Where Ideas Grow
Hugo Santos Sousa
Glycobiology in Cancer
Clinical Affiliate Member

EDUCATION

2004: MD, Faculty of Medicine University of Porto (FMUP)

2010: MSc in Molecular Medicine and Oncology (Thesis: Current view of gastric carcinoma: from the need for early diagnosis to the identification of biomarkers based on changes in the glycosylation of proteins), FMUP/IPATIMUP

2017: FACS, Fellow of American College of Surgeons

2018: Harvard Alumni, Harvard Medical School 2016-2018 Portugal Clinical Scholars Research Training (PTCSRT)

Present: PhD Student in Molecular Medicine and Oncology, FMUP

POST-GRADUATE EDUCATION

2006 - 2012: General Surgery Residency, Department of Surgery, Centro Hospitalar de São João [Head of Department: Dr. José Costa-Maia MD FACS FEBS]

2011: Visiting Resident (Hands-on) in Thoracic and Upper GI Surgical Oncology, Klinikum Nürnberg Nord, Nürnberg, Germany [Head of Department: Prof. Hubert Stein MD FACS]

2011: Visiting Resident (Observership) in Upper GI Surgical Oncology, UPMC Presbyterian, Pittsburgh, USA [Head of Department: Dr. James Luketich MD FACS]

2011: Visiting Resident (Observership) in Laparoscopic Digestive and Obesity Surgery, Les Hôpitaux Universitaires de Strasbourg - IRCAD/EITS, Strasbourg, France [Head of Department: Prof. Jacques Marescaux MD FRCS FACS]

2012: Visiting Fellow (Observership) in Minimally Invasive Colorectal Surgery and Oncology, St Marks Hospital & Academic Institute, London, UK [Head of Department: Prof. Robin Phillips MB BS MS FRCS]

2012: Visiting Fellow (Hands-on) in Upper GI Surgical Oncology, Queen Mary Hospital, Hong Kong [Chief of Division: Prof. Simon Law MBBChir (Cantab), MS (HK), FRCS (Edin), FCSHK, FHKAM (Surgery)]

2012: Visiting Fellow (Observership) in HPB Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA [Chief of Service: Prof. Jean- Nicolas Vauthey MD FACS]

2017: Visiting Fellow (Observership) in Minimally Invasive Gastric Cancer Surgery; Visiting Program in Chinese Institutions (VPCI) Award - 12th International Gastric Cancer Congress (IGCC 2017), Peking University Cancer Hospital, Beijing, China [Head of Department: Prof. Jiafu Ji MD FACS]

CURRENT CLINICAL ACTIVITY

2013 - Present: Attending in Upper GI and Bariatric Surgery, Division of Upper GI Surgery & Center of Excellence - Obesity, Department of Surgery, Centro Hospitalar de São João [Head of Department: Dr. José Costa- Maia MD FACS FEBS]

2017 - Present: General Surgeon, Private Practice, Obesity Clinics and Department of Surgery, Casa de Saúde da Boavista

ACADEMIC ACTIVITY

2006 - Present: Professor (Invited Assistant), Surgery 4th Year, Integrated Master in Medicine, Faculty of Medicine University of Porto (FMUP)

2009 - 2016: Monitor (Invited), Surgical Gestures Indispensable in Clinical Practice (6th Year), Integrated Master in Medicine, FMUP

SCIENTIFIC ACTIVITY

7 Papers (2 as First Author) and 104 Abstracts (41 as First Author) published in Peer-Reviewed Journals

14 Invited Lectures in International and National Conferences & Meetings

300 Papers presented in International and National Conferences & Meetings

7 Supervisions and 3 Co-supervisions of Integrated Master Thesis in Medicine (FMUP)

MEMBERSHIP OF SCIENTIFIC SOCIETIES

Research on Oncology: European Association for Cancer Research (EACR, 2012), Portuguese Association for Cancer Research (ASPIC, 2013), American Association for Cancer Research (AACR, 2013)

Surgical Oncology: American Society of Clinical Oncology (ASCO, 2011), European Society for Medical Oncology (ESMO, 2011), European Society of Surgical Oncology (ESSO, 2011), Society of Surgical Oncology (SSO, 2012), Portuguese Society of Oncology (SPO, 2013)

