PT
creating a
healthier future
Ana Filipa Costa
Glycobiology in Cancer
Technician

Ana Filipa Costa is graduated in Biology and Master in Cellular and Molecular Biology by the Faculty of Sciences of the University of Porto. She concluded the master's degree in 2016, after presenting the dissertation: “Inhibition of cholinergic neurotransmission by ß3-adrenergic receptors in the urinary bladder of rats: role of the release of adenosine and activation of A1 receptors” carried out in the Laboratory of Pharmacology and Neurobiology of ICBAS- University of Porto (supervised by Dr. Paulo Correia de Sá), where she published 2 publications as a co-author. She was previously a Master Research Fellow at I3s - Instituto de Investigação e Inovação in the Glycobiology in Cancer group, (Project PI: GLYCOkiller (POCI-01-0145-FEDER-029780). She is currently a PhD student under the guidance of Dr. Catarina Gomes, being an author of a publication and co-author of 1 publication.

Selected Publications

Costa A.F., Senra E., Faria-Ramos I., Teixeira A., Morais J., Pacheco M., Reis C.A., Gomes C.
ST3GalIV drives SLeX biosynthesis in gastrointestinal cancer cells and associates with cancer cell motility. Glycoconjugate Journal40(4):421-433, 2023. [Journal: Article] [CI: 1] [IF: 2.7]
DOI: 10.1007/s10719-023-10113-y SCOPUS: 85153090571

Costa A.F., Campos D., Reis C.A., Gomes C.
Targeting Glycosylation: A New Road for Cancer Drug Discovery. Trends in Cancer6(9):757-766, 2020. [Journal: Review] [CI: 177] [IF: 14,2]
DOI: 10.1016/j.trecan.2020.04.002 SCOPUS: 85084227209

Gomes C., Almeida A., Barreira A., Calheiros J., Pinto F., Abrantes R., Costa A., Polonia A., Campos D., Osório H., Sousa H., Pinto-De-Sousa J., Kolarich D., Reis C.A.
Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas. Theranostics9(24):7431-7446, 2020. [Journal: Article] [CI: 41] [IF: 11,6]
DOI: 10.7150/thno.33858 SCOPUS: 85074719039

Silva I., Magalhães-Cardoso M.T., Ferreirinha F., Moreira S., Costa A.F., Silva D., Vieira C., Silva-Ramos M., Correia-de-Sá P.
β3 Adrenoceptor-induced cholinergic inhibition in human and rat urinary bladders involves the exchange protein directly activated by cyclic AMP 1 favoring adenosine release. British Journal of Pharmacology177(7):1589-1608, 2020. [Journal: Article] [CI: 12] [IF: 8,7]
DOI: 10.1111/bph.14921 SCOPUS: 85079127164

Silva I., Costa A.F., Moreira S., Ferreirinha F., Magalhães-Cardoso M.T., Calejo I., Silva-Ramos M., Correia-de-Sá P.
Inhibition of cholinergic neurotransmission by β3-adrenoceptors depends on adenosine release and A1-receptor activation in human and rat urinary bladders. American Journal of Physiology - Renal Physiology313(2):F388-F403, 2017. [Journal: Article] [CI: 36] [IF: 3,2]
DOI: 10.1152/ajprenal.00392.2016 SCOPUS: 85026803975