Ana do Vale
Fish Immunology & Vaccinology
Associate Researcher
Ana do Vale graduated in Aquatic Sciences from the University of Porto in 1996 and received her PhD from the same University in 2003. Her research has been conducted at IBMC, as well as at the University of Santiago de Compostela (Spain) and Marine Laboratory (Aberdeen, UK) and has been focusing on understanding bacterial virulence mechanisms relying on protein toxins. Ana do Vale has experience in supervising undergraduate, MsC and PhD students and in running research projects.
Selected Publications
Freitas I.L., Teixeira A., Loureiro I., Lisboa J., Saraiva A., Dos Santos N.M.S., Do Vale A.,
Lisboa J., Pereira C., Rifflet A., Ayala J., Terceti M.S., Barca A.V., Rodrigues I., Pereira P.J.B., Osorio C.R., Portillo F.G.d., Boneca I.G., Vale A.d., Santos N.M.S.d.,
Pereira C., Rodrigues I.S., Pereira L.M.G., Lisboa J., Pinto R.D., Araújo L., Oliveira P., Benz R., dos Santos N.M.S., do Vale A.,
Rodrigues I.S., Pereira L.M.G., Lisboa J., Pereira C., Oliveira P., dos Santos N.M.S., do Vale A.,
do Vale A., Pereira C., Osorio C.R., dos Santos N.M.S.,
Pereira L.M.G., Pinto R.D., Silva D.S., Moreira A.R., Beitzinger C., Oliveira P., Sampaio P., Benz R., Azevedo J.E., dos Santos N.M.S., do Vale A.,
Silva D.S., Pereira L.M.G., Moreira A.R., Ferreira-da-Silva F., Brito R.M., Faria T.Q., Zornetta I., Montecucco C., Oliveira P., Azevedo J.E., Pereira P.J.B., Macedo-Ribeiro S., do Vale A., dos Santos N.M.S.,
Susceptibility of Sea Bream (Sparus aurata) to AIP56, an AB-Type Toxin Secreted by Photobacterium damselae subsp. piscicida. Toxins14(2):, 2022. [Journal: Article] [CI: 4] [IF: 4,2]
DOI: 10.3390/toxins14020119 SCOPUS: 85124209860.
DOI: 10.3390/toxins14020119 SCOPUS: 85124209860.
Lisboa J., Pereira C., Rifflet A., Ayala J., Terceti M.S., Barca A.V., Rodrigues I., Pereira P.J.B., Osorio C.R., Portillo F.G.d., Boneca I.G., Vale A.d., Santos N.M.S.d.,
A Secreted NlpC/P60 Endopeptidase from Photobacterium damselae subsp. piscicida Cleaves the Peptidoglycan of Potentially Competing Bacteria. mSphere6(1):1-23, 2021. [Journal: Article] [CI: 3] [IF: 5]
DOI: 10.1128/mSphere.00736-20 SCOPUS: 85101242554.
DOI: 10.1128/mSphere.00736-20 SCOPUS: 85101242554.
Pereira C., Rodrigues I.S., Pereira L.M.G., Lisboa J., Pinto R.D., Araújo L., Oliveira P., Benz R., dos Santos N.M.S., do Vale A.,
Role of AIP56 disulphide bond and its reduction by cytosolic redox systems for efficient intoxication. Cellular Microbiology22(1):, 2020. [Journal: Article] [CI: 3] [IF: 3,7]
DOI: 10.1111/cmi.13109 SCOPUS: 85073780861.
DOI: 10.1111/cmi.13109 SCOPUS: 85073780861.
Rodrigues I.S., Pereira L.M.G., Lisboa J., Pereira C., Oliveira P., dos Santos N.M.S., do Vale A.,
Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida. Scientific Reports9(1):, 2019. [Journal: Article] [CI: 5] [IF: 4]
DOI: 10.1038/s41598-019-45240-w SCOPUS: 85067826636.
DOI: 10.1038/s41598-019-45240-w SCOPUS: 85067826636.
do Vale A., Pereira C., Osorio C.R., dos Santos N.M.S.,
The apoptogenic toxin aip56 is secreted by the type ii secretion system of photobacterium damselae subsp. Piscicida. Toxins9(11):, 2017. [Journal: Article] [CI: 13] [IF: 3,3]
DOI: 10.3390/toxins9110368 SCOPUS: 85034449974.
DOI: 10.3390/toxins9110368 SCOPUS: 85034449974.
Pereira L.M.G., Pinto R.D., Silva D.S., Moreira A.R., Beitzinger C., Oliveira P., Sampaio P., Benz R., Azevedo J.E., dos Santos N.M.S., do Vale A.,
Intracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicida. Infection and Immunity82(12):5270-5285, 2014. [Journal: Article] [CI: 15] [IF: 3,7]
DOI: 10.1128/IAI.02623-14 SCOPUS: 84911433340.
DOI: 10.1128/IAI.02623-14 SCOPUS: 84911433340.
Silva D.S., Pereira L.M.G., Moreira A.R., Ferreira-da-Silva F., Brito R.M., Faria T.Q., Zornetta I., Montecucco C., Oliveira P., Azevedo J.E., Pereira P.J.B., Macedo-Ribeiro S., do Vale A., dos Santos N.M.S.,
The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-κb P65. PLoS Pathogens9(2):, 2013. [Journal: Article] [CI: 37] [IF: 8,1]
DOI: 10.1371/journal.ppat.1003128 SCOPUS: 84880954175.
DOI: 10.1371/journal.ppat.1003128 SCOPUS: 84880954175.