João Barbosa

Cell Division & Genomic Stability

Post-doctoral Fellow

João Francisco Barbosa graduated with a degree in Biochemistry from the University of Porto and then moved to the Faculty of Sciences and Technology of the University of Coimbra where he got a Master's degree in Biochemistry. He then joined Prof. Claudio Sunkel's lab at IBMC, where he developed his PhD project, which was focused on the role of POLO kinase in the regulation of kinetochore-microtubule attachments during mitosis.

Selected Publications

Barbosa J., Sunkel C.E., Conde C.,

SPIN(DLY)-OFF: A tale of conformational change to control DYNEIN. Journal of Cell Biology221(11):, 2022. [Journal: Article] [IF: 7,8]
DOI: 10.1083/jcb.202209063 SCOPUS: 85139360830.

Barbosa J., Sunkel C.E., Conde C.,

The Role of Mitotic Kinases and the RZZ Complex in Kinetochore-Microtubule Attachments: Doing the Right Link. Frontiers in Cell and Developmental Biology10:, 2022. [Journal: Review] [CI: 3] [IF: 5,5]
DOI: 10.3389/fcell.2022.787294 SCOPUS: 85124610528.

Barbosa J., Conde C., Sunkel C.,

RZZ-SPINDLY-DYNEIN: you got to keep ‘em separated. Cell Cycle19(14):1716-1726, 2020. [Journal: Article] [CI: 4] [IF: 4,5]
DOI: 10.1080/15384101.2020.1780382 SCOPUS: 85086926601.

Barbosa J., Martins T., Bange T., Tao L., Conde C., Sunkel C.,

Polo regulates Spindly to prevent premature stabilization of kinetochore–microtubule attachments. EMBO Journal39(2):, 2020. [Journal: Article] [CI: 13] [IF: 11,6]
DOI: 10.15252/embj.2018100789 SCOPUS: 85076772192.

Cunha-Silva S., Osswald M., Goemann J., Barbosa J., Santos L.M., Resende P., Bange T., Ferrás C., Sunkel C.E., Conde C.,

Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. Journal of Cell Biology219(3):, 2020. [Journal: Article] [CI: 9] [IF: 10,5]
DOI: 10.1083/jcb.201906039 SCOPUS: 85077707501.

Moura M., Osswald M., Leça N., Barbosa J., Pereira A.J., Maiato H., Sunkel C.E., Conde C.,

Protein phosphatase 1 inactivates Mps1 to ensure efficient spindle assembly checkpoint silencing. eLife6:, 2017. [Journal: Article] [CI: 39] [IF: 7,6]
DOI: 10.7554/eLife.25366 SCOPUS: 85019849461.

Conde C., Osswald M., Barbosa J., Moutinho-Santos T., Pinheiro D., Guimarães S., Matos I., Maiato H., Sunkel C.E.,

Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation. EMBO Journal32(12):1761-1777, 2013. [Journal: Article] [CI: 37] [IF: 10,7]
DOI: 10.1038/emboj.2013.109 SCOPUS: 84879459640.