho F., Santos S.D., Malva J., Zimmer J., Sousa M.M.,
Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration. Neurochemistry International55(7):454-457, 2009. [Journal: Article] [CI: 7] [IF: 3,5]
DOI: 10.1016/j.neuint.2009.07.001 SCOPUS: 69349100059.


Fleming C.E., Mar F.M., Franquinho F., Sousa M.M.,
Chapter 17 Transthyretin. An Enhancer of Nerve Regeneration. International Review of Neurobiology87(C):337-346, 2009. [Book Series: Review] [CI: 15] [IF: 4]
DOI: 10.1016/S0074-7742(09)87017-7 SCOPUS: 70349784345.