Where Ideas Grow

Course in Experimental Design and Analysis of Data for Research with Animals

4-6 December 2019 | i3S, Porto


This course aims at making researchers sufficiently knowledgeable on experimental design and statistics to make results from animal experiments more reliable, robust and reproducible, while avoiding animal waste and complying with the 3Rs of animal research, with particular emphasis on Reduction and Refinement.
This course is particularly aimed at researchers responsible for designing and/or carrying out animal experiments.

Organization: Nuno Franco, i3S



  • Planning for reproducibility in animal research
  • The 3Rs in an experimental programme
  • Formulating objectives and testing hypotheses
  • Basic design considerations and types of design
  • Avoidance of bias (randomization, blind assessment, adequate controls)
  • Independent replication and experimental units
  • Estimating sample size
  • Basic concepts in probability and statistics
  • Single and two factor analysis of variance
  • Analysis of covariance
  • Data transformations and non-parametric methods
  • Multivariate analysis of variance



Derek Fry, The University of Manchester

Dr Fry was Chief Inspector of the UK Animal Scientific Procedures Inspectorate, until his retirement in 2008 and is now a consultant on animal experimentation issues and experimental design, with an honorary post at the University of Manchester.  In the UK Inspectorate he assessed animal experimentation proposals and advised government on ethical issues for nearly 20 years.  Since retiring he has concentrated on his interest in experimental design and helped develop the FRAME experimental design courses.  He has now run or contributed to workshops on experimental design and project assessment in UK and various countries in Europe, Asia and North America.


Pedro Oliveira, ICBAS

Pedro Oliveira graduated in Chemical Engineering in 1984. In 1992, he concluded a PhD in Applied Mathematics at Strathclyde University, Glasgow. He was Professor at the University of Minho till 2010. Since 2010, he is Associate Professor (Biostatistics and Numerical methods) at the Biomedical Sciences Institute Abel Salazar and at the Institute of Public Health from the University of Porto. He is member of the Epidemiological Research Unit, EPIUnit, where he coordinates the Biostatistics and Health Metrics group. His main research interests are in Biostatistics, in particular, in the application and development statistical methods in public health, planning and data analysis.



Registration fee includes coffee breaks and course materials. Lunches are not included in the registration fees.



Limited number of participants: 20 (10 for i3S members)



Your registration will be confirmed and the payment will be requested once the minimum of participants is guaranteed. The payment has to be done until 10 working days after the registration confirmation.


More Information:
Advanced Training Unit | E-mail: training@i3s.up.pt | Tel: +351 220 408 800