creating a
healthier future
Manuel Vilanova
Group leader

Manuel Vilanova graduated in Biochemistry by the University of Porto in 1988 and defended the PhD thesis in Biomedical Sciences at ICBAS-U.Porto in 1999. He is Full Professor of Immunology since 2023 at this Institute, teaching in the fields of immunology and infection and heads the Immunobiology group of IBMC/i3S since 2005. His studies particularly addressed immunobiological mechanisms operating in hosts infected with pathogens with high impact in human or animal health, such as Candida albicans, Staphylococcus epidermidis and Neospora caninum. He authored more than 100 peer-reviewed articles, book chapters and patents. Manuel Vilanova presided the Portuguese Society of Immunology in 2012-2015.

Selected Publications

Dias A.M., Correia A., Pereira M.S., Almeida C.R., Alves I., Pinto V., Catarino T.A., Mendes N., Leander M., Teresa Oliva-Teles M., Maia L., Delerue-Matos C., Taniguchi N., Lima M., Pedroto I., Marcos-Pinto R., Lago P., Reis C.A., Vilanova M., Pinho S.S.,
Metabolic control of T cell immune response through glycans in inflammatory bowel disease. Proceedings of the National Academy of Sciences of the United States of America115(20):E4651-E4660, 2018. [Journal: Article] [CI: 71] [IF: 9,6]
DOI: 10.1073/pnas.1720409115 SCOPUS: 85046964805.

Teixeira L., Marques R.M., Ferreirinha P., Bezerra F., Melo J., Moreira J., Pinto A., Correia A., Ferreira P.G., Vilanova M.,
Enrichment of IFN-γ producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite. Scientific Reports6:, 2016. [Journal: Article] [CI: 16] [IF: 4,3]
DOI: 10.1038/srep23475 SCOPUS: 84961589792.

Ferreirinha P., Pérez-Cabezas B., Correia A., Miyazawa B., França A., Carvalhais V., Faustino A., Cordeiro-da-Silva A., Teixeira L., Pier G.B., Cerca N., Vilanova M.,
Poly-N-acetylglucosamine production by Staphylococcus epidermidis cells increases their in vivo proinflammatory effect. Infection and Immunity84(10):2933-2943, 2016. [Journal: Article] [CI: 8] [IF: 3,6]
DOI: 10.1128/IAI.00290-16 SCOPUS: 84994337344.

França A., Pérez-Cabezas B., Correia A., Pier G.B., Cerca N., Vilanova M.,
Staphylococcus epidermidis biofilm-released cells induce a prompt and more marked in vivo inflammatory-type response than planktonic or biofilm cells. Frontiers in Microbiology7(SEP):, 2016. [Journal: Article] [CI: 11] [IF: 4,1]
DOI: 10.3389/fmicb.2016.01530 SCOPUS: 84994047695.

Teixeira L., Moreira J., Melo J., Bezerra F., Marques R.M., Ferreirinha P., Correia A., Monteiro M.P., Ferreira P.G., Vilanova M.,
Immune response in the adipose tissue of lean mice infected with the protozoan parasite Neospora caninum. Immunology145(2):242-257, 2015. [Journal: Article] [CI: 17] [IF: 4,1]
DOI: 10.1111/imm.12440 SCOPUS: 84929659325.

Ferreira S.S., Passos C.P., Madureira P., Vilanova M., Coimbra M.A.,
Structure-function relationships of immunostimulatory polysaccharides: A review. Carbohydrate Polymers132:378-396, 2015. [Journal: Review] [CI: 699] [IF: 4,2]
DOI: 10.1016/j.carbpol.2015.05.079 SCOPUS: 84934765169.

Correia A., Ferreirinha P., Botelho S., Belinha A., Leitão C., Caramalho I., Teixeira L., González-Fernandéz A., Appelberg R., Vilanova M.,
Predominant role of interferon-γ 3 in the host protective effect of CD8 + T cells against Neospora caninum infection. Scientific Reports5:1-14, 2015. [Journal: Article] [CI: 16] [IF: 5,2]
DOI: 10.1038/srep14913 SCOPUS: 84943770641.

Ferreirinha P., Dias J., Correia A., Pérez-Cabezas B., Santos C., Teixeira L., Ribeiro A., Rocha A., Vilanova M.,
Protective effect of intranasal immunization with Neospora caninum membrane antigens against murine neosporosis established through the gastrointestinal tract. Immunology141(2):256-267, 2014. [Journal: Article] [CI: 15] [IF: 3,8]
DOI: 10.1111/imm.12191 SCOPUS: 84891893462.

Madureira P., Andrade E.B., Gama B., Oliveira L., Moreira S., Ribeiro A., Correia-Neves M., Trieu-Cuot P., Vilanova M., Ferreira P.,
Inhibition of IL-10 production by maternal antibodies against group b streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. PLoS Pathogens7(11):, 2011. [Journal: Article] [CI: 39] [IF: 9,1]
DOI: 10.1371/journal.ppat.1002363 SCOPUS: 81755177757.

Correia A., Lermann U., Teixeira L., Cerca F., Botelho S., Gil Da Costa R.M., Sampaio P., Gärtner F., Morschhäuser J., Vilanova M., Pais C.,
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis. Infection and Immunity78(11):4839-4849, 2010. [Journal: Article] [CI: 72] [IF: 4,1]
DOI: 10.1128/IAI.00248-10 SCOPUS: 78049434544.