Where Ideas Grow
Vítor Teixeira
Junior Researcher

Vitor Teixeira graduated in Biochemistry and completed a PhD degree in Biomedical Sciences in 2015 from the University of Porto. Vitor published 14 papers and conference papers in peer-reviewed journals with over 800 citations overall (h-index=10). During his PhD degree, Vitor officially supervised 1 undergraduate and 1 MSc student that contributed to the publication of 4 first-author and 3 co-author research papers issued in high impact journals. This work led to greater understanding of sphingolipid functions and metabolism, ranging from the fundamental changes that occur in aged and diseased cells to pave avenues for novel strategies for treatment. This work was awarded with travel grants for lecture plenaries in high-level conferences (FEBS/EMBO Young Scientist Forum Prize 2014). In 2016, Vitor Teixeira got a highly competitive ERC-funded fellowship to perform postdoctoral work at the Sir William Dunn School of Pathology (University of Oxford, UK) in lipid droplet (LD) biology for 1.5 years. Here, he supervised 1 MSc student and the work resulted in 1 high-impact publication in the Journal of Cell Biology highlighted in the Phenotype journal issued by the Oxford University Biochemical Society. In this year, Vitor was awarded with the 2016 Invitrogen Science Hero Renaissance Man Award by Invitrogen/Thermo Fisher Scientific, an international award attributed to the scientist with the most well-rounded knowledge of all areas of science (not just the area of expertise), and willing to share and apply that information to the lab techniques. Overall, the professional network comprises more than 50 investigators around the world who contributed to past and undergoing projects. I participated as an Associate Researcher in six national (Portuguese Foundation for Science and Technology, Portugal) and international (European Research Council; FP7-ERC-SG-LS3 - ERC Starting Grant; 1,5 million euros; Project DROPFAT). Since 2019, he is an Assistant Professor at ICBAS (Abel Salazar Biomedical Sciences Institute, Medical School) and secured an over 100,000 euro funded project to hold a position as Fundação para a Ciência e Tecnologia (FCT) Junior Investigator position at i3s and established an independent line of research related to lipid droplet biology and neurodegeneration, having supervised so far 1 BSc, 1 MSc and 1 PhD students. Here, my strategy constitutes a systematic analysis of LD dynamics and will lead to significant insight into the mechanisms of cellular energy storage, thus offering a better understanding of disease, such as obesity, motor neuron and metabolic diseases. In 2020, I was selected (among 660 participants worldwide) to take part in the 70th Lindau Nobel Laureate Meeting, that brings together Nobel laureates and young scientists to foster scientific exchange. I also became a contracted Peer Reviewer of the Science Fund of the Republic of Serbia and Reviewer for ANR (fr: National Agency for Research of France). In 2021, Vitor joined the Editorial Board of MDPI-IJMS (International Journal of Molecular Sciences) of the Biochemistry Section as a Topic Academic Editor, having successfully launched a Special Issue. He also joined and contributes to the European-funded project PhaseAGE (https://cordis.europa.eu/project/id/725836), which aims to establish a research and innovation hub in the emerging field of biomolecular phase transitions in aging and age-related disorders, placing i3S at the forefront of this field. The main goal of the PhasAGE project is to implement a European Hub of Excellence in research and training on biomolecular phase transitions in aging and age-related disorders. He nows supervise 1 MSc student within the scope of this project, where we study the formation of membrane-less organelles or liquid-liquid phase separation (LLPS) structures containing aggregation-prone proteins in order to define the implications for neurodegeneration.

Selected Publications

Teixeira V., Maciel P., Costa V.,
Leading the way in the nervous system: Lipid Droplets as new players in health and disease. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1866(1):, 2021. [Journal: Review] [IF: 4,5 (*)]
DOI: 10.1016/j.bbalip.2020.158820 SCOPUS: 85092135819.

Teixeira V., Johnsen L., Martínez-Montañés F., Grippa A., Buxó L., Idrissi F.Z., Ejsing C.S., Carvalho P.,
Regulation of lipid droplets by metabolically controlled Ldo isoforms. Journal of Cell Biology217(1):127-138, 2018. [Journal: Article] [CI: 33] [IF: 8,9]
DOI: 10.1083/jcb.201704115 SCOPUS: 85039869347.

Teixeira V., Costa V.,
Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism. Progress in Lipid Research61:109-133, 2016. [Journal: Review] [CI: 20] [IF: 10,6]
DOI: 10.1016/j.plipres.2015.11.001 SCOPUS: 84952328556.

Teixeira V., Medeiros T.C., Vilaça R., Ferreira J., Moradas-Ferreira P., Costa V.,
Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1861(1):21-33, 2016. [Journal: Article] [CI: 10] [IF: 5,5]
DOI: 10.1016/j.bbalip.2015.10.004 SCOPUS: 84944937082.