Where Ideas Grow
Inês Gonçalves
Group leader

Inês de Castro Gonçalves de Almada Lobo was born in 1981 in the city of Porto. Inês Gonçalves is married, mother of 3 children and research scientist at INEB – Instituto de Engenharia Biomédica / i3S.

Graduated in Microbiology from Escola Superior de Biotecnologia, Universidade Católica Portuguesa in 2003. She got her PhD in Biomedical Engineering from the Faculty of Engineering, University of Porto in 2009. Her thesis was based on biomaterials for blood contact, focusing on the development of molecularly engineered self-assembled monolayers and polymers to bind albumin and reduce thrombus formation in cardiovascular devices. The work was developed at INEB (Biomedical Engineering Institute), in Porto, under the supervision of Prof. Mário Barbosa and Dr. Cristina Martins and at UWEB (University of Washington Engineered Biomaterials), in Seattle, under the supervision of Prof. Buddy Ratner.

Between 2010 and 2013 was Post-Doc at INEB and IPATIMUP, focusing her work on biomaterials to prevent gastric cancer, developing glycosylated mucoadhesive microspheres to eliminate gastric infection caused by Helicobacter pylori. In 2013 was hired as researcher by INEB, continuing this line of work, and developing a new area of research using biocompatible and antimicrobial graphene-based biomaterials for different biomedical applications.

Inês Gonçalves is also Invited Assistant Professor at FEUP – Faculty of Engineering of Porto University (since 2010) and at ICBAS – Instituto de Ciências Biomédicas Abel Salazar (since 2013), teaching in the Integrated Master in BioEngineering (MIB) and in the Biomedical Engineering Master.

She has been involved in 9 research projects, 3 of them as principal investigator, co-organized 9 national/international conferences and is coordinator of the initiative “Porto de Crianças” at INEB that aims to provide primary school children a first contact with science.

Inês C. Gonçalves is the author of 23 papers in peer reviewed international journals and has one filled international patent. She has given over 40 oral communications and presented over 25 posters in international conferences. She has supervised/co-supervised 8 research assistants (2 ongoing), 11 MSc students (2 ongoing) and 4 PhD students (2 ongoing). Her work has been recognized with 6 national and international awards, including "Pulido Valente Science Prize 2006” and "Medal of Honor L'Oreal for women in science 2013".

December, 2017

Selected Publications

Pereira A.T., Henriques P.C., Schneider K.H., Pires A.L., Pereira A.M., Martins M.C.L., Magalhaes F.D., Bergmeister H., Goncalves I.C.,
Graphene-based materials: The key for the successful application of pHEMA as a blood-contacting device. Biomaterials Science9(9):3362-3377, 2021. [Journal: Article] [CI: 5] [IF: 7,6]
DOI: 10.1039/d0bm01699c SCOPUS: 85105463372.


Pereira A.T., Schneider K.H., Henriques P.C., Grasl C., Melo S.F., Fernandes I.P., Kiss H., Martins M.C.L., Bergmeister H., Gonçalves I.C.,
Graphene Oxide Coating Improves the Mechanical and Biological Properties of Decellularized Umbilical Cord Arteries. ACS Applied Materials and Interfaces13(28):32662-32672, 2021. [Journal: Article] [CI: 3] [IF: 10,4]
DOI: 10.1021/acsami.1c04028 SCOPUS: 85111180304.


Henriques P.C., Pereira A.T., Bogas D., Fernandes J.R., Pinto A.M., Magalhães F.D., Gonçalves I.C.,
Graphene films irradiated with safe low-power NIR-emitting diodes kill multidrug resistant bacteria. Carbon180:10-21, 2021. [Journal: Article] [CI: 3] [IF: 11,3]
DOI: 10.1016/j.carbon.2021.04.085 SCOPUS: 85105267175.


Borges I., Henriques P.C., Gomes R.N., Pinto A.M., Pestana M., Magalhães F.D., Gonçalves I.C.,
Exposure of smaller and oxidized graphene on polyurethane surface improves its antimicrobial performance. Nanomaterials10(2):, 2020. [Journal: Article] [CI: 11] [IF: 5,1]
DOI: 10.3390/nano10020349 SCOPUS: 85079714581.


Costa-Almeida R., Bogas D., Fernandes J.R., Timochenco L., Silva F.A.L.S., Meneses J., Gonçalves I.C., Magalhães F.D., Pinto A.M.,
Near-infrared radiation-based mild photohyperthermia therapy of non-melanoma skin cancer with PEGylated reduced nanographene oxide. Polymers12(8):, 2020. [Journal: Article] [CI: 14] [IF: 4,3]
DOI: 10.3390/POLYM12081840 SCOPUS: 85090400583.


