Joana Gomes is BSc in Biochemistry by the University of Porto (2005) and MSc in Molecular and Oncology Medicine by the Medical Faculty of the University of Porto. In 2012, she obtained an International joint PhD degree in Biomedicine (University of Porto, Portugal) and Microbiology (University Paris XI, France) with her PhD developed at Institut Pasteur (Paris), IPATIMUP (Porto) and Copenhagen University (Denmark). Since 2007, Joana Gomes has the accreditation of Direcção Geral de Veterinária as a competent person for animal experiments (FELASA Category C).
Joana Gomes is currently a researcher at the Glycobiology in Cancer group, at I3S/Ipatimup, University of Porto, focusing her research in understanding the role of glycosylation in gastrointestinal (GI) cancer therapy resistance, particularly glycoimmunology, towards the identification of novel biomarkers for patients' stratification and targeted cancer therapy development. She is deeply involved in the coordination of clinical samples and its data analysis as well as the experimental procedures using gastrointestinal mice models.
Joana Gomes is co-author of 42 peer-reviewed publications (H-index 22) and has participated in several research projects financed by national and international institutions.
Selected Publications
Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading?. Cancer Cell36(1):6-16, 2019. [Journal: Review] [CI: 333] [IF: 26,6]
DOI: 10.1016/j.ccell.2019.06.006 SCOPUS: 85067650826
Rodrigues J.G., Duarte H.O., Gomes C., Balmaña M., Martins Á.M., Hensbergen P.J., de Ru A.H., Lima J., Albergaria A., van Veelen P.A., Wuhrer M., Gomes J., Reis C.A.
Terminal α2,6-sialylation of epidermal growth factor receptor modulates antibody therapy response of colorectal cancer cells. Cellular Oncology44(4):835-850, 2021. [Journal: Article] [CI: 20] [IF: 7,1]
DOI: 10.1007/s13402-021-00606-z SCOPUS: 85104515471
Duarte H.O., Rodrigues J.G., Gomes C., Hensbergen P.J., Ederveen A.L.H., de Ru A.H., Mereiter S., Polónia A., Fernandes E., Ferreira J.A., van Veelen P.A., Santos L.L., Wuhrer M., Gomes J., Reis C.A.
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab. Oncogene40(21):3719-3733, 2021. [Journal: Article] [CI: 33] [IF: 8,8]
DOI: 10.1038/s41388-021-01801-w SCOPUS: 85105357480
Duarte H.O., Reis C.A., Gomes J.
Insights on ErbB glycosylation – contributions to precision oncology. Trends in Cancer8(6):448-455, 2022. [Journal: Review] [CI: 9] [IF: 18,4]
DOI: 10.1016/j.trecan.2022.02.003 SCOPUS: 85125707694
Duarte H.O., Balmaña M., Mereiter S., Osório H., Gomes J., Reis C.A.
Gastric cancer cell glycosylation as a modulator of the ErbB2 oncogenic receptor. International Journal of Molecular Sciences18(11):, 2017. [Journal: Article] [CI: 30] [IF: 3,7]
DOI: 10.3390/ijms18112262 SCOPUS: 85032689258
Rodrigues J.G., Duarte H.O., Reis C.A., Gomes J.
Aberrant protein glycosylation in cancer: Implications in targeted therapy. Biochemical Society Transactions49(2):843-854, 2021. [Journal: Review] [CI: 17] [IF: 4,9]
DOI: 10.1042/BST20200763 SCOPUS: 85105618493
Diniz F., Lamas S., Osório H., Aguiar P., Freitas D., Gärtner F., Sarmento B., Reis C.A., Gomes J.
Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer. Acta Biomaterialia170:142-154, 2023. [Journal: Article] [CI: 5] [IF: 9.4]
DOI: 10.1016/j.actbio.2023.08.014 SCOPUS: 85169921927
Diniz F., Azevedo M., Sousa F., Osório H., Campos D., Sampaio P., Gomes J., Sarmento B., Reis C.A.
Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions. Materials Today Bio16:, 2022. [Journal: Article] [CI: 4] [IF: 8,2]
DOI: 10.1016/j.mtbio.2022.100417 SCOPUS: 85137679101
Diniz F., Coelho P., Duarte H.O., Sarmento B., Reis C.A., Gomes J.
Glycans as Targets for Drug Delivery in Cancer. Cancers14(4):, 2022. [Journal: Review] [CI: 24] [IF: 5,2]
DOI: 10.3390/cancers14040911 SCOPUS: 85124361765
Ferreira J.A., Magalhães A., Gomes J., Peixoto A., Gaiteiro C., Fernandes E., Santos L.L., Reis C.A.
Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics. Cancer Letters387:32-45, 2017. [Journal: Review] [CI: 66] [IF: 6,5]
DOI: 10.1016/j.canlet.2016.01.044 SCOPUS: 84957693489
Gomes J., Mereiter S., Magalhães A., Reis C.A.
Early GalNAc O-Glycosylation: Pushing the Tumor Boundaries. Cancer Cell32(5):544-545, 2017. [Journal: Short Survey] [CI: 11] [IF: 22,8]
DOI: 10.1016/j.ccell.2017.10.010 SCOPUS: 85033695819