Where Ideas Grow
Amélia Sarmento
Senior Researcher
In 1987 I graduated on Biochemistry at University of Porto, Portugal. I worked as a research fellow at the Centre for Experimental Cytology (Porto) and also did my PhD there with Manuel T. Silva as supervisor and Rui Appelberg as co-supervisor, on Mycobacterium avium - macrophage interplay in a mouse model of infection. I completed my PhD in 1997 and then paused my research activity for some years as my children were born and I wanted to be more present. From 2001-2004 I worked on a post-doc project about the effects of mercury exposure on the activity of sea bass (Dicentrarchus labrax) macrophages, at IBMC - Instituto de Biologia Molecular e Celular (Porto). At the end of 2004 I was admitted as an Assistant Professor at University Fernando Pessoa (Porto) and at 2006 I started working in Mycobacterium avium paratuberculosis and Crohn's disease, particularly at the level of mycobacterium-macrophage interaction. From 2009-2012 I was principal investigator in a research project entitled "Mycobacterial infection in Crohn's disease". The results are included in four published papers.

Selected Publications

Sarmento A.,
Editorial: Understanding crohn's disease: Immunity, genes and microbes. Frontiers in Immunology8(MAR):, 2017. [Journal: Editorial] [CI: 3] [IF: 5,5]
DOI: 10.3389/fimmu.2017.00357 SCOPUS: 85017094130.

Nazareth N., Magro F., Machado E., Ribeiro T.G., Martinho A., Rodrigues P., Alves R., Macedo G.N., Gracio D., Coelho R., Abreu C., Appelberg R., Dias C., Macedo G., Bull T., Sarmento A.,
Prevalence of Mycobacterium avium subsp. paratuberculosis and Escherichia coli in blood samples from patients with inflammatory bowel disease. Medical Microbiology and Immunology204(6):681-692, 2015. [Journal: Article] [CI: 27] [IF: 2,3]
DOI: 10.1007/s00430-015-0420-3 SCOPUS: 84942193176.

Sousa T., Costa M., Sarmento P., Manso M.C., Abreu C., Bull T.J., Cabeda J., Sarmento A.,
Dna-based detection of mycobacterium avium subsp. Paratuberculosis in domestic and municipal water from porto (portugal), an area of high ibd prevalence. AIMS Microbiology7(2):163-174, 2021. [Journal: Article]
DOI: 10.3934/MICROBIOL.2021011 SCOPUS: 85109030567.

Nazareth N., Magro F., Appelberg R., Silva J., Gracio D., Coelho R., Cabral J.M., Abreu C., Macedo G., Bull T.J., Sarmento A.,
Increased viability but decreased culturability of Mycobacterium avium subsp. paratuberculosis in macrophages from inflammatory bowel disease patients under Infliximab treatment. Medical Microbiology and Immunology204(6):647-656, 2015. [Journal: Article] [CI: 7] [IF: 2,3]
DOI: 10.1007/s00430-015-0393-2 SCOPUS: 84942197352.

Nazareth N., Magro F., Silva J., Duro M., Gracio D., Coelho R., Appelberg R., Macedo G., Sarmento A.,
Infliximab therapy increases the frequency of circulating CD16+ monocytes and modifies macrophage cytokine response to bacterial infection. Clinical and Experimental Immunology177(3):703-711, 2014. [Journal: Article] [CI: 17] [IF: 3]
DOI: 10.1111/cei.12375 SCOPUS: 84904751087.