Henriques P.C., Pereira A.T., Pires A.L., Pereira A.M., Magalhães F.D., Gonçalves I.C.,
Graphene Surfaces Interaction with Proteins, Bacteria, Mammalian Cells, and Blood Constituents: The Impact of Graphene Platelet Oxidation and Thickness. ACS Applied Materials and Interfaces12(18):21020-21035, 2020. [Journal: Article] [CI: 21] [IF: 9,2]
DOI: 10.1021/acsami.9b21841 SCOPUS: 85084379485.


Melo S.F., Neves S.C., Pereira A.T., Borges I., Granja P.L., Magalhães F.D., Gonçalves I.C.,
Incorporation of graphene oxide into poly(&ε;-caprolactone) 3D printed fibrous scaffolds improves their antimicrobial properties. Materials Science and Engineering C109:, 2020. [Journal: Article] [CI: 20] [IF: 7,3]
DOI: 10.1016/j.msec.2019.110537 SCOPUS: 85077755863.


Pereira A.T., Henriques P.C., Costa P.C., Martins M.C.L., Magalhães F.D., Gonçalves I.C.,
Graphene oxide-reinforced poly(2-hydroxyethyl methacrylate) hydrogels with extreme stiffness and high-strength. Composites Science and Technology184:, 2019. [Journal: Article] [CI: 14] [IF: 7,1]
DOI: 10.1016/j.compscitech.2019.107819 SCOPUS: 85072771699.


Gomes R.N., Borges I., Pereira A.T., Maia A.F., Pestana M., Magalhães F.D., Pinto A.M., Gonçalves I.C.,
Antimicrobial graphene nanoplatelets coatings for silicone catheters. Carbon139:635-647, 2018. [Journal: Article] [CI: 30] [IF: 7,5]
DOI: 10.1016/j.carbon.2018.06.044 SCOPUS: 85050155850.


Henriques P.C., Borges I., Pinto A.M., Magalhães F.D., Gonçalves I.C.,
Fabrication and antimicrobial performance of surfaces integrating graphene-based materials. Carbon132:709-732, 2018. [Journal: Review] [CI: 54] [IF: 7,5]
DOI: 10.1016/j.carbon.2018.02.027 SCOPUS: 85043307316.


Pinto A.M., Goncalves C., Sousa D.M., Ferreira A.R., Moreira J.A., Goncalves I.C., Magalhães F.D.,
Smaller particle size and higher oxidation improves biocompatibility of graphene-based materials. Carbon99:318-329, 2016. [Journal: Article] [CI: 50] [IF: 6,3]
DOI: 10.1016/j.carbon.2015.11.076 SCOPUS: 84959449298.


Henriques P.C., Costa L.M., Seabra C.L., Antunes B., Silva-Carvalho R., Junqueira-Neto S., Maia A.F., Oliveira P., Magalhães A., Reis C.A., Gartner F., Touati E., Gomes J., Costa P., Martins M.C., Gonçalves I.C.,
Orally administrated chitosan microspheres bind Helicobacter pylori and decrease gastric infection in mice. Acta Biomaterialia114:206-220, 2020. [Journal: Article] [CI: 10] [IF: 8,9]
DOI: 10.1016/j.actbio.2020.06.035 SCOPUS: 85088806369.


Parreira P., Monteiro C., Graça V., Gomes J., Maia S., Gomes P., Gonçalves I.C., Martins M.C.L.,
Surface Grafted MSI-78A Antimicrobial Peptide has High Potential for Gastric Infection Management. Scientific Reports9(1):, 2019. [Journal: Article] [CI: 9] [IF: 4]
DOI: 10.1038/s41598-019-53918-4 SCOPUS: 85075982293.


Seabra C.L., Nunes C., Brás M., Gomez-Lazaro M., Reis C.A., Gonçalves I.C., Reis S., Martins M.C.L.,
Lipid nanoparticles to counteract gastric infection without affecting gut microbiota. European Journal of Pharmaceutics and Biopharmaceutics127:378-386, 2018. [Journal: Article] [CI: 18] [IF: 4,7]
DOI: 10.1016/j.ejpb.2018.02.030 SCOPUS: 85044023662.


Seabra C.L., Nunes C., Gomez-Lazaro M., Correia M., Machado J.C., Gonçalves I.C., Reis C.A., Reis S., Martins M.C.L.,
Docosahexaenoic acid loaded lipid nanoparticles with bactericidal activity against Helicobacter pylori. International Journal of Pharmaceutics519(1-2):128-137, 2017. [Journal: Article] [CI: 30] [IF: 3,9]
DOI: 10.1016/j.ijpharm.2017.01.014 SCOPUS: 85010199517.


