Where Ideas Grow
Mónica Sousa
Group leader

Monica M Sousa graduated in Biochemistry and holds a PhD in Biomedical Sciences from the University of Porto. During her PhD she studied the biology of transthyretin, an aggregation-prone protein, and generated mouse models for familial amyloid polyneuropathy. As a postdoctoral fellow, Monica was a visiting scientist at the Department of Pathology, Columbia University- New York, where she studied neurodegeneration caused by amyloid fibrils. Currently her group is focused on the analysis of cytoskeleton organization and dynamics during axon growth and regeneration. Since 2010 Monica is a vice-director of the Instituto de Biologia Molecular e Celular- IBMC.

Selected Publications

Franquinho F., Nogueira-Rodrigues J., Duarte J.M., Esteves S.S., Carter-Su C., Monaco A.P., Molnár Z., Velayos-Baeza A., Brites P., Sousa M.M.,
The dyslexia-susceptibility protein kiaa0319 inhibits axon growth through smad2 signaling. Cerebral cortex (New York, N.Y. : 1991)27(3):1732-1747, 2017. [Journal: Article] [CI: 13] [IF: 6,3]
DOI: 10.1093/cercor/bhx023 SCOPUS: 85021858395.

Leite S.C., Sampaio P., Sousa V.F., Nogueira-Rodrigues J., Pinto-Costa R., Peters L.L., Brites P., Sousa M.M.,
The Actin-Binding Protein a-Adducin Is Required for Maintaining Axon Diameter. Cell Reports15(3):490-498, 2016. [Journal: Article] [CI: 53] [IF: 8,3]
DOI: 10.1016/j.celrep.2016.03.047 SCOPUS: 84962762309.

Liz M.A., Mar F.M., Santos T.E., Pimentel H.I., Marques A.M., Morgado M.M., Vieira S., Sousa V.F., Pemble H., Wittmann T., Sutherland C., Woodgett J.R., Sousa M.M.,
Neuronal deletion of GSK3ß increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. BMC Biology12(1):, 2014. [Journal: Article] [CI: 50] [IF: 8]
DOI: 10.1186/1741-7007-12-47 SCOPUS: 84927941057.

Mar F.M., Simões A.R., Leite S., Morgado M.M., Santos T.E., Rodrigo I.S., Teixeira C.A., Misgeld T., Sousa M.M.,
CNS axons globally increase axonal transport after peripheral conditioning. Journal of Neuroscience34(17):5965-5970, 2014. [Journal: Article] [CI: 49] [IF: 6,3]
DOI: 10.1523/JNEUROSCI.4680-13.2014 SCOPUS: 84899493785.

Da Silva T.F., Eira J., Lopes A.T., Malheiro A.R., Sousa V., Luoma A., Avila R.L., Wanders R.J.A., Just W.W., Kirschner D.A., Sousa M.M., Brites P.,
Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination. Journal of Clinical Investigation124(6):2560-2570, 2014. [Journal: Article] [CI: 59] [IF: 13,2]
DOI: 10.1172/JCI72063 SCOPUS: 84902172153.