Where Ideas grow
Catarina Leite Pereira
Research Scientist
Catarina is a Biology graduate from Faculdade de Ciências of Universidade do Porto. During her studies, she has developed a special interest for biomedical engineering and regeneration, which led her to the Biomedical Engineering Master program at Faculdade de Engenharia da Universidade do Porto. During her Master she has joined the team of Professor Mário Barbosa, and participated in the European Research Project DISC Regeneration; her work was focused on the production of polymeric nanoparticles for anti-inflammatory drug delivery in the intervertebral disc. In 2013, Catarina started her PhD in Biomedical Sciences at ICBAS, Universidade do Porto, and joined an AO Spine Research Project in collaboration with the Musculoskeletal Regeneration Program at the AO Research Institute Davos in Switzerland. During her PhD, she developed a chemoattractant delivery system for Mesenchymal Stem Cells recruitment towards the Intervertebral Disc and studied the role of the recruited cells in intervertebral disc regeneration, namely in the ECM production. Currently she collaborates in the European Project RESTORE.

Selected Publications

Cunha C., Almeida C.R., Almeida M.I., Silva A.M., Molinos M., Lamas S., Pereira C.L., Teixeira G.Q., Monteiro A.T., Santos S.G., Gonçalves R.M., Barbosa M.A.,
Systemic delivery of bone marrow mesenchymal stem cells for in situ intervertebral disc regeneration. Stem Cells Translational Medicine6(3):1029-1039, 2017. [Journal: Article] [CI: 17] [IF: 4,9]
DOI: 10.5966/sctm.2016-0033 SCOPUS: 85017568310.

Antunes J.C., Pereira C.L., Teixeira G.Q., Silva R.V., Caldeira J., Grad S., Gonçalves R.M., Barbosa M.A.,
Poly(γ-glutamic acid) and poly(γ-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc. Journal of Materials Science: Materials in Medicine28(1):, 2017. [Journal: Article] [CI: 16] [IF: 2,4]
DOI: 10.1007/s10856-016-5787-1 SCOPUS: 84996606963.

Pereira C.L., Teixeira G.Q., Ribeiro-Machado C., Caldeira J., Costa M., Figueiredo F., Fernandes R., Aguiar P., Grad S., Barbosa M.A., Goncalves R.M.,
Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling. Scientific Reports6:, 2016. [Journal: Article] [CI: 24] [IF: 4,3]
DOI: 10.1038/srep33836 SCOPUS: 84988672665.

Teixeira G.Q., Boldt A., Nagl I., Pereira C.L., Benz K., Wilke H.J., Ignatius A., Barbosa M.A., Gonçalves R.M., Neidlinger-Wilke C.,
A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy. Tissue Engineering - Part C: Methods22(1):8-19, 2016. [Journal: Article] [CI: 21]
DOI: 10.1089/ten.tec.2015.0195 SCOPUS: 84954326138.

Teixeira G.Q., Leite Pereira C., Castro F., Ferreira J.R., Gomez-Lazaro M., Aguiar P., Barbosa M.A., Neidlinger-Wilke C., Goncalves R.M.,
Anti-inflammatory Chitosan/Poly-γ-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc. Acta Biomaterialia42:168-179, 2016. [Journal: Article] [CI: 35] [IF: 6,3]
DOI: 10.1016/j.actbio.2016.06.013 SCOPUS: 84983262266.

Antunes J.C., Tsaryk R., Gonçalves R.M., Pereira C.L., Landes C., Brochhausen C., Ghanaati S., Barbosa M.A., Kirkpatrick C.J.,
Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells. Tissue Engineering - Part A21(11-12):1869-1885, 2015. [Journal: Article] [CI: 8] [IF: 4,7 (*)]
DOI: 10.1089/ten.tea.2014.0386 SCOPUS: 84930157502.

Gonçalves R.M., Pereira A.C.L., Pereira I.O., Oliveira M.J., Barbosa M.A.,
Macrophage response to chitosan/poly-(γ-glutamic acid) nanoparticles carrying an anti-inflammatory drug. Journal of Materials Science: Materials in Medicine26(4):, 2015. [Journal: Article] [CI: 17] [IF: 2,3]
DOI: 10.1007/s10856-015-5496-1 SCOPUS: 84925061574.

Pereira C.L., Gonçalves R.M., Peroglio M., Pattappa G., D'Este M., Eglin D., Barbosa M.A., Alini M., Grad S.,
The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs. Biomaterials35(28):8144-8153, 2014. [Journal: Article] [CI: 58] [IF: 8,6]
DOI: 10.1016/j.biomaterials.2014.06.017 SCOPUS: 84903746142.

Pereira C.L., Antunes J.C., Gonçalves R.M., Ferreira-Da-Silva F., Barbosa M.A.,
Biosynthesis of highly pure poly-γ-glutamic acid for biomedical applications. Journal of Materials Science: Materials in Medicine23(7):1583-1591, 2012. [Journal: Article] [CI: 19] [IF: 2,1]
DOI: 10.1007/s10856-012-4639-x SCOPUS: 84863314791.

Antunes J.C., Pereira C.L., Molinos M., Ferreira-Da-Silva F., Dessi M., Gloria A., Ambrosio L., Goncalves R.M., Barbosa M.A.,
Layer-by-layer self-assembly of chitosan and poly(γ-glutamic acid) into polyelectrolyte complexes. Biomacromolecules12(12):4183-4195, 2011. [Journal: Article] [CI: 83] [IF: 5,5]
DOI: 10.1021/bm2008235 SCOPUS: 84856258191.