creating a
healthier future
Manuel Vilanova
Group leader

Manuel Vilanova graduated in Biochemistry from the University of Porto in 1988 and defended his doctoral thesis in Biomedical Sciences at ICBAS-U. Porto in 1999. He is a Full Professor of Immunology at this Institute, since 2023, teaching in the areas of immunology and infection. He has led the Immunobiology group at IBMC/i3S since 2005. His studies have particularly addressed the immunobiological mechanisms operating in hosts infected with pathogens with high impact on human and animal health, such as Candida albicans, Staphylococcus epidermidis and Neospora caninum. He has authored over a hundred publications, including peer-reviewed articles, book chapters and patents. He has supervised/co-supervised more than 30 doctoral students. Manuel Vilanova was president of the Portuguese Society of Immunology between 2012 and 2015.

Selected Publications

Dias A.M., Correia A., Pereira M.S., Almeida C.R., Alves I., Pinto V., Catarino T.A., Mendes N., Leander M., Teresa Oliva-Teles M., Maia L., Delerue-Matos C., Taniguchi N., Lima M., Pedroto I., Marcos-Pinto R., Lago P., Reis C.A., Vilanova M., Pinho S.S.
Metabolic control of T cell immune response through glycans in inflammatory bowel disease. Proceedings of the National Academy of Sciences of the United States of America115(20):E4651-E4660, 2018. [Journal: Article] [CI: 81] [IF: 9,6]
DOI: 10.1073/pnas.1720409115 SCOPUS: 85046964805

Teixeira L., Marques R.M., Ferreirinha P., Bezerra F., Melo J., Moreira J., Pinto A., Correia A., Ferreira P.G., Vilanova M.
Enrichment of IFN-γ producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite. Scientific Reports6:, 2016. [Journal: Article] [CI: 17] [IF: 4,3]
DOI: 10.1038/srep23475 SCOPUS: 84961589792

Ferreirinha P., Pérez-Cabezas B., Correia A., Miyazawa B., França A., Carvalhais V., Faustino A., Cordeiro-da-Silva A., Teixeira L., Pier G., Cerca N., Vilanova M.
Poly-N-acetylglucosamine production by Staphylococcus epidermidis cells increases their in vivo proinflammatory effect. Infection and Immunity84(10):2933-2943, 2016. [Journal: Article] [CI: 10] [IF: 3,6]
DOI: 10.1128/IAI.00290-16 SCOPUS: 84994337344

França A., Pérez-Cabezas B., Correia A., Pier G., Cerca N., Vilanova M.
Staphylococcus epidermidis biofilm-released cells induce a prompt and more marked in vivo inflammatory-type response than planktonic or biofilm cells. Frontiers in Microbiology7(SEP):, 2016. [Journal: Article] [CI: 14] [IF: 4,1]
DOI: 10.3389/fmicb.2016.01530 SCOPUS: 84994047695

Teixeira L., Moreira J., Melo J., Bezerra F., Marques R.M., Ferreirinha P., Correia A., Monteiro M.P., Ferreira P.G., Vilanova M.
Immune response in the adipose tissue of lean mice infected with the protozoan parasite Neospora caninum. Immunology145(2):242-257, 2015. [Journal: Article] [CI: 18] [IF: 4,1]
DOI: 10.1111/imm.12440 SCOPUS: 84929659325

Ferreira S.S., Passos C.P., Madureira P., Vilanova M., Coimbra M.A.
Structure-function relationships of immunostimulatory polysaccharides: A review. Carbohydrate Polymers132:378-396, 2015. [Journal: Review] [CI: 800] [IF: 4,2]
DOI: 10.1016/j.carbpol.2015.05.079 SCOPUS: 84934765169

Correia A., Ferreirinha P., Botelho S., Belinha A., Leitão C., Caramalho I., Teixeira L., González-Fernandéz A., Appelberg R., Vilanova M.
Predominant role of interferon-γ 3 in the host protective effect of CD8 + T cells against Neospora caninum infection. Scientific Reports5:1-14, 2015. [Journal: Article] [CI: 16] [IF: 5,2]
DOI: 10.1038/srep14913 SCOPUS: 84943770641

Ferreirinha P., Dias J., Correia A., Pérez-Cabezas B., Santos C., Teixeira L., Ribeiro A., Rocha A., Vilanova M.
Protective effect of intranasal immunization with Neospora caninum membrane antigens against murine neosporosis established through the gastrointestinal tract. Immunology141(2):256-267, 2014. [Journal: Article] [CI: 16] [IF: 3,8]
DOI: 10.1111/imm.12191 SCOPUS: 84891893462

Madureira P., Andrade E.B., Gama B., Oliveira L., Moreira S., Ribeiro A., Correia-Neves M., Trieu-Cuot P., Vilanova M., Ferreira P.
Inhibition of IL-10 production by maternal antibodies against group b streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. PLoS Pathogens7(11):, 2011. [Journal: Article] [CI: 44] [IF: 9,1]
DOI: 10.1371/journal.ppat.1002363 SCOPUS: 81755177757

Correia A., Lermann U., Teixeira L., Cerca F., Botelho S., Gil Da Costa R.M., Sampaio P., Gärtner F., Morschhäuser J., Vilanova M., Pais C.
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis. Infection and Immunity78(11):4839-4849, 2010. [Journal: Article] [CI: 77] [IF: 4,1]
DOI: 10.1128/IAI.00248-10 SCOPUS: 78049434544