Pedro Granja

Biofabrication

Group leader

Pedro L. Granja was born in 1970, in Porto, Portugal. His high school studies took place in Porto, (Portugal) and São Paulo (Brazil). He graduated in Metallurgical Engineering at the Univ. Porto (UP) in 1993 and obtained his PhD in Engineering Sciences from UP in 2001, as a result of studies carried out at Instituto de Engenharia Biomédica (INEB, UP) and INSERM U.443(Univ. Bordeaux, France). He carried out post-doctoral studies at INEB, was visiting scientist at the Univ. Michigan (USA, 2004) and Invited Professor at the Univ. Paris 13 (France, 2009). He is presentlyLeader of the Biofabrication Group at Instituto de Investigação e Inovação em Saúde(i3S, UP).

His research interests lie at the intersection between materials science, biology and medicine, namely on the development of biomaterials for biofabrication, using principles and tools from tissue engineering and regenerative medicine.His research work has been focused on the molecular design of biofunctional hydrogels as 3D biomimics of the extracellular matrix. Currently, he has been exploring the biofabrication of tissue constructs from cell-ladden hydrogels. He received the 2006 Jean Leray Award by the European Society for Biomaterials (ESB) and is internationally reputed as founder (1998) and Editor-in-Chief of the Biomaterials Network (Biomat.net). He was recentlydistinguished as Fellow of Biomaterials Science and Engineering (FSBE, 2020). Moreover, he serves as expert for several national and international funding agencies, organizations and companies. So far, he has authored more than 110 articles in international indexed journals, 11 book chapters, 2 patents and presented 170 invited lectures worldwide. At present, he has an h-index of 51 and his publications have been cited over 7700 times (Google Scholar).

Selected Publications

Pereira C., Ferreira D., Mendes N., Granja P.L., Almeida G.M., Oliveira C.,

Expression of CD44V6-containing isoforms influences cisplatin response in gastric cancer cells. Cancers12(4):, 2020. [Journal: Article] [CI: 10] [IF: 6,6]
DOI: 10.3390/cancers12040858 SCOPUS: 85083265801.

Neves S.C., Moroni L., Barrias C.C., Granja P.L.,

Leveling Up Hydrogels: Hybrid Systems in Tissue Engineering. Trends in Biotechnology38(3):292-315, 2020. [Journal: Review] [CI: 36] [IF: 19,5]
DOI: 10.1016/j.tibtech.2019.09.004 SCOPUS: 85075891574.

Costa-Almeida R., Granja P.L., Gomes M.E.,

Gravity, Tissue Engineering, and the Missing Link. Trends in Biotechnology36(4):343-347, 2018. [Journal: Short Survey] [CI: 6] [IF: 13,7]
DOI: 10.1016/j.tibtech.2017.10.017 SCOPUS: 85034606920.

Pereira R.F., Sousa A., Barrias C.C., Bártolo P.J., Granja P.L.,

A single-component hydrogel bioink for bioprinting of bioengineered 3D constructs for dermal tissue engineering. Materials Horizons5(6):1100-1111, 2018. [Journal: Article] [CI: 65] [IF: 14,4]
DOI: 10.1039/c8mh00525g SCOPUS: 85055847804.

Kennedy P.J., Oliveira C., Granja P.L., Sarmento B.,

Monoclonal antibodies: technologies for early discovery and engineering. Critical Reviews in Biotechnology38(3):394-408, 2018. [Journal: Review] [CI: 47] [IF: 7,1]
DOI: 10.1080/07388551.2017.1357002 SCOPUS: 85027194652.

Pereira R.F., Barrias C.C., Bártolo P.J., Granja P.L.,

Cell-instructive pectin hydrogels crosslinked via thiol-norbornene photo-click chemistry for skin tissue engineering. Acta Biomaterialia66:282-293, 2018. [Journal: Article] [CI: 94] [IF: 6,6]
DOI: 10.1016/j.actbio.2017.11.016 SCOPUS: 85034850058.

Lourenço B.N., dos Santos T., Oliveira C., Barrias C.C., Granja P.L.,

Bioengineering a novel 3D in vitro model of gastric mucosa for stomach permeability studies. Acta Biomaterialia82:68-78, 2018. [Journal: Article] [CI: 11] [IF: 6,6]
DOI: 10.1016/j.actbio.2018.10.007 SCOPUS: 85055110280.

Bauleth-Ramos T., Feijão T., Gonçalves A., Shahbazi M.A., Liu Z., Barrias C., Oliveira M.J., Granja P., Santos H.A., Sarmento B.,

Colorectal cancer triple co-culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles. Journal of Controlled Release323:398-411, 2020. [Journal: Article] [CI: 19] [IF: 9,8]
DOI: 10.1016/j.jconrel.2020.04.025 SCOPUS: 85084193413.

Bauleth-Ramos T., Shih T.Y., Shahbazi M.A., Najibi A.J., Mao A.S., Liu D., Granja P., Santos H.A., Sarmento B., Mooney D.J.,

Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination. Advanced Functional Materials29(35):, 2019. [Journal: Article] [CI: 30] [IF: 16,8]
DOI: 10.1002/adfm.201903686 SCOPUS: 85068179169.