Upper GI: International Society for Diseases of the Esophagus (ISDE, 2012), Society for Surgery of the Alimentary Tract (SSAT, 2012), International Gastric Cancer Association (IGCA, 2012), European Society of Digestive Oncology (ESDO, 2015), Research Group for Digestive Cancer (GICD, 2015)

General Surgery: American College of Surgeons (ACS, 2009), Portuguese Society of Surgery (SPC, 2013)

LIST OF PUBLICATIONS IN PEER-REVIEWED INDEXED JOURNALS

  1. Schweigert M, Santos Sousa H, Solymosi N, Yankulov A, Fernández MJ, Beattie R, Dubecz A, Rabl C, Law S, Tong D, Petrov D, Schäbitz A, Stadlhuber RJ, Gumpp J, Ofner
D, McGuigan J, Costa-Maia J, Witzigmann H, Stein HJ, Spotlight on esophageal perforation – A multinational study using the Pittsburgh esophageal perforation severity scoring system, The Journal of Thoracic and Cardiovascular Surgery (2016), Article in press

  2. Santos-Sousa H, Bouça-Machado T, Dubecz A, Barbosa E, Costa-Maia J, O que pensam os Internos de Cirurgia Geral do seu Internato?, Revista Portuguesa de Cirurgia 2015; 35: 13-21

  3. J. Barbosa, S. Carneiro, J. Preto, H. Sousa, A. Pinho, C. Maia, Laparoscopic Gastrectomy after the Age of Eighty: Still a Good Choice?, Journal of Cancer Therapy, 2013 Oct; 4(9A), 2013: 27- 30

  4. Faria GR, Pinto-de-Sousa J, Preto JR, Sousa HS, Barbosa JA, Costa-Maia J., Three decades of clinical-pathological trends in Gastric Cancer: prospective data from a Portuguese Hospital, Int J Surg. 2013 Apr 18; 11(6): 472-6

  5. Gomes C, Almeida A, Ferreira JA, Silva L, Santos-Sousa H, Pinto-de-Sousa J, Santos LL, Amado F, Schwientek T, Levery SB, Mandel U, Clausen H, David L, Reis CA, Osório H, Glycoproteomic Analysis of Serum from Patients with Gastric Precancerous Lesions, J Proteome Res. 2013 Mar 1; 12(3): 1454-66

  6. Leite S, Taveira-Gomes A, Sousa H, Visceral injury in abdominal trauma: a retrospective study, Acta Med Port. 2013 Nov-Dec; 26(6): 725-30.

  7. Santos-Sousa H, Bouça-Machado T, Pinto-de-Sousa J, Preto J, Lima-da-Costa E, Costa-Maia J, Early onset gastric cancer: uma entidade clínica distinta com um prognóstico diferente?, Revista Portuguesa de Cirurgia 2012; 20: 21-30

LIST OF MOST RELEVANT ABSTRACTS PUBLISHED IN PEER-REVIEWED INDEXED JOURNALS

  1. Annals of Oncology (2017), 28(S3): Abstr 70, Is lymph node ratio in surgical treatment of esophageal squamous cell carcinoma better than classic TNM system?, Devezas, Vítor; Santos-Sousa, Hugo; Caldeira, Beatriz; Torres, Mónica; Mesquita, Márcio; Aral, Marisa; Barbosa, José; Costa-Maia, José

  2. Annals of Oncology (2017), 28(S3): Abstr 129, The effect of perioperative blood transfusions in recurrence and survival following gastric cancer surgery, Caldeira, Beatriz; Santos-Sousa, Hugo; Fernandes, Mariana; Castro, Bárbara; Devezas, Vítor; Torres, Mónica; Fareleira, Ana; Aral, Marisa; Barbosa, José; Costa-Maia, José

  3. Annals of Oncology (2017), 28(S3): Abstr 130, Impact of the number of lymph nodes harvested in gastric cancer patients prognosis, Fernandes, Mariana; Santos-Sousa, Hugo; Caldeira, Beatriz; Torres, Mónica; Aral, Marisa; Fareleira, Ana; Devezas, Vítor; Castro, Bárbara; Barbosa, José; Costa-Maia, José