Gonçalves I.C., Magalhães A., Costa A.M.S., Oliveira J.R., Henriques P.C., Gomes P., Reis C.A., Martins M.C.L.,
Bacteria-targeted biomaterials: Glycan-coated microspheres to bind Helicobacter pylori. Acta Biomaterialia33:40-50, 2016. [Journal: Article] [CI: 12] [IF: 6,3]
DOI: 10.1016/j.actbio.2016.01.029 SCOPUS: 84959468144.


Gonçalves I.C., Henriques P.C., Seabra C.L., Martins M.C.L.,
The potential utility of chitosan micro/nanoparticles in the treatment of gastric infection. Expert Review of Anti-Infective Therapy12(8):981-992, 2014. [Journal: Review] [CI: 36] [IF: 3,5]
DOI: 10.1586/14787210.2014.930663 SCOPUS: 84904003586.


Gonçalves I.C., Martins M.C.L., Barbosa M.A., Ratner B.D.,
Protein adsorption on 18-alkyl chains immobilized on hydroxyl-terminated self-assembled monolayers. Biomaterials26(18):3891-3899, 2005. [Journal: Article] [CI: 45] [IF: 4,7]
DOI: 10.1016/j.biomaterials.2004.10.006 SCOPUS: 11144307278.


Rodrigues S.N., Gonçalves I.C., Martins M.C.L., Barbosa M.A., Ratner B.D.,
Fibrinogen adsorption, platelet adhesion and activation on mixed hydroxyl-/methyl-terminated self-assembled monolayers. Biomaterials27(31):5357-5367, 2006. [Journal: Article] [CI: 186] [IF: 5,2]
DOI: 10.1016/j.biomaterials.2006.06.010 SCOPUS: 33746216936.


Gonçalves I.C., Martins M.C.L., Barbosa M.A., Naeemi E., Ratner B.D.,
Selective protein adsorption modulates platelet adhesion and activation to oligo(ethylene glycol)-terminated self-assembled monolayers with C18 ligands. Journal of Biomedical Materials Research - Part A89(3):642-653, 2009. [Journal: Article] [CI: 21] [IF: 2,8]
DOI: 10.1002/jbm.a.32011 SCOPUS: 66249128976.


Gonçalves I.C., Martins M.C.L., Barbosa M.A., Ratner B.D.,
Protein adsorption and clotting time of pHEMA hydrogels modified with C18 ligands to adsorb albumin selectively and reversibly. Biomaterials30(29):5541-5551, 2009. [Journal: Article] [CI: 28] [IF: 7,4]
DOI: 10.1016/j.biomaterials.2009.06.025 SCOPUS: 68549112719.


Barbosa J.N., Martins M.C.L., Freitas S.C., Gonçalves I.C., Águas A.P., Barbosa M.A.,
Adhesion of human leukocytes on mixtures of hydroxyl- and methyl-terminated self-assembled monolayers: Effect of blood protein adsorption. Journal of Biomedical Materials Research - Part A93(1):12-19, 2010. [Journal: Article] [CI: 13] [IF: 3]
DOI: 10.1002/jbm.a.32480 SCOPUS: 77649225392.


Parreira P., Magalhaes A., Gonaçalves I.C., Gomes J., Vidal R., Reis C.A., Leckband D.E., Martins M.C.L.,
Effect of surface chemistry on bacterial adhesion, viability, and morphology. Journal of Biomedical Materials Research - Part A99 A(3):344-353, 2011. [Journal: Article] [CI: 40] [IF: 2,6]
DOI: 10.1002/jbm.a.33178 SCOPUS: 80055008019.


Gonçalves I.C., Martins M.C.L., Barbosa J.N., Oliveira P., Barbosa M.A., Ratner B.D.,
Platelet and leukocyte adhesion to albumin binding self-assembled monolayers. Journal of Materials Science: Materials in Medicine22(9):2053-2063, 2011. [Journal: Article] [CI: 18] [IF: 2,3]
DOI: 10.1007/s10856-011-4381-9 SCOPUS: 80755133542.


Fischer M., Baptista C.P., Gonçalves I.C., Ratner B.D., Sperling C., Werner C., Martins C.L., Barbosa M.A.,
The effect of octadecyl chain immobilization on the hemocompatibility of poly (2-hydroxyethyl methacrylate). Biomaterials33(31):7677-7685, 2012. [Journal: Article] [CI: 14] [IF: 7,6]
DOI: 10.1016/j.biomaterials.2012.07.007 SCOPUS: 84865188580.