Pedro Martins
Biomolecular Structure & Function
Junior Researcher
PhD by University of Porfo (2009) and i3S Principal Investigator with over 15 years of interdisciplinary experience bridging fundamental biophysics, mathematical modeling, and pharmaceutical innovation in the field of nerodegenerative diseasaes. Research focuses on translating academic discoveries into therapeutic applications, particularly in Alzheimer's disease, Parkinson's disease and spinocerebellar ataxias. Experienced in securing competitive research funding, developing patented formulations, and fostering industry-academia partnerships.
Selected Publications
Silva A., Almeida B., Fraga J.S., Taboada P., Martins P.M., Macedo-Ribeiro S.
Distribution of Amyloid-Like and Oligomeric Species from Protein Aggregation Kinetics. Angewandte Chemie - International Edition56(45):14042-14045, 2017. [Journal: Article] [CI: 17] [IF: 12,1]
DOI: 10.1002/anie.201707345 SCOPUS: 85032264546
Crespo R., Villar-Alvarez E., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
What can the kinetics of amyloid fibril formation tell about off-pathway aggregation?. Journal of Biological Chemistry291(4):2018-2032, 2016. [Journal: Article] [CI: 44] [IF: 4,1]
DOI: 10.1074/jbc.M115.699348 SCOPUS: 84959017740
Pinto M.F., Estevinho B.N., Crespo R., Rocha F.A., Damas A.M., Martins P.M.
Enzyme kinetics: The whole picture reveals hidden meanings. FEBS Journal282(12):2309-2316, 2015. [Journal: Article] [CI: 12] [IF: 4,2]
DOI: 10.1111/febs.13275 SCOPUS: 84935876997
Silva A., Sárkány Z., Fraga J.S., Taboada P., Macedo-Ribeiro S., Martins P.M.
Probing the occurrence of soluble oligomers through amyloid aggregation scaling laws. Biomolecules8(4):, 2018. [Journal: Article] [CI: 11] [IF: 4,7]
DOI: 10.3390/biom8040108 SCOPUS: 85054461653
Sárkány Z., Rocha F., Damas A., Macedo-Ribeiro S., Martins P.
Chemical Kinetic Strategies for High-Throughput Screening of Protein Aggregation Modulators. Chemistry - An Asian Journal14(4):500-508, 2019. [Journal: Review] [CI: 10] [IF: 4,1]
DOI: 10.1002/asia.201801703 SCOPUS: 85060928161
Pinto M.F., Ripoll-Rozada J., Ramos H., Watson E.E., Franck C., Payne R.J., Saraiva L., Pereira P.J.B., Pastore A., Rocha F., Martins P.M.
A simple linearization method unveils hidden enzymatic assay interferences. Biophysical Chemistry252:, 2019. [Journal: Article] [CI: 7] [IF: 2]
DOI: 10.1016/j.bpc.2019.106193 SCOPUS: 85066943005
Crespo R., Villar-Alvarez E., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
Insoluble Off-Pathway Aggregates as Crowding Agents during Amyloid Fibril Formation. Journal of Physical Chemistry B121(10):2288-2298, 2017. [Journal: Article] [CI: 11] [IF: 3,1]
DOI: 10.1021/acs.jpcb.7b01120 SCOPUS: 85018260883
Ferreira C., Rocha F.A., Damas A.M., Martins P.M.
The Finding of Nondissolving Lysozyme Crystals and Its Significance for the Study of Hard-to-Crystallize Biological Macromolecules. Crystal Growth and Design16(8):4285-4291, 2016. [Journal: Article] [CI: 4] [IF: 4,1]
DOI: 10.1021/acs.cgd.6b00334 SCOPUS: 84982727296
Ferreira C., Barbos S., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
The nucleation of protein crystals as a race against time with on- and off-pathways. Journal of Applied Crystallography50:1056-1065, 2017. [Journal: Article] [CI: 9] [IF: 3,4]
DOI: 10.1107/S1600576717007312 SCOPUS: 85027011873
Watson E.E., Ripoll-Rozada J., Lee A.C., Wu M.C.L., Franck C., Pasch T., Premdjee B., Sayers J., Pinto M.F., Martins P.M., Jackson S.P., Pereira P.J.B., Payne R.J.
