I finished my degree in Anatomical Pathology in 2006. In 2008, I started my Master in Molecular Therapies where I studied the role of Transthyretin (TTR) in the peripheral nerve and bone biology in the Nerve Regeneration Group. In 2010, I started my PhD in Biomedical Sciences where the main goal was to characterize genes with unknown function highly expressed in the spinal cord and the dorsal root ganglion. Since 2016, I integrated the Animal Facility to engage the developement of mouse models by CRISPR-Cas9, cryopreservation of mouse embryos and other services provided by the facility.
Selected Publications
Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity. Journal of Neuroscience29(10):3220-3232, 2009. [Journal: Article] [CI: 95] [IF: 7,2]
DOI: 10.1523/JNEUROSCI.6012-08.2009 SCOPUS: 63849199799
Mar F.M., Franquinho F., Fleming C.E., Sousa M.M.
Transthyretin in peripheral nerve regeneration. Future Neurology4(6):723-730, 2009. [Journal: Review] [CI: 4]
DOI: 10.2217/fnl.09.50 SCOPUS: 75249088053
Franquinho F., Nogueira-Rodrigues J., Duarte J.M., Esteves S.S., Carter-Su C., Monaco A.P., Molnár Z., Velayos-Baeza A., Brites P., Sousa M.M.
The dyslexia-susceptibility protein kiaa0319 inhibits axon growth through smad2 signaling. Cerebral cortex (New York, N.Y. : 1991)27(3):1732-1747, 2017. [Journal: Article] [CI: 29] [IF: 6,3]
DOI: 10.1093/cercor/bhx023 SCOPUS: 85021858395
Miranda C.O., Teixeira C.A., Liz M.A., Sousa V.F., Franquinho F., Forte G., Di Nardo P., Pinto-Do-Ó P., Sousa M.M.
Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease. Stem Cells29(11):1738-1751, 2011. [Journal: Article] [CI: 24] [IF: 7,8]
DOI: 10.1002/stem.724 SCOPUS: 80054957115
Nunes A.F., Liz M.A., Franquinho F., Teixeira L., Sousa V., Chenu C., Lamghari M., Sousa M.M.
Neuropeptide y expression and function during osteoblast differentiation - Insights from transthyretin knockout mice. FEBS Journal277(1):263-275, 2010. [Journal: Article] [CI: 39] [IF: 3,1]
DOI: 10.1111/j.1742-4658.2009.07482.x SCOPUS: 73649127668
Liz M.A., Mar F.M., Franquinho F., Sousa M.M.
Aboard transthyretin: From transport to cleavage. IUBMB Life62(6):429-435, 2010. [Journal: Review] [CI: 56] [IF: 4,3]
DOI: 10.1002/iub.340 SCOPUS: 77953605034
Franquinho F., Liz M.A., Nunes A.F., Neto E., Lamghari M., Sousa M.M.
Neuropeptide y and osteoblast differentiation - The balance between the neuro-osteogenic network and local control: Review Article. FEBS Journal277(18):3664-3674, 2010. [Journal: Review] [CI: 52] [IF: 3,1]
DOI: 10.1111/j.1742-4658.2010.07774.x SCOPUS: 77956337408
Nunes A.F., Montero M., Franquinho F., Santos S.D., Malva J., Zimmer J., Sousa M.M.
Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration. Neurochemistry International55(7):454-457, 2009. [Journal: Article] [CI: 8] [IF: 3,5]
DOI: 10.1016/j.neuint.2009.07.001 SCOPUS: 69349100059
Fleming C., Mar F., Franquinho F., Sousa M.
Chapter 17 Transthyretin. An Enhancer of Nerve Regeneration. International Review of Neurobiology87(C):337-346, 2009. [Book Series: Review] [CI: 16] [IF: 4]
DOI: 10.1016/S0074-7742(09)87017-7 SCOPUS: 70349784345
