Where Ideas grow
Vítor Teixeira
Research Scientist

Vitor Teixeira graduated in Biochemistry and completed a PhD degree in Biomedical Sciences in 2015 from the University of Porto. Vitor published 13 papers in peer-reviewed journals with over 700 citations overall (h-index=10;GS). During his PhD degree, Vitor´s work led to greater understanding of sphingolipid functions and metabolism, ranging from the fundamental changes that occur in aged and diseased cells to pave avenues for novel strategies for treatment. This work was awarded with travel grants for lecture plenaries in high-level conferences (FEBS/EMBO Young Scientist Forum Prize 2014). In 2016, Vitor Teixeira got a highly competitive ERC-funded fellowship to perform postdoctoral work at the Sir William Dunn School of Pathology (University of Oxford, UK) in lipid droplet biology. Here, he made part of the post-doctoral association for science management, contributing to organize and provide a basis for scientific and personal exchange. The work resulted in 1 high-impact publication in the Journal of Cell Biology highlighted in the Phenotype journal issued by the Oxford University Biochemical Society. In this year, Vitor was awarded with the 2016 Invitrogen Science Hero Renaissance Man Award by Invitrogen/Thermo Fisher Scientific, an international award attributed to the scientist with the most well-rounded knowledge of all areas of science (not just the area of expertise), and willing to share and apply that information to the lab techniques. Overall, the professional network comprises more than 50 investigators around the world who contributed to past and undergoing projects. I participated as an Associate Researcher in six national (Portuguese Foundation for Science and Technology, Portugal) and international (European Research Council; FP7-ERC-SG-LS3 - ERC Starting Grant; 1,5 million euros; Project DROPFAT). Since 2019, he is an Assistant Professor at ICBAS (Abel Salazar Biomedical Sciences Institute, Medical School) and secured an over 100,000 euro funded project to hold a position as Fundação para a Ciência e Tecnologia (FCT) Junior Investigator position at i3s. Here, my strategy constitutes a systematic analysis of LD dynamics and will lead to significant insight into the mechanisms of cellular energy storage, thus offering a better understanding of disease, such as obesity, motor neuron and metabolic diseases. This will be the ideal platform to advance biomedical research toward the UN 2030 Agenda mission of eradicating disease and promote well-being for all (Goal 3). For the project, we will use innovative biochemistry, molecular and cell biology and proteomics/lipidomics techniques and these will be of tremendous use to others as well, eventually contributing to foster synergy with other groups to validate our findings in different model systems.. Thus, the results of work will be of general interest and we will aim to publish our findings in high-impact journals and actively communicate the broader implications to the public. In 2020, I was selected (660 participants worldwide) to take part in the 70th Lindau Nobel Laureate Meeting, that brings together Nobel laureates and young scientists to foster scientific exchange.

Selected Publications

Teixeira V., Maciel P., Costa V.,
Leading the way in the nervous system: Lipid Droplets as new players in health and disease. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1866(1):, 2021. [Journal: Review] [IF: 4,5 (*)]
DOI: 10.1016/j.bbalip.2020.158820 SCOPUS: 85092135819.

Teixeira V., Johnsen L., Martínez-Montañés F., Grippa A., Buxó L., Idrissi F.Z., Ejsing C.S., Carvalho P.,
Regulation of lipid droplets by metabolically controlled Ldo isoforms. Journal of Cell Biology217(1):127-138, 2018. [Journal: Article] [CI: 33] [IF: 8,9]
DOI: 10.1083/jcb.201704115 SCOPUS: 85039869347.

Teixeira V., Costa V.,
Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism. Progress in Lipid Research61:109-133, 2016. [Journal: Review] [CI: 20] [IF: 10,6]
DOI: 10.1016/j.plipres.2015.11.001 SCOPUS: 84952328556.

Teixeira V., Medeiros T.C., Vilaça R., Ferreira J., Moradas-Ferreira P., Costa V.,
Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1861(1):21-33, 2016. [Journal: Article] [CI: 10] [IF: 5,5]
DOI: 10.1016/j.bbalip.2015.10.004 SCOPUS: 84944937082.