  4. Annals of Oncology (2017), 28(S3): Abstr 131, Prognostic factors for node-negative advanced gastric cancer after curative gastrectomy, Caldeira, Beatriz; Santos-Sousa, Hugo; Fernandes, Mariana; Castro, Bárbara; Devezas, Vítor; Torres, Mónica; Fareleira, Ana; Aral, Marisa; Barbosa, José; Costa-Maia, José

  5. Annals of Oncology (2017), 28(S3): Abstr 132, Outcomes of gastric cancer surgery in elderly patients, Caldeira, Beatriz; Santos-Sousa, Hugo; Fernandes, Mariana; Castro, Bárbara; Devezas, Vítor; Torres, Mónica; Fareleira, Ana; Aral, Marisa; Barbosa, José; Costa-Maia, José

  6. Annals of Oncology (2016), 27(S2): Abstr 260, Outcomes of laparoscopic and open gastrectomy for gastric cancer: a comparative analysis, B. Castro, M. Aral, A. Fareleira, J. Costa-Maia, H. Santos-Sousa

  7. Annals of Oncology (2016), 27(S2): Abstr 263, Laparoscopic versus open distal gastrectomy for gastric cancer: a single-center case-control study, B. Castro, M. Aral, A. Fareleira, J. Costa-Maia, H. Santos-Sousa

  8. Annals of Oncology (2016), 27(S2): Abstr 264, Is laparoscopic approach an option in resection of advanced gastric cancer?, B. Castro, M. Aral, A. Fareleira, J. Costa-Maia, H. Santos-Sousa

  9. Diseases of the Esophagus (2016), 29(S1): RA06.01, Lessons from a quarter of century treating esophageal perforations: a proposal of a decision-making algorithm, H. Santos- Sousa, M. Aral, P. Salvador, J. Preto, A. Gouveia, J. Barbosa, J. Costa-Maia

  10. Diseases of the Esophagus (2016), 29(S1): RA06.02, Management of esophageal perforation: validation of a severity score, H. Santos-Sousa, M. Aral, P. Salvador, J. Preto, A. Gouveia, J. Barbosa, J. Costa-Maia

  11. Diseases of the Esophagus (2016), 29(S1): PS01.194, Is minimally invasive esophagectomy oncologically safe? Results of a case-control study, H. Santos-Sousa, M. Aral, V. Devezas, M. Mesquita, J. Preto, A. Gouveia, J. Barbosa, J. Costa-Maia

  12. J Clin Oncol (2016), 34(S4): Abstr 171, Outcomes of minimally invasive versus open esophagectomy for esophageal cancer: A single-center case-control study, H Santos- Sousa, M Mesquita, M Aral, J Costa-Maia

  13. Annals of Oncology (2014), 25 (S2): ii14–ii104, Minimally invasive esophagectomy: the new paradigm?, H Santos-Sousa, E Lima-da-Costa, J Preto, A Gouveia, S Carneiro, J Barbosa, J Costa-Maia

  14. Gastroenterology (2013), 144(S1): S1136, Mesothelin Expression and its Clinicopathological and Prognostic Significance in Gastric and Gastro-Esophageal Junction Cancer, H Santos-Sousa, L Marcos-Silva, J Pinto-de-Sousa, L David, J Costa-Maia

  15. Gastroenterology (2012), 142(S1): S1095, Esophageal perforation: Review of outcomes from a single-institution series, H Santos-Sousa, T Bouca-Machado, A Dubecz, A Gonçalves, J Preto, J Barbosa, J Costa-Maia

  16. J Clin Oncol (2011), 29(S4): 62, O-glicosylation alterations of proteins in gastric carcinoma, H Santos-Sousa, T Bouca-Machado, E Lima-da-costa, J Pinto-de-Sousa, C Gomes, CA Reis, L David, J Costa-Maia

  17. J Clin Oncol (2011), 29(S4): 22, Early onset gastric cancer: a distinct clinical entity with a different prognosis?, H Santos-Sousa, T Bouca-Machado, E Lima-da-costa, J Pinto-de-Sousa, J Preto, J Sousa-Rodrigues, J Costa-Maia