José C. Machado (JCM) is Full Professor in the Faculty of Medicine of Porto, member of the Boards of i3S and Ipatimup, and Group Leader at i3S. He studied Biology at the University of Porto and developed his PhD in the Universities of Tubingen, Germany and Porto, Portugal. The scientific goal that drives JCM's research group is to understand the biological significance of communication among cells of the tumor microenvironment, and determine how it influences cancer onset, progression, and clinical response. JCM is also the head of the molecular genetics laboratory of the IPATIMUP Diagnostics Unit. This is one of the reference laboratories in Portugal for the detection of cancer biomarkers and genetic diagnosis of hereditary cancer syndromes. As of July 2023, JCM co-authors 188 publications, with 14465 total citations, and with an h-index of 48 (Scopus Author ID 7102792651).