Rapid assembly and profiling of an anticoagulant sulfoprotein library. Proceedings of the National Academy of Sciences of the United States of America116(28):13873-13878, 2019. [Journal: Article] [CI: 26] [IF: 9,4]
DOI: 10.1073/pnas.1905177116 SCOPUS: 85066962891
Distribution of Amyloid-Like and Oligomeric Species from Protein Aggregation Kinetics. Angewandte Chemie - International Edition56(45):14042-14045, 2017. [Journal: Article] [CI: 17] [IF: 12,1]
DOI: 10.1002/anie.201707345 SCOPUS: 85032264546
Crespo R., Villar-Alvarez E., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
What can the kinetics of amyloid fibril formation tell about off-pathway aggregation?. Journal of Biological Chemistry291(4):2018-2032, 2016. [Journal: Article] [CI: 44] [IF: 4,1]
DOI: 10.1074/jbc.M115.699348 SCOPUS: 84959017740
Pinto M.F., Estevinho B.N., Crespo R., Rocha F.A., Damas A.M., Martins P.M.
Enzyme kinetics: The whole picture reveals hidden meanings. FEBS Journal282(12):2309-2316, 2015. [Journal: Article] [CI: 12] [IF: 4,2]
DOI: 10.1111/febs.13275 SCOPUS: 84935876997
Silva A., Sárkány Z., Fraga J.S., Taboada P., Macedo-Ribeiro S., Martins P.M.
Probing the occurrence of soluble oligomers through amyloid aggregation scaling laws. Biomolecules8(4):, 2018. [Journal: Article] [CI: 11] [IF: 4,7]
DOI: 10.3390/biom8040108 SCOPUS: 85054461653
Sárkány Z., Rocha F., Damas A., Macedo-Ribeiro S., Martins P.
Chemical Kinetic Strategies for High-Throughput Screening of Protein Aggregation Modulators. Chemistry - An Asian Journal14(4):500-508, 2019. [Journal: Review] [CI: 10] [IF: 4,1]
DOI: 10.1002/asia.201801703 SCOPUS: 85060928161
Pinto M.F., Ripoll-Rozada J., Ramos H., Watson E.E., Franck C., Payne R.J., Saraiva L., Pereira P.J.B., Pastore A., Rocha F., Martins P.M.
A simple linearization method unveils hidden enzymatic assay interferences. Biophysical Chemistry252:, 2019. [Journal: Article] [CI: 7] [IF: 2]
DOI: 10.1016/j.bpc.2019.106193 SCOPUS: 85066943005
Crespo R., Villar-Alvarez E., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
Insoluble Off-Pathway Aggregates as Crowding Agents during Amyloid Fibril Formation. Journal of Physical Chemistry B121(10):2288-2298, 2017. [Journal: Article] [CI: 11] [IF: 3,1]
DOI: 10.1021/acs.jpcb.7b01120 SCOPUS: 85018260883
Ferreira C., Rocha F.A., Damas A.M., Martins P.M.
The Finding of Nondissolving Lysozyme Crystals and Its Significance for the Study of Hard-to-Crystallize Biological Macromolecules. Crystal Growth and Design16(8):4285-4291, 2016. [Journal: Article] [CI: 4] [IF: 4,1]
DOI: 10.1021/acs.cgd.6b00334 SCOPUS: 84982727296
Ferreira C., Barbos S., Taboada P., Rocha F.A., Damas A.M., Martins P.M.
The nucleation of protein crystals as a race against time with on- and off-pathways. Journal of Applied Crystallography50:1056-1065, 2017. [Journal: Article] [CI: 9] [IF: 3,4]
DOI: 10.1107/S1600576717007312 SCOPUS: 85027011873
Watson E.E., Ripoll-Rozada J., Lee A.C., Wu M.C.L., Franck C., Pasch T., Premdjee B., Sayers J., Pinto M.F., Martins P.M., Jackson S.P., Pereira P.J.B., Payne R.J.
Rapid assembly and profiling of an anticoagulant sulfoprotein library. Proceedings of the National Academy of Sciences of the United States of America116(28):13873-13878, 2019. [Journal: Article] [CI: 26] [IF: 9,4]
DOI: 10.1073/pnas.1905177116 SCOPUS: 85066962891
