José das Neves

Nanomedicines & Translational Drug Delivery

Associate Researcher

José das Neves is Assistant Researcher at i3S/INEB since 2019. He graduated in Pharmaceutical Sciences (2003) and holds a MSc in Pharmaceutical Technology (2007) and a PhD in Pharmaceutical Sciences (2013) from the University of Porto, Portugal. Prior to engaging in a full-time research career, he worked as clinical pharmacist at the Hospital Geral de Sto. António, Portugal (2004-2009). José was a visiting researcher at Northeastern University (USA) in 2009-2010 and at the Institute of Tropical Medicine (Belgium) in 2010. After completing his PhD, he moved to INEB as a Postdoc/Junior Researcher (2014-2019). His broad research interest includes nanomedicine, drug delivery, and women's health. José's current research focuses specifically on the development of drug delivery strategies for the prevention or treatment of sexually transmitted infections and lower female genital tract diseases, and on new approaches for tackling mucosal barriers to the transport of nanocarriers. As of January 2024, he is the author of 82 peer-reviewed articles, 14 book chapters, and 87 presentations at scientific meetings. He is the co-Editor of 5 scientific books, Associate Editor of Frontiers in Pharmacology (Frontiers Media), and Editorial Board member of Biomedical Technology (KeAi/Elsevier), PLOS ONE (Public Library of Science), Pharmaceutics (MDPI), Nanomaterials (MDPI), 4Open (EDP Sciences) and Scientific Letters (CESPU). José is a member of the Board of the CRS Spanish-Portuguese Local Chapter. He is also an active collaborator of the Global Burden of Disease Study, contributing to 38 peer-reviewed articles from this international consortium.

Selected Publications

Cautela M.P., Moshe H., Sosnik A., Sarmento B., das Neves J.,

Composite films for vaginal delivery of tenofovir disoproxil fumarate and emtricitabine. European Journal of Pharmaceutics and Biopharmaceutics138:3-10, 2019. [Journal: Article] [CI: 30] [IF: 4,6]
DOI: 10.1016/j.ejpb.2018.02.001 SCOPUS: 85044614712.

Nunes R., Araújo F., Barreiros L., Bártolo I., Segundo M.A., Taveira N., Sarmento B., Das Neves J.,

Noncovalent PEG Coating of Nanoparticle Drug Carriers Improves the Local Pharmacokinetics of Rectal Anti-HIV Microbicides. ACS Applied Materials and Interfaces10(41):34942-34953, 2018. [Journal: Article] [CI: 28] [IF: 8,5]
DOI: 10.1021/acsami.8b12214 SCOPUS: 85054761997.

das Neves J., Notario-Pérez F., Sarmento B.,

Women-specific routes of administration for drugs: A critical overview. Advanced Drug Delivery Reviews176:, 2021. [Journal: Review] [CI: 16] [IF: 17,9]
DOI: 10.1016/j.addr.2021.113865 SCOPUS: 85110597388.

Talebian S., Rodrigues T., Das Neves J., Sarmento B., Langer R., Conde J.,

Facts and Figures on Materials Science and Nanotechnology Progress and Investment. ACS Nano15(10):15940-15952, 2021. [Journal: Article] [CI: 42] [IF: 18]
DOI: 10.1021/acsnano.1c03992 SCOPUS: 85112525556.

Nunes R., Bogas S., Faria M.J., Gonçalves H., Lúcio M., Viseu T., Sarmento B., das Neves J.,

Electrospun fibers for vaginal administration of tenofovir disoproxil fumarate and emtricitabine in the context of topical pre-exposure prophylaxis. Journal of Controlled Release334:453-462, 2021. [Journal: Article] [CI: 10] [IF: 11,5]
DOI: 10.1016/j.jconrel.2021.05.003 SCOPUS: 85105809643.

Facchinatto W.M., Galante J., Mesquita L., Silva D.S., Martins dos Santos D., Moraes T.B., Campana-Filho S.P., Colnago L.A., Sarmento B., das Neves J.,

Clotrimazole-loaded N-(2-hydroxy)-propyl-3-trimethylammonium, O-palmitoyl chitosan nanoparticles for topical treatment of vulvovaginal candidiasis. Acta Biomaterialia125:312-321, 2021. [Journal: Article] [CI: 22] [IF: 10,6]
DOI: 10.1016/j.actbio.2021.02.029 SCOPUS: 85102282925.

Das Neves J., Sverdlov Arzi R., Sosnik A.,

Molecular and cellular cues governing nanomaterial-mucosae interactions: From nanomedicine to nanotoxicology. Chemical Society Reviews49(14):5058-5100, 2020. [Journal: Review] [CI: 33] [IF: 54,6]
DOI: 10.1039/c8cs00948a SCOPUS: 85088493930.

Melo M., Nunes R., Sarmento B., Das Neves J.,

Colorectal distribution and retention of polymeric nanoparticles following incorporation into a thermosensitive enema. Biomaterials Science7(9):3801-3811, 2019. [Journal: Article] [CI: 12] [IF: 6,2]
DOI: 10.1039/c9bm00759h SCOPUS: 85071385635.

Fernandes T., Baxi K., Sawarkar S., Sarmento B., das Neves J.,

Vaginal multipurpose prevention technologies: promising approaches for enhancing women’s sexual and reproductive health. Expert Opinion on Drug Delivery17(3):379-393, 2020. [Journal: Review] [CI: 7] [IF: 6,6]
DOI: 10.1080/17425247.2020.1728251 SCOPUS: 85079724834.

Gabriel L., Almeida H., Avelar M., Sarmento B., Das Neves J.,

MPTHub: An Open-Source Software for Characterizing the Transport of Particles in Biorelevant Media. Nanomaterials12(11):, 2022. [Journal: Article] [CI: 1] [IF: 5,3]
DOI: 10.3390/nano12111899 SCOPUS: 85